在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1 LLH PLOD)

  • 中文名稱:
  • 貨號:
    CSB-YP2411HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP2411HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP2411HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-BP2411HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-MP2411HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PLOD1
  • Uniprot No.:
  • 別名:
    Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; EC 1.14.11.4; Lysyl hydroxylase 1; LH1; PLOD1 LLH PLOD
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
  • 基因功能參考文獻:
    1. results indicated that PLOD1 is highly expressed in gastrointestinal carcinoma and is a potential prognostic marker and therapeutic target PMID: 29723071
    2. Ehlers Danlos syndrome in two children was confirmed by mutations in PLOD1 gene. Initially patients were thought to have either a diagnosis of classical EDS (cEDS) or a neuromuscular disorder due to absence of (congenital) scoliosis. PMID: 28757364
    3. Deficiency of the enzyme lysyl hydroxylase 1 (LH1) due to mutations in PLOD1 results in underhydroxylation of collagen lysyl residues and, hence, in the abnormal formation of collagen cross-links. PMID: 25277362
    4. Compared to slow progressing Alzheimer's disease, PLOD1 is upregulated in fast progressing Alzheimer's disease ;patients. PMID: 23234877
    5. Common polymorphisms in four candidate genes (COL11A1, COL18A1, FBN1 and PLOD1) were unlikely to play important roles in the genetic susceptibility to high myopia. PMID: 21527992
    6. Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity PMID: 11956192
    7. Results indicate that a C-terminal 40 amino acid segment of lysyl hydroxylase confers endoplasmic reticulum residency in a KDEL-receptor-independent manner. PMID: 12452796
    8. The results suggest that PLOD1 at 1p36, individually or in different combinations, contribute to osteoporosis susceptibility in Chinese. PMID: 19442614

    顯示更多

    收起更多

  • 相關疾病:
    Ehlers-Danlos syndrome 6 (EDS6)
  • 亞細胞定位:
    Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
  • 數據庫鏈接:

    HGNC: 9081

    OMIM: 153454

    KEGG: hsa:5351

    STRING: 9606.ENSP00000196061

    UniGene: Hs.75093



主站蜘蛛池模板: 国产精品无码无卡无需播放器| 中文字幕亚洲情99在线| 国产suv精品一区二区四| 四虎成人精品无码永久在线| 一区二区三区鲁丝不卡麻豆| 国产精品夜夜春夜夜爽久久| 亚洲精品无码不卡在线播放| 久久99精品国产麻豆宅宅| 国产亚洲情侣一区二区无| 国产萌白酱喷水视频在线播放| 亚洲风影视传媒有限公司辽宁| 亚洲乱码国产一区三区| 猫咪av成人永久网站在线观看| 人人婷婷人人澡人人爽| 国精产品一区一区三区免费视频 | 狠狠色噜噜狠狠狠8888米奇| 免费无码午夜福利片| 成年动漫18禁无码3d动漫 | 中文字幕人成乱码在线观看| 九九视频国产免| 手机在线亚洲国产精品| 亚洲一区二区三区| 亚洲一区av无码少妇电影| 亚洲大尺度无码无码专线| 亚洲高清国产拍精品26u| 激情综合色五月丁香六月欧美| 成人性生交大片免费看96| 欧美综合精品久久久久成人影院| 亚洲一区二区三区国产精品无码| 国产又黄又猛又粗又爽的a片动漫 成年女性特黄午夜视频免费看 | 东京热久久综合久久88| 久久久久久毛片免费播放| 国产av无码专区亚洲草草| 国产av天堂亚洲国产av天堂| 国产成人亚洲综合无码精品| 国产99视频精品免费专区| 99久e在线精品视频在线| 午夜福利无码不卡在线观看| www.-级毛片线天内射视视| 变态另类牲交乱| 人与性动交aaaabbbb|