在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protein arginine N-methyltransferase 3 (PRMT3)

Recombinant Human Protein arginine N-methyltransferase 3 (PRMT3)

  • 中文名稱：
    人PRMT3重組蛋白
  • 貨號：
    CSB-YP018733HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PRMT3重組蛋白
  • 貨號：
    CSB-EP018733HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PRMT3重組蛋白
  • 貨號：
    CSB-EP018733HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PRMT3重組蛋白
  • 貨號：
    CSB-BP018733HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PRMT3重組蛋白
  • 貨號：
    CSB-MP018733HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    2010005E20Rik; 2410018A17Rik; AL033309; ANM3_HUMAN; Heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 3; Heterogeneous nuclear ribonucleoprotein methyltransferase like 3; Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 3; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; HMT1 hnRNP methyltransferase like 3; HMT1 hnRNP methyltransferase like 3 S. cerevisiae; HMT1-like 3; hnRNP methyltransferase like 3; HRMT1L3; PRMT 3; PRMT3; Protein arginine methyltransferase 3; Protein arginine N methyltransferase 3; Protein arginine N-methyltransferase 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-531
  • 氨基酸序列
    CSLASGATG GRGAVENEED LPELSDSGDE AAWEDEDDAD LPHGKQQTPC LFCNRLFTSA EETFSHCKSE HQFNIDSMVH KHGLEFYGYI KLINFIRLKN PTVEYMNSIY NPVPWEKEEY LKPVLEDDLL LQFDVEDLYE PVSVPFSYPN GLSENTSVVE KLKHMEARAL SAEAALARAR EDLQKMKQFA QDFVMHTDVR TCSSSTSVIA DLQEDEDGVY FSSYGHYGIH EEMLKDKIRT ESYRDFIYQN PHIFKDKVVL DVGCGTGILS MFAAKAGAKK VLGVDQSEIL YQAMDIIRLN KLEDTITLIK GKIEEVHLPV EKVDVIISEW MGYFLLFESM LDSVLYAKNK YLAKGGSVYP DICTISLVAV SDVNKHADRI AFWDDVYGFK MSCMKKAVIP EAVVEVLDPK TLISEPCGIK HIDCHTTSIS DLEFSSDFTL KITRTSMCTA IAGYFDIYFE KNCHNRVVFS TGPQSTKTHW KQTVFLLEKP FSVKAGEALK GKVTVHKSKK DPRSLTVTLT LNNSTQTYGL Q
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases. May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity.
  • 基因功能參考文獻：
    1. Findings uncover the existence of an extra-ribosomal complex consisting of PDCD2L, RPS2, and PRMT3 and support a role for PDCD2L in the late maturation of 40S ribosomal subunits. PMID: 27697862
    2. This work profilies substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues. PMID: 24320160
    3. Mutational defects in PRMT3 is not the cause of frontotemporal lobar degeneration. PMID: 23635657
    4. results show that protein arginine methyl transferase (PRMT)-3 and -5 methylate NaV1.5 in vitro, interact with NaV1.5 in human embryonic kidney (HEK) cells, and increase NaV1.5 current density PMID: 23912080
    5. The crystal structure of PRMT3 in complex with an inhibitor as well as kinetic analysis reveals an allosteric site of inhibition. PMID: 22795084
    6. release of VHL30 from the E3 ligase complex, promotes the binding of VHL30 to a protein arginine methyltransferase, PRMT3 PMID: 21942715
    7. The Tyr87Cys and Tyr87Glu-PRMT3 variants had markedly decreased affinity to ribosomal protein S2 and, consequently, reduced enzymatic activity compared to the wild-type enzyme. PMID: 21059412
    8. PRMT3 is a ribosomal protein methyltransferase that affects the cellular level of ribosomal subunits. PMID: 15175657
    9. DAL-1/4.1B protein significantly inhibits PRMT3 methylation of cellular substrates, which may affect mechanism through which DAL-1/4.1B affects tumor cell growth. PMID: 15334060
    10. Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively PMID: 19158082
    11. results suggest that the pathological mutation in the PABPN1 gene alters the protein conformation and induces a preferential interaction with type I PRMTs and Hsp70 chaperones PMID: 19641605

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
  • 數據庫鏈接：

    HGNC: 30163

    OMIM: 603190

    KEGG: hsa:10196

    STRING: 9606.ENSP00000331879

    UniGene: Hs.152337



主站蜘蛛池模板： 久久精品人人做人人爽老司机| 美女裸体无遮挡免费视频网站| 久久久久无码精品亚洲日韩| 亚洲精品午夜无码专区| av无码天堂一区二区三区| 亚洲爆乳aaa无码专区| 国内精品久久久久影院日本| 日本va欧美va精品发布| 亚洲精品久久区二区三区蜜桃臀| 久久久久青草线综合超碰| 国产白丝精品爽爽久久久久久蜜臀| 婷婷色五月开心五月| 少妇高潮喷水久久久久久久久久| 欧美色综合天天久久综合精品| 熟妇熟女乱妇乱女网站| 国内精品伊人久久久久影院对白| 一区二区三区毛aaaa片特级| 国产无遮挡又黄又爽高潮 | 日本一道高清一区二区三区| 免费国精产品wnw2544| 人妻内射一区二区在线视频| 久久精品第一国产久精国产宅男66| 国产精品无码永久免费888| 日韩av无码精品一二三区| 久久99精品国产麻豆| 久久久青草青草免费看| 日本高清二区视频久二区| 熟女肥臀白浆大屁股一区二区 | 国产精品午夜福利麻豆| 色综合无码av网站| 毛片无码国产| 香蕉午夜福利院| 国产成人无码精品一区二区三区| 无码专区—va亚洲v专区| 又爽又黄又无遮挡的视频| 色噜噜狠狼综合在线| 4480yy私人精品国产| 破了亲妺妺的处免费视频国产 | 精品成人免费一区二区不卡| 亚洲成aⅴ人最新无码| 欧美一区二区三区红桃小说|