在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protein dpy-30 homolog (DPY30)

Recombinant Human Protein dpy-30 homolog (DPY30)

  • 中文名稱：
    人DPY30重組蛋白
  • 貨號：
    CSB-YP861193HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人DPY30重組蛋白
  • 貨號：
    CSB-EP861193HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人DPY30重組蛋白
  • 貨號：
    CSB-EP861193HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DPY30重組蛋白
  • 貨號：
    CSB-BP861193HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DPY30重組蛋白
  • 貨號：
    CSB-MP861193HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DPY30
  • Uniprot No.：
  • 別名：
    Dpy-30-like protein; Dpy-30L; DPY30; DPY30_HUMAN; HDPY-30; Protein dpy-30 homolog; Saf19
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-99
  • 氨基酸序列
    MEPEQMLEGQ TQVAENPHSE YGLTDNVERI VENEKINAEK SSKQKVDLQS LPTRAYLDQT VVPILLQGLA VLAKERPPNP IEFLASYLLK NKAQFEDRN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
  • 基因功能參考文獻：
    1. Dpy30 role in cellular reprogramming and its interactions with Set1 complex PMID: 26691508
    2. results indicate that DPY30 has critical roles in the proliferation, migration, and invasion of gastric cancer cells, and suggest DPY30 might be a therapeutic target in gastric cancer PMID: 26147337
    3. Based on our structural data and cross-linking results, we suggest that Dpy30 may regulate H3K4 methylation according to its copy number in COMPASS PMID: 25542209
    4. these results form the basis for understanding how WRAD(DRY-30) differentially regulates SET1 family complexes in vivo. PMID: 25561738
    5. The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells. PMID: 25139354
    6. A deletion mutation and reduced DPY30 expression in a Spastic Paraplegia type 4 Japanese family. PMID: 24690193
    7. DPY30 regulates pathways in cellular senescence through ID protein expression. PMID: 23872946
    8. determination of the minimum motif of Ash2L that is required for DPY30 interaction; a structural model for the Ash2L-DPY30 interaction PMID: 22231628
    9. First report of SPG4 associated with partial deletions of both the SPAST and DPY30 genes. The partial heterozygous deletion of DPY30 could modify the phenotypic expression of SPG4 patients with this pedigree. PMID: 20857310
    10. The DPY-30 C-terminal domain structure, harboring the conserved DPY-30 motif, is composed of two alpha-helices linked by a sharp loop and forms a typical X-type four-helix bundle required for dimer formation. PMID: 19481096
    11. hDPY-30 (dpy-30-like protein) binds ASH2L directly. The evolutionarily conserved hDPY-30, ASH2L, RBBP5 and WDR5 likely constitute a subcomplex that is shared by all human Set1-like HMT complexes. PMID: 17500065

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Golgi apparatus, trans-Golgi network.
  • 蛋白家族：
    Dpy-30 family
  • 數據庫鏈接：

    HGNC: 24590

    OMIM: 612032

    KEGG: hsa:84661

    STRING: 9606.ENSP00000295066

    UniGene: Hs.531788



主站蜘蛛池模板： 午夜日本大胆裸艺术| 国产精品爽爽ⅴa在线观看| h漫全彩纯肉无码网站| 久久久久人妻一区二区三区| 髙清国产性猛交xxxand| 黑人猛挺进小莹的体内视频| 99久久精品国产一区二区| 久久久久国产精品熟女影院| 久久精品中文字幕| 午夜福利理论片高清在线| 国产成+人+综合+亚洲欧美| 国产狂喷潮在线观看| 免费大黄网站在线观| 伊人精品一本久久综合| 99国产揄拍国产精品人妻| 国产免费拔擦拔擦8x高清在线人| 国产精品99久久久久久www| 日本看片一二三区高清| 国产成人精选在线观看不卡| 中文字幕人妻无码视频| 久久久久爽爽爽爽一区老女人| 国产在线第一区二区三区| 亚洲成a人无码| 99久久无码一区人妻| 亚洲mv国产mv在线mv综合试看| 亚洲va欧美va国产va综合| 天美传媒一区二区| 成人国产三级在线观看| 风韵丰满熟妇啪啪区老老熟妇| 国产白浆喷水在线视频| 欧美日韩一本的免费高清视频| 色天使久久综合网天天| 国产无套内射又大又猛又粗又爽| 97国产超碰一区二区三区| 强行无套内谢大学生初次| 国语国产精精品国产国语清晰对话 | 日韩精品无码成人专区| 国产薄丝脚交视频在线观看| 亚洲自偷自偷偷色无码中文| 欧美乱人伦人妻中文字幕| 国产亚洲精品久久久久久小说|