在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein BEX2 (BEX2)

  • 中文名稱:
    Recombinant Human Protein BEX2(BEX2)
  • 貨號(hào):
    CSB-YP883628HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Protein BEX2(BEX2)
  • 貨號(hào):
    CSB-EP883628HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Protein BEX2(BEX2)
  • 貨號(hào):
    CSB-EP883628HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Protein BEX2(BEX2)
  • 貨號(hào):
    CSB-BP883628HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Protein BEX2(BEX2)
  • 貨號(hào):
    CSB-MP883628HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    BEX2
  • Uniprot No.:
  • 別名:
    BEX2Protein BEX2; Brain-expressed X-linked protein 2; hBex2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    1-128
  • 氨基酸序列
    MESKEERALN NLIVENVNQE NDEKDEKEQV ANKGEPLALP LNVSEYCVPR GNRRRFRVRQ PILQYRWDIM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity.
  • 基因功能參考文獻(xiàn):
    1. The study reveals that BEX2 promotes colorectal cancer cell proliferation via the JNK/c-Jun pathway, suggesting BEX2 as a potential candidate target for the treatment of CRC. PMID: 28367093
    2. Bex2 affects the invasion and migration ability of glioma cells by regulating beta-catenin PMID: 25490384
    3. Bex2 overexpression promoted cell migration and invasion in glioma cell lines. PMID: 22907646
    4. Bex2 may be an important player during the development of glioma PMID: 23022184
    5. Both BEX2 and INI1/hSNF5 mainly localized in cell nucleus. PMID: 22698742
    6. BEX2 overexpression was associated with breast cancer. PMID: 21384344
    7. BEX2 has a functional interplay with c-Jun and p65/RelA in breast cancer. PMID: 20482821
    8. These results suggest that the conspicuous expression of the tumor suppressor genes BEX2, IGSF4 and TIMP3 in MLLmu acute myeloid leukemias cell lines is the consequence of altered epigenetic properties of MLL fusion proteins. PMID: 19835597
    9. hBex2 may act as a specific regulator during embryonic development by modulating the transcriptional activity of a novel E-box sequence-binding complex that contains hBex2, LMO2, NSCL2 and LDB1. PMID: 16314316
    10. Correlation between BEX2 expression and mixed lineage leukemia chromosomal aberrations are shown in the cell lines. PMID: 17251904
    11. a NGF/BEX2/NF-kappaB pathway is involved in regulating apoptosis in breast cancer cells and in modulating response to tamoxifen in primary tumors PMID: 17638883
    12. BEX2 is implicated in oligodendroglioma biology. PMID: 19412433

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    BEX family
  • 組織特異性:
    Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Widely expressed in breast cancer cell lines.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 30933

    OMIM: 300691

    KEGG: hsa:84707

    STRING: 9606.ENSP00000442521

    UniGene: Hs.398989



主站蜘蛛池模板: 亚洲国产av玩弄放荡人妇| 国产av国片精品一区二区| √最新版天堂资源网在线下载| 亚洲欧洲国产成人综合在线观看| 日本少妇毛茸茸高潮| 99久久无码私人网站| 中文字幕日韩精品亚洲一区| 中文字幕奈奈美被公侵犯| 国产av天堂亚洲国产av麻豆| 日日碰狠狠躁久久躁婷婷| 人人妻人人妻人人片av| 动漫无遮挡羞视频在线观看| 日本丰满护士爆乳xxxx| 精品一区二区av天堂| 永久免费看mv网站入口亚洲| 又大又粗又爽的少妇免费视频| 国产成人无码牲交免费视频 | 牲高潮99爽久久久久777| 好硬好湿好爽再深一点动态图视频| 国产三级av在线播放| 少妇无码av无码专区线| 七月丁香五月婷婷首页| 精品国模一区二区三区| 脱岳裙子从后面挺进去在线观看| 国产白丝无码免费视频| av人摸人人人澡人人超碰手机版 | 纯肉无遮挡无码日本动漫| 天堂av无码av在线a√| 国产精品久久久久久久久电影网| 国产成人a人亚洲精品无码| 国产传媒麻豆剧精品av| 成年入口无限观看免费完整大片| 亚洲色成人网一二三区| 国产精品自在线拍国产| 色情无码www视频无码区澳门 | 国产精品成人无码免费| 午夜免费视频| 777yyy亚洲精品久久久| 成人毛片18女人毛片免费| 潮喷失禁大喷水无码| 无码高潮又爽又黄a片日本动漫|