在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protein lin-7 homolog C (LIN7C)

Recombinant Human Protein lin-7 homolog C (LIN7C)

  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-YP873657HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-EP873657HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-EP873657HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-BP873657HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人LIN7C重組蛋白
  • 貨號：
    CSB-MP873657HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    LIN7C
  • Uniprot No.：
  • 別名：
    hLin 7; hLin7; LIN 7; Lin 7 homolog A; LIN 7A; LIN 7B; LIN 7C; Lin-7C; Lin7 homolog A; LIN7A; LIN7C; LIN7C_HUMAN; MALS 1; MALS; MALS-3; MALS1; Mammalian LIN 7 1; Mammalian lin seven protein 1; Mammalian lin-seven protein 3; Mammalian LIN7 1; MGC148143; Protein lin 7 homolog B; Protein lin 7 homolog C; Protein lin-7 homolog C; protein lin7 homolog A ; Tax interaction protein 33; TIP 33; TIP33; VELI 1; Veli 1 protein; Veli-3; VELI1; Velis; Vertebrate LIN 7 homolog 1; Vertebrate lin-7 homolog 3; Vertebrate LIN7 homolog 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-197
  • 氨基酸序列
    AALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV REVYEHVYET VDISSSPEVR ANATAKATVA AFAASEGHSH PRVVELPKTE EGLGFNIMGG KEQNSPIYIS RIIPGGIADR HGGLKRGDQL LSVNGVSVEG EHHEKAVELL KAAQGKVKLV VRYTPKVLEE MESRFEKMRS AKRRQQT
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules. This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
  • 基因功能參考文獻：
    1. Data show that mirtazapine caused substantial up-regulation of the Lin-7C/beta-catenin pathway in a metastatic squamous cell carcinomas (hSCCs) cell line and melanoma-derived cell line. PMID: 24961284
    2. The Dlg1-MPP7-Mals3 heterotrimer consists of 2 pairs of heterodimeric L27 domains. These 2 dimers are asymmetric due to the large difference between the N- and C-terminal tandem L27 domain of MPP7. PMID: 20702775
    3. analysis of the solution structure of the heterodimer composed of the L27 domains from LIN-2 and LIN-7 PMID: 16147993
    4. LIN7C is a PDZ protein that interacts with human papillomavirus-16 E6 and forms a tripartite complex with MPP7 and DLG1, regulating the stability and localization of DLG1 to cell junctions. PMID: 17237226
    5. Overexpression of the Lin-7C gene in an OSCC cell clone does not contribute to underproliferation but results in a noninvasive phenotype with elevated beta-catenin expression. PMID: 17942893
    6. Allelic and haplotype association was found between both BDNF and adult ADHD, and LIN-7 and adult ADHD. PMID: 18286632

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Cell junction, synapse, postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction.
  • 蛋白家族：
    Lin-7 family
  • 數據庫鏈接：

    HGNC: 17789

    OMIM: 612332

    KEGG: hsa:55327

    STRING: 9606.ENSP00000278193

    UniGene: Hs.91393



主站蜘蛛池模板： 日韩a无v码在线播放| a毛片免费全部播放自慰| 宅男午夜成年影视在线观看| 青青草国产精品人人爱| 欧美亚洲日韩不卡在线在线观看| 免费观看又色又爽又湿的视频 | 一区二区视频传媒有限公司| 国产亚洲va在线电影| 伊人婷婷六月狠狠狠去| 美女内射毛片在线看3d| 香港三级精品三级在线专区| 97在线视频人妻无码| 狠狠色噜噜狠狠狠777米奇小说| 大香线蕉伊人超碰| 免费看国产成年无码av| 国产精品久久久久高潮| 少妇无码av无码专区在线观看| 国产精品亚洲一区二区在线观看| 无码专区—va亚洲v天堂麻豆| 4480yy私人精品国产| 我的性奴的肉玩具1一17心奴 | 欧美va久久久噜噜噜久久| 性色av无码不卡中文字幕| 人妻丰满熟妇av无码区不卡 | 女被啪到深处喷水gif动态图| 欧美 日韩版国产在线播放| 未满小14洗澡无码视频网站| 免费看国产曰批40分钟| 国产伦人人人人人人性| 人人超碰人人超级碰国| 国产涩涩视频在线观看| 曰韩免费无码av一区二区| 99re6热精品视频在线观看| 欧美激性欧美激情在线| 色久悠悠婷婷综合在线亚洲 | 国产一区二区三区免费观看在线| 五月婷婷俺也去开心| 正在播放重口老熟女露脸| 国产精品国产三级国产剧情| 国产精品久久久久久久久鸭| 亚洲精品国产精品国自产|