在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein-arginine deiminase type-3 (PADI3)

In Stock
  • 中文名稱:
    人PADI3重組蛋白
  • 貨號:
    CSB-YP891552HU
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    PADI3
  • Uniprot No.:
  • 別名:
    PADI3; PADI3_HUMAN; PDI3; Peptidyl arginine deiminase; type III; Peptidylarginine deiminase III; Protein arginine deiminase type 3; Protein arginine deiminase type III; Protein-arginine deiminase type III; Protein-arginine deiminase type-3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    Yeast
  • 分子量:
    76.7kDa
  • 表達區域:
    1-664aa
  • 氨基酸序列
    MSLQRIVRVSLEHPTSAVCVAGVETLVDIYGSVPEGTEMFEVYGTPGVDIYISPNMERGRERADTRRWRFDATLEIIVVMNSPSNDLNDSHVQISYHSSHEPLPLAYAVLYLTCVDISLDCDLNCEGRQDRNFVDKRQWVWGPSGYGGILLVNCDRDDPSCDVQDNCDQHVHCLQDLEDMSVMVLRTQGPAALFDDHKLVLHTSSYDAKRAQVFHICGPEDVCEAYRHVLGQDKVSYEVPRLHGDEERFFVEGLSFPDAGFTGLISFHVTLLDDSNEDFSASPIFTDTVVFRVAPWIMTPSTLPPLEVYVCRVRNNTCFVDAVAELARKAGCKLTICPQAENRNDRWIQDEMELGYVQAPHKTLPVVFDSPRNGELQDFPYKRILGPDFGYVTREPRDRSVSGLDSFGNLEVSPPVVANGKEYPLGRILIGGNLPGSSGRRVTQVVRDFLHAQKVQPPVELFVDWLAVGHVDEFLSFVPAPDGKGFRMLLASPGACFKLFQEKQKCGHGRALLFQGVVDDEQVKTISINQVLSNKDLINYNKFVQSCIDWNREVLKRELGLAECDIIDIPQLFKTERKKATAFFPDLVNMLVLGKHLGIPKPFGPIINGCCCLEEKVRSLLEPLGLHCTFIDDFTPYHMLHGEVHCGTNVCRKPFSFKWWNMVP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the deimination of arginine residues of proteins.
  • 基因功能參考文獻:
    1. The two enzymes PADI3 and TGM3, responsible for posttranslational protein modifications, and their target structural protein TCHH are all involved in hair shaft formation. PMID: 27866708
    2. Crystals of PAD3 obtained using polyethylene glycol 400 as a precipitant diffracted to 2.95 A resolution using synchrotron radiation PMID: 22684066
    3. PAD3 is co-located with filaggrin within the filamentous matrix of the deeper corneocytes where the protein is deiminated. PMID: 16091842
    4. PADI3 expression is driven by Sp1/Sp3 and NF-Y binding to the promoter region PMID: 16671893
    5. cytoplasmic S100A3 within the cuticular layer is mostly co-localized with the type III isoform of peptidylarginine deiminase (PAD3) PMID: 18083705
    6. Peptidylarginine deiminase Intergenic Enhancer is a strong enhancer of the PADI3 promoter in Ca2+-differentiated epidermal keratinocytes, and requires bound PMID: 18923650
    7. These results reveal the molecular bases of the expression specificity of PADI1 and PADI3 during keratinocyte differentiation through a long-range enhancer and support a model of PADI gene regulation depending on c-Jun-JunD competition. PMID: 18952102

    顯示更多

    收起更多

  • 相關疾病:
    Uncombable hair syndrome 1 (UHS1)
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Protein arginine deiminase family
  • 組織特異性:
    Hair follicles, and epidermis at very low levels.
  • 數據庫鏈接:

    HGNC: 18337

    OMIM: 191480

    KEGG: hsa:51702

    STRING: 9606.ENSP00000364609

    UniGene: Hs.149195



主站蜘蛛池模板: 黑人又粗又大又硬a片| 国产高清视频在线观看97| 在线综合亚洲欧洲综合网站| 18禁黄久久久aaa片| 秋秋影视午夜福利高清 | 亚洲国产成人久久精品99| 欧美婷婷六月丁香综合| 欧美黑人巨大videos在线| 久久婷婷久久一区二区三区| 国产午夜福利片| 日本欧美视频在线观看| 国产亚洲精品久久77777| 无码高潮喷吹在线观看| 无码人妻aⅴ一区二区三区玉蒲团 日本三级香港三级人妇三 | 欧美精品成人v高清视频| 午夜福利国产成人无码gif动图| 艳妇乳肉豪妇荡乳| 18禁成人黄网站免费观看久久| 婷婷色中文字幕综合在线| 无码av高潮抽搐流白浆| 欧美疯狂做受xxxx高潮| 无码人妻丰满熟妇奶水区码| 日本少妇自慰免费完整版| 中文字幕乱码免费专区| 国产午夜亚洲精品久久| 欧美z0zo人禽交欧美人禽交| 精品久久久无码中文字幕| 成人亚洲欧美激情在线电影| 国产亚洲精品电影网站在线观看 | 日产无码中文字幕av| 在线成人www免费观看视频| 一本色道久久88精品综合| 国产原创av中文在线观看| 另类亚洲综合区图片区小说| 人与禽性视频77777| 精品无码国产自产拍在线观看蜜| 女被男啪到哭的视频网站| 久久99亚洲精品久久频| 亚洲日韩精品国产一区二区三区| 综合色区国产亚洲另类| 国产精品老熟女露脸视频|