在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein NEDD1 (NEDD1)

  • 中文名稱:
    人NEDD1重組蛋白
  • 貨號:
    CSB-YP822820HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NEDD1重組蛋白
  • 貨號:
    CSB-EP822820HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NEDD1重組蛋白
  • 貨號:
    CSB-EP822820HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NEDD1重組蛋白
  • 貨號:
    CSB-BP822820HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NEDD1重組蛋白
  • 貨號:
    CSB-MP822820HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    NEDD1
  • Uniprot No.:
  • 別名:
    FLJ35902; GCP WD; NEDD-1; NEDD1; NEDD1_HUMAN; Neural precursor cell expressed developmentally down-regulated protein 1; Neural precursor cell expressed, developmentally down regulated gene 1; Protein NEDD1; TUBGCP7
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-660
  • 氨基酸序列
    MQENLRFASS GDDIKIWDAS SMTLVDKFNP HTSPHGISSI CWSSNNNFLV TASSSGDKIV VSSCKCKPVP LLELAEGQKQ TCVNLNSTSM YLVSGGLNNT VNIWDLKSKR VHRSLKDHKD QVTCVTYNWN DCYIASGSLS GEIILHSVTT NLSSTPFGHG SNQSVRHLKY SLFKKSLLGS VSDNGIVTLW DVNSQSPYHN FDSVHKAPAS GICFSPVNEL LFVTIGLDKR IILYDTSSKK LVKTLVADTP LTAVDFMPDG ATLAIGSSRG KIYQYDLRML KSPVKTISAH KTSVQCIAFQ YSTVLTKSSL NKGCSNKPTT VNKRSVNVNA ASGGVQNSGI VREAPATSIA TVLPQPMTSA MGKGTVAVQE KAGLPRSINT DTLSKETDSG KNQDFSSFDD TGKSSLGDMF SPIRDDAVVN KGSDESIGKG DGFDFLPQLN SVFPPRKNPV TSSTSVLHSS PLNVFMGSPG KEENENRDLT AESKKIYMGK QESKDSFKQL AKLVTSGAES GNLNTSPSSN QTRNSEKFEK PENEIEAQLI CEPPINGSST PNPKIASSVT AGVASSLSEK IADSIGNNRQ NAPLTSIQIR FIQNMIQETL DDFREACHRD IVNLQVEMIK QFHMQLNEMH SLLERYSVNE GLVAEIERLR EENKRLRAHF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for mitosis progression. Promotes the nucleation of microtubules from the spindle.
  • 基因功能參考文獻:
    1. One important function of Aurora A in mitotic cells is to promote microtubule nucleation around the chromatin by phosphorylating NEDD1, and thereby to promote functional spindle assembly. PMID: 23273898
    2. The mice treated with small interfering (si) RNA targeting NEDD1 by the atelocollagen-mediated delivery system showed a significantly prolonged survival in a xenograft model of human gastric cancer. PMID: 23106787
    3. Data suggest that the NEDD1/gamma-tubulin interaction is finely tuned by multiple phosphorylation events in the S557-S574 region and is critical for spindle assembly. PMID: 22595525
    4. a direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome PMID: 20224777
    5. GCP-WD (NEDD1) broadly mediates targeting of the gamma-tubulin ring complex to sites of microtubule nucleation and to the mitotic spindle, which is essential for spindle formation. PMID: 16378099
    6. The NEED1 protein was characterized and its function in centriole duplication and spindle assembly determined. PMID: 16461362
    7. Data propose NEDD1 may be a promising target for controlling cell proliferation, in particular if targeted in combination with Plk1 inhibitors. PMID: 19243593
    8. Data suggest that sequential phosphorylation of Nedd1 by Cdk1 and Plk1 plays a role in targeting gamma tubulin ring complex to the centrosome by promoting the interaction of Nedd1 with the gammaTuRC component gamma-tubulin, during mitosis. PMID: 19509060

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 數據庫鏈接:

    HGNC: 7723

    OMIM: 600372

    KEGG: hsa:121441

    STRING: 9606.ENSP00000451211

    UniGene: Hs.270084



主站蜘蛛池模板: 国产av寂寞骚妇| 激情航班h版在线观看| 亚洲成av人片在线观看无码| 影音先锋女人aa鲁色资源| 精品精品国产男人的天堂| 2021国产精品香蕉在线观看| 亚洲成av人最新无码| 亚洲熟妇无码av在线播放| 亚洲精品一区国产欧美| 激情综合婷婷丁香五月情| 国精产品一区一区三区有限公司| 久久久久久九九99精品| 亚洲午夜成人久久久久久| 成人夜色视频网站在线观看| 中国少妇内射xxxhd免费| 精品福利一区二区三区免费视频| 成人午夜看黄在线尤物成人| 国产av偷闻女邻居内裤被发现| 图片区 小说区 区 亚洲五月| 国产精品久久久久9999小说| 亚洲国产成人精品福利| 久久精品中文字幕有码| 精品少妇无码av无码专区| 少妇暴力深喉囗交3p| 一本无码中文字幕在线观| 老色鬼永久精品网站| 国产精品久久久一区二区| 天天综合色天天综合色h| 蜜臀avwww国产天堂| 亚洲色大成网站www| 潮喷大喷水系列无码视频| 国内精品久久久久久久电影视| 99久久久无码国产精品不卡| 国产精品刮毛| 大狠狠大臿蕉香蕉大视频| 免费无遮挡无码永久视频| 日韩精品一区二区三区中文| 国内芒果精品自线一区2021| 国产3p露脸普通话对白| 欧美人与物videos另类xxxxx| 亚洲中文字幕伊人久久无码 |