在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protein lin-7 homolog C (LIN7C)

Recombinant Human Protein lin-7 homolog C (LIN7C)

  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-YP873657HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-EP873657HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-EP873657HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-BP873657HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-MP873657HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    LIN7C
  • Uniprot No.：
  • 別名：
    hLin 7; hLin7; LIN 7; Lin 7 homolog A; LIN 7A; LIN 7B; LIN 7C; Lin-7C; Lin7 homolog A; LIN7A; LIN7C; LIN7C_HUMAN; MALS 1; MALS; MALS-3; MALS1; Mammalian LIN 7 1; Mammalian lin seven protein 1; Mammalian lin-seven protein 3; Mammalian LIN7 1; MGC148143; Protein lin 7 homolog B; Protein lin 7 homolog C; Protein lin-7 homolog C; protein lin7 homolog A ; Tax interaction protein 33; TIP 33; TIP33; VELI 1; Veli 1 protein; Veli-3; VELI1; Velis; Vertebrate LIN 7 homolog 1; Vertebrate lin-7 homolog 3; Vertebrate LIN7 homolog 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-197
  • 氨基酸序列
    AALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV REVYEHVYET VDISSSPEVR ANATAKATVA AFAASEGHSH PRVVELPKTE EGLGFNIMGG KEQNSPIYIS RIIPGGIADR HGGLKRGDQL LSVNGVSVEG EHHEKAVELL KAAQGKVKLV VRYTPKVLEE MESRFEKMRS AKRRQQT
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules. This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
  • 基因功能參考文獻：
    1. Data show that mirtazapine caused substantial up-regulation of the Lin-7C/beta-catenin pathway in a metastatic squamous cell carcinomas (hSCCs) cell line and melanoma-derived cell line. PMID: 24961284
    2. The Dlg1-MPP7-Mals3 heterotrimer consists of 2 pairs of heterodimeric L27 domains. These 2 dimers are asymmetric due to the large difference between the N- and C-terminal tandem L27 domain of MPP7. PMID: 20702775
    3. analysis of the solution structure of the heterodimer composed of the L27 domains from LIN-2 and LIN-7 PMID: 16147993
    4. LIN7C is a PDZ protein that interacts with human papillomavirus-16 E6 and forms a tripartite complex with MPP7 and DLG1, regulating the stability and localization of DLG1 to cell junctions. PMID: 17237226
    5. Overexpression of the Lin-7C gene in an OSCC cell clone does not contribute to underproliferation but results in a noninvasive phenotype with elevated beta-catenin expression. PMID: 17942893
    6. Allelic and haplotype association was found between both BDNF and adult ADHD, and LIN-7 and adult ADHD. PMID: 18286632

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Cell junction, synapse, postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction.
  • 蛋白家族：
    Lin-7 family
  • 數據庫鏈接：

    HGNC: 17789

    OMIM: 612332

    KEGG: hsa:55327

    STRING: 9606.ENSP00000278193

    UniGene: Hs.91393



主站蜘蛛池模板： 日韩亚洲欧美中文在线| 国产精品亚洲综合色区| 国产v在线最新观看视频| 国产精品无码久久久久久| 国产麻豆精品一区| 99re热视频这里只精品| 国产亚洲精品ae86| 国产亚洲精品久久久久久无| 午夜亚洲影院在线观看| 伊人久久精品无码av一区| 无码人妻aⅴ一区二区三区69岛 | 丝袜老师办公室里做好紧好爽| 蜜臀精品国产高清在线观看| 18禁止午夜福利体验区| 久久精品99国产精品日本| 精品国产一区二区三区四区vr| 亚洲精品一区二区三区新线路| 欧美精品欧美人与动人物牲交| 国产成久久免费精品av片| 国产成人精品手机在线观看| 日日鲁鲁鲁夜夜爽爽狠狠视频97 | 狠狠躁18三区二区一区| 亚洲精品一区二区久| 国产乱人伦偷精品视频免观看| 本道久久综合无码中文字幕| 极品少妇高潮到爽| 亚洲五月综合缴情在线| 国产福利高颜值在线观看 | 亚洲欧美自拍制服另类图区| 三级特黄60分钟在线观看| 强迫大乳人妻中文字幕| 精品国产一区二区三区av 性色 | 久久亚洲国产精品123区| 亚洲第一a在线观看网站| 少妇粗大进出白浆嘿嘿视频| 天天干天天射天天操| 青青草国产精品一区二区| 成 人影片 免费观看在线| 欧美另类精品xxxx| 欧美国产激情18| 狠狠cao2020高清视频|