在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protein CASC3 (CASC3)

Recombinant Human Protein CASC3 (CASC3)

  • 中文名稱：
    Recombinant Human Protein CASC3(CASC3)
  • 貨號：
    CSB-YP004535HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Protein CASC3(CASC3)
  • 貨號：
    CSB-EP004535HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Protein CASC3(CASC3)
  • 貨號：
    CSB-EP004535HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Protein CASC3(CASC3)
  • 貨號：
    CSB-BP004535HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Protein CASC3(CASC3)
  • 貨號：
    CSB-MP004535HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CASC3
  • Uniprot No.：
  • 別名：
    Barentsz; Barentsz protein; Btz; Cancer susceptibility candidate 3; Cancer susceptibility candidate gene 3 protein; CASC3; CASC3_HUMAN; Metastatic lymph node 51; Metastatic lymph node gene 51 protein; Metastatic lymph node protein 51; MLN 51; MLN 51 protein; MLN51; Protein barentsz; Protein CASC3; Protein MLN 51
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-703
  • 氨基酸序列
    MADRRRQRAS QDTEDEESGA SGSDSGGSPL RGGGSCSGSA GGGGSGSLPS QRGGRTGALH LRRVESGGAK SAEESECESE DGIEGDAVLS DYESAEDSEG EEGEYSEEEN SKVELKSEAN DAVNSSTKEE KGEEKPDTKS TVTGERQSGD GQESTEPVEN KVGKKGPKHL DDDEDRKNPA YIPRKGLFFE HDLRGQTQEE EVRPKGRQRK LWKDEGRWEH DKFREDEQAP KSRQELIALY GYDIRSAHNP DDIKPRRIRK PRYGSPPQRD PNWNGERLNK SHRHQGLGGT LPPRTFINRN AAGTGRMSAP RNYSRSGGFK EGRAGFRPVE AGGQHGGRSG ETVKHEISYR SRRLEQTSVR DPSPEADAPV LGSPEKEEAA SEPPAAAPDA APPPPDRPIE KKSYSRARRT RTKVGDAVKL AEEVPPPPEG LIPAPPVPET TPTPPTKTGT WEAPVDSSTS GLEQDVAQLN IAEQNWSPGQ PSFLQPRELR GMPNHIHMGA GPPPQFNRME EMGVQGGRAK RYSSQRQRPV PEPPAPPVHI SIMEGHYYDP LQFQGPIYTH GDSPAPLPPQ GMLVQPGMNL PHPGLHPHQT PAPLPNPGLY PPPVSMSPGQ PPPQQLLAPT YFSAPGVMNF GNPSYPYAPG ALPPPPPPHL YPNTQAPSQV YGGVTYYNPA QQQVQPKPSP PRRTPQPVTI KPPPPEVVSR GSS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). Stimulates the ATPase and RNA-helicase activities of EIF4A3. Plays a role in the stress response by participating in cytoplasmic stress granules assembly and by favoring cell recovery following stress. Component of the dendritic ribonucleoprotein particles (RNPs) in hippocampal neurons. May play a role in mRNA transport. Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions. Binds poly(G) and poly(U) RNA homomer.
  • 基因功能參考文獻：
    1. High CASC3 expression is associated with hepatocellular carcinoma. PMID: 27029030
    2. MLN51, alone or as part of the EJC, interacts directly with the pivotal eukaryotic translation initiation factor eIF3 PMID: 23530232
    3. MLN51 is a key factor in fibroblast-like synoviocyte hyperplasia of rheumatoid arthritis patients. PMID: 21327427
    4. data demonstrate that metastatic lymph node(MLN)51 protein associates with exon junction complex in the nucleus and remains stably associated with messenger RNA in the cytoplasm PMID: 15166247
    5. MLN51 is recruited into cytoplasmic aggregates known as stress granules (SGs) together with the SG-resident proteins. PMID: 17652158

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Nucleus speckle. Cytoplasm, Stress granule. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cell projection, dendrite.
  • 蛋白家族：
    CASC3 family
  • 組織特異性：
    Widely expressed. Overexpressed in breast cancers and metastasis, as well as in gastric cancers.
  • 數據庫鏈接：

    HGNC: 17040

    OMIM: 606504

    KEGG: hsa:22794

    STRING: 9606.ENSP00000264645

    UniGene: Hs.743287



主站蜘蛛池模板： 女人高潮被爽到呻吟在线观看| 久久久久亚洲精品成人网| 国产精品激情| 久久不见久久见中文字幕免费| 国产亚洲人成在线播放| 久久久久香蕉国产线看观看伊 | 亚洲人成网站日本片| 久久青草成人综合网站| 一本加勒比hezyo无码人妻| 午夜精品国产精品大乳美女| 无码av免费永久免费永久专区| 无码无套少妇18p在线直播| 午夜不卡无码中文字幕影院| av无码精品一区二区三区| 国精品人妻无码一区二区三区d3| 国产精品一区二区手机在线观看 | 亚洲欧美偷拍另类a∨| 欧洲熟妇色xxxx欧美老妇软件 | 丝袜老师办公室里做好紧好爽| 亚洲国产成av人天堂无码 | 特级毛片在线大全免费播放| 无码人妻在线一区二区三区免费 | 制服丝袜亚洲欧美中文字幕| 青青草av一区二区三区| 久9视频这里只有精品| 久久人搡人人玩人妻精品| 狼友av永久网站免费观看孕交| 久久99精品久久久久子伦| 国产精品成人观看视频| 人妻少妇久久中文字幕456| 成熟女人毛片www免费版在线| 最新亚洲人成无码网站| 大ji巴好深好爽又大又粗视频| 亚洲成av人片在线观看无| 中文成人在线| 久久久久欧美国产高潮| 国产成人综合亚洲看片| 亚洲精品国产suv| 在线人人车操人人看视频| 18禁止午夜福利体验区| 青青草原综合久久大伊人|