在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1), partial

Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1), partial

  • 中文名稱：
    人GALNT1重組蛋白
  • 貨號：
    CSB-YP607410HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GALNT1重組蛋白
  • 貨號：
    CSB-EP607410HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GALNT1重組蛋白
  • 貨號：
    CSB-EP607410HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GALNT1重組蛋白
  • 貨號：
    CSB-BP607410HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GALNT1重組蛋白
  • 貨號：
    CSB-MP607410HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GALNT1
  • Uniprot No.：
  • 別名：
    GALNAC T1; GalNAc transferase 1; GalNAc-T1; GALNT 1; GALNT1; GALT1_HUMAN; Polypeptide GalNAc transferase 1; Polypeptide N acetylgalactosaminyltransferase 1; Polypeptide N-acetylgalactosaminyltransferase 1 soluble form; pp GaNTase 1; pp-GaNTase 1; Protein UDP acetylgalactosaminyltransferase 1; Protein-UDP acetylgalactosaminyltransferase 1; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 1; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1 (GalNAc T1); UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7.
  • 基因功能參考文獻：
    1. We have elucidated a novel miR-30-GALNT1/2 axis whose dysregulation increases the proportion of inactive proBNP secreted by the heart and impairs the compensatory actions of BNP during the progression of heart failure. PMID: 28188250
    2. the GalNAc-T13 isoform is predicted to function similarly to GalNAc-T1 against peptide substrates in vivo, in contrast to a prior report, but is unique by being selectively expressed in the brain. PMID: 27913570
    3. Expression of GALNT3 was reduced in CAD patients, and down regulation of GALNT3 contributed to endothelial injury by promoting apoptosis and up-regulating the expression of MMP-2 and MMP-14 genes via p38 MAPK activation. PMID: 26714046
    4. appears to be responsive to the inhibition of GALNT1 and SHH signaling PMID: 26676748
    5. Study demonstrates that down-regulation of GALNT1 is sufficient to suppress malignant phenotype of HCC cells by decreasing EGFR signaling. PMID: 25730904
    6. High ppGalNAc T1 expresdsion is associated with bladder cancer. PMID: 23317233
    7. The GALNT1 is the glycosyltransferase enzyme family covering a single known glycosidic linkage. PMID: 22183981
    8. Utilizing unnatural glycopeptide substrates for GalNAc-T3 we demonstrated that the GalNAc-specific sugar recognition of the lectin domain regulates further glycosylation. PMID: 22042768
    9. each ppGalNAc T isoform may be uniquely sensitive to peptide sequence and overall charge, which together dictates the substrate sites that will be glycosylated PMID: 21349845
    10. Growth factor stimulation regulates O-glycosylation initiation in a Src-dependent fashion by GalNac-T redistribution from golgi to the endoplasmic reticulum. PMID: 20498016
    11. the present analysis fails to replicate an earlier reported association of a GALNT1 variant with risk of ovarian cancer PMID: 20142253
    12. First simultaneous kinetic description of O-glycosylation events by recombinant UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase I at all putative O-glycosylation sites within human mucin MUC1 containing 5 tandem repeats. PMID: 14636048
    13. The results indicated that IL-4-treated LS174T cells are able to produce mucins with a higher degree of O-glycosylation than untreated counterparts. PMID: 17916404
    14. GalNAc T10 has a large and pronounced glycopeptide preference for Ser/Thr-O-GalNAc only at the +1 position from the acceptor site, whereas T1 and T2 have significantly reduced and variable preferences for Ser/Thr-O-GalNAc. PMID: 19460755
    15. A direct link between miR-129 and the two putative targets GALNT1 and SOX4 in bladder cancer. PMID: 19487295
    16. Data show that the sequences and O-glycosylation patterns direct the addition of the first and second sugar residues by ppGalNAc-T and C1GalT which act in a site directed fashion. PMID: 19524017

    顯示更多

    收起更多

  • 亞細胞定位：
    [Polypeptide N-acetylgalactosaminyltransferase 1]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.; [Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]: Secreted.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性：
    Widely expressed. Expressed in all tissues tested.
  • 數據庫鏈接：

    HGNC: 4123

    OMIM: 602273

    KEGG: hsa:2589

    STRING: 9606.ENSP00000269195

    UniGene: Hs.514806



主站蜘蛛池模板： 人妻人人看人妻人人添| 亚洲乱亚洲乱妇| 大香线蕉伊人超碰| 日本少妇浓毛bbwbbwbbw| 欧美日本日韩| 欧美老妇大p毛茸茸| 欧美又大又粗午夜剧场免费| 国内精品久久人妻无码网站| 亚洲高清国产拍精品闺蜜合租| 风间由美性色一区二区三区| 欧美两根一起进3p做受视频| 成年免费视频播放网站推荐| 人人做人人爽久久久精品| 精品卡1卡2卡三卡免费网站| 久久综合给合久久狠狠狠97色| 成人视频在线观看| 四虎成人欧美精品在永久在线| 丝袜美腿亚洲一区二区| 国产精品无码一区二区三区电影 | 中文幕无线码中文字蜜桃| 欧洲一卡2卡3卡4卡国产| 亚洲日韩成人无码不卡网站| 免费无码精品黄av电影| 国产97在线 | 日韩| 欧洲人免费视频网站在线| 免费无码又爽又刺激毛片| 天天躁夜夜躁av天天爽| 狠狠色丁香久久婷婷综合图片 | 东京热无码一区二区三区av| 在线观看成人无码中文av天堂| 日日躁夜夜躁狠狠躁超碰97| 亚洲一区二区三区在线观看网站| 久久99精品久久久久久hb亚瑟| 国产精品丝袜黑色高跟鞋| 久久综合九色综合欧美狠狠| 欧洲黑大粗无码免费| 少妇人妻丰满做爰xxx| 无码av天堂一区二区三区 | 东京热人妻无码一区二区av| 国产成人8x人网站视频在线观看| 野外亲子乱子伦视频丶|