在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein canopy homolog 2 (CNPY2)

  • 中文名稱:
    Recombinant Human Protein canopy homolog 2(CNPY2)
  • 貨號:
    CSB-YP896486HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Protein canopy homolog 2(CNPY2)
  • 貨號:
    CSB-EP896486HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Protein canopy homolog 2(CNPY2)
  • 貨號:
    CSB-EP896486HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Protein canopy homolog 2(CNPY2)
  • 貨號:
    CSB-BP896486HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Protein canopy homolog 2(CNPY2)
  • 貨號:
    CSB-MP896486HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Canopy 2 homolog (zebrafish); Cnpy2; CNPY2_HUMAN; MIR-interacting saposin-like protein; MSAP; Protein canopy homolog 2; Putative secreted protein ZSIG9; TMEM4; Transmembrane protein 4; UNQ1943/PRO4426; ZSIG9
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    21-182
  • 氨基酸序列
    RRSQDLHCGA CRALVDELEW EIAQVDPKKT IQMGSFRINP DGSQSVVEVP YARSEAHLTE LLEEICDRMK EYGEQIDPST HRKNYVRVVG RNGESSELDL QGIRIDSDIS GTLKFACESI VEEYEDELIE FFSREADNVK DKLCSKRTDL CDHALHISHD EL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.
  • 基因功能參考文獻:
    1. CNPY2 knockout resulted in the significant suppression of MHCC97H cell proliferation, tumor growth, and hemorrhage. PMID: 30415246
    2. Overexpression of CNPY2 can activate the AKT/GSK3beta pathway, which leads to the inactivation of GSK-3beta. The inactivation of GSK-3beta increases the level of Snail, and then decreases the expression of E-cadherin to promote EMT. PMID: 29569784
    3. CNPY2 can serve as a therapeutic target to promote the effect of chemotherapy in non-small cell lung cancer. PMID: 29864955
    4. CNPY2 isoform2 represents as a novel and valuable prognostic indicator for colorectal cancer patients. PMID: 29135454
    5. These findings suggested that CNPY2 promoted cancer cell growth in renal cell carcinoma cells through regulating TP53 gene expression. PMID: 28235487
    6. CNPY2 may play a critical role in colorectal cancer development by enhancing cell proliferation, migration, and angiogenesis and by inhibiting apoptosis through negative regulation of the p53 pathway PMID: 26835537
    7. CNPY2 is a HIF-1alpha-regulated, secreted angiogenic growth factor that promotes smooth muscle cell migration, proliferation, and tissue revascularization. PMID: 25589425
    8. Our results are consistent with an important role of FGF21 and Cnpy2/Msap in the regulation of LDLRs in cultured cells. PMID: 22378787
    9. MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain in fetal and adult brain. PMID: 12826659

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum.
  • 蛋白家族:
    Canopy family
  • 組織特異性:
    Expressed in different tissues. Highest levels are detected in adult placenta, liver and pancreas.
  • 數據庫鏈接:

    HGNC: 13529

    OMIM: 605861

    KEGG: hsa:10330

    STRING: 9606.ENSP00000273308

    UniGene: Hs.8752



主站蜘蛛池模板: 国产精品人成视频免费999| 久久一本人碰碰人碰| 国产精品久久久久久久久久妞妞 | 狠狠色噜噜狠狠狠狠色综合网| 亚洲精品一卡2卡三卡4卡| 久久久久99精品成人片| 人妻无码一区二区三区四区| 特大巨黑吊xxxx高潮| 国产一区二区女内射| 人妻aⅴ中文字幕| 黑人猛挺进小莹的体内视频| 四虎国产精品亚洲一区久久特色| 久久久久青草线综合超碰| 国产在线观看免费视频软件 | 色老99久久精品偷偷鲁| 无码日韩精品一区二区三区免费| 国产精品毛多多水多| 精品无码三级在线观看视频| 少妇高清精品毛片在线视频| 免费看女人与善牲交| 97国产在线看片免费人成视频| 亚洲色成人一区二区三区| 天堂中文在线www天堂在线| 国产精品久久久久久久久久久久午夜片| 老熟妇仑乱一区二区视頻| 日本无遮挡真人祼交视频 | 国精品午夜福利视频导航| 欧美综合区自拍亚洲综合绿色| 日韩精品久久久久久免费| 成 人片 黄 色 大 片| 亚洲欧美国产毛片在线| 1000部又爽又黄无遮挡的视频 | 精品国产乱码久久久人妻| 国产成人综合色视频精品| 免费人成在线视频无码| 无码精品一区二区三区免费视频| 大胆欧美熟妇xx| 久久伊人五月丁香狠狠色| 51社区精品视频| 2021麻豆剧传媒一二三区| 亚洲熟妇丰满多毛xxxx|