在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein FAM83D (FAM83D)

  • 中文名稱:
    人FAM83D重組蛋白
  • 貨號:
    CSB-YP887979HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人FAM83D重組蛋白
  • 貨號:
    CSB-EP887979HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人FAM83D重組蛋白
  • 貨號:
    CSB-EP887979HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人FAM83D重組蛋白
  • 貨號:
    CSB-BP887979HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人FAM83D重組蛋白
  • 貨號:
    CSB-MP887979HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    FAM83D
  • Uniprot No.:
  • 別名:
    2310007D09Rik; BB104611; C20orf129; CHICA; dJ616B8.3; FA83D; FA83D_HUMAN; FAM83D; Family with sequence similarity 83; member D; FLJ38341; MGC92947; Protein FAM83D; RGD1565583; RP23-119H5.1; Spindle protein CHICA
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-585
  • 氨基酸序列
    MALLSEGLDE VPAACLSPCG PPNPTELFSE SRRLALEELV AGGPEAFAAF LRRERLARFL NPDEVHAILR AAERPGEEGA AAAAAAEDSF GSSHDCSSGT YFPEQSDLEP PLLELGWPAF YQGAYRGATR VETHFQPRGA GEGGPYGCKD ALRQQLRSAR EVIAVVMDVF TDIDIFRDLQ EICRKQGVAV YILLDQALLS QFLDMCMDLK VHPEQEKLMT VRTITGNIYY ARSGTKIIGK VHEKFTLIDG IRVATGSYSF TWTDGKLNSS NLVILSGQVV EHFDLEFRIL YAQSKPISPK LLSHFQSSNK FDHLTNRKPQ SKELTLGNLL RMRLARLSST PRKADLDPEM PAEGKAERKP HDCESSTVSE EDYFSSHRDE LQSRKAIDAA TQTEPGEEMP GLSVSEVGTQ TSITTACAGT QTAVITRIAS SQTTIWSRST TTQTDMDENI LFPRGTQSTE GSPVSKMSVS RSSSLKSSSS VSSQGSVASS TGSPASIRTT DFHNPGYPKY LGTPHLELYL SDSLRNLNKE RQFHFAGIRS RLNHMLAMLS RRTLFTENHL GLHSGNFSRV NLLAVRDVAL YPSYQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade. May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.
  • 基因功能參考文獻:
    1. FAM83D promotes HCC recurrence by promoting CD44 expression and CD44+ CSCs malignancy. PMID: 27769048
    2. Higher level of FAM83D expression is positively correlated with an increase in genome instability in many cancer. PMID: 26678035
    3. upregulation of FAM83D, a potential oncotarget gene, may be triggered by epigenetic events and can contribute to hepatocarcinogenesis PMID: 26125229
    4. NMR-derived secondary chemical shifts and relaxation properties show that the Chica LC8 binding domain is essentially disordered with a dynamically restricted segment in one linker between motifs. PMID: 26652654
    5. Taken together, these results demonstrate that FAM83D is a novel oncogene in HCC development and may constitute a potential therapeutic target in HCC. PMID: 25646692
    6. Results demonstrate that FAM83D has prognostic value for breast cancer patients and is a novel oncogene in breast cancer development that at least in part acts through mTOR hyper-activation by inhibiting FBXW7. PMID: 24344117
    7. interaction partner of the chromokinesin Kid that is required for the generation of polar ejection forces and chromosome congression PMID: 18485706

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族:
    FAM83 family
  • 組織特異性:
    Expressed in the testis.
  • 數據庫鏈接:

    HGNC: 16122

    KEGG: hsa:81610

    STRING: 9606.ENSP00000217429

    UniGene: Hs.726442



主站蜘蛛池模板: 宅男色影视亚洲人在线| 国产在线拍揄自揄拍免费下载| 国产成人无码午夜视频在线播放 | 4480yy私人精品国产| 一本大道大臿蕉视频无码| 欧美xxxx做受视频| 精品久久人人爽天天玩人人妻| 中文字幕无码日韩专区免费| 国产成人午夜福利在线播放 | 国产黑色丝袜视频在线观看网红| 欧美性黑人极品hd| 成人欧美一区二区三区的电影| 精品无人区一区二区三区| 久久亚洲色www成人男男| 人妻aⅴ中文字幕无码| 亚洲五月丁香综合视频| 少妇把腿扒开让我爽爽视频| 日本丰满熟妇乱子伦| 国产99在线 | 中国| 亚洲成av人无码综合在线观看 | 麻花豆传媒剧国产免费mv观看| 人妻巨大乳一二三区| 国产欧美日韩视频一区二区三区| 日本乱妇乱子视频| 国产免费永久精品无码| 中文字字幕在线中文乱码| 色六月婷婷亚洲婷婷六月| 精品无码人妻一区二区免费蜜桃| 免费人成视频x8x8入口| 亚洲性无码一区二区三区| 欧美精品久久96人妻无码| 欧美成人猛片aaaaaaa| 在线天堂新版最新版在线8 | 亚洲日产av中文字幕无码偷拍| 日韩人妻少妇一区二区三区| 夜夜欢天天干| 狠狠色噜噜狠狠狠888米奇视频 | 亚洲欧洲综合有码无码| 久久偷看各类wc女厕嘘嘘偷窃| 亚洲精品无码久久久久| 成人免费午夜无码视频在线播放|