在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Pleckstrin homology domain-containing family G member 6 (PLEKHG6)

Recombinant Human Pleckstrin homology domain-containing family G member 6 (PLEKHG6)

  • 中文名稱：
    人PLEKHG6重組蛋白
  • 貨號：
    CSB-YP664666HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PLEKHG6重組蛋白
  • 貨號：
    CSB-EP664666HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PLEKHG6重組蛋白
  • 貨號：
    CSB-EP664666HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PLEKHG6重組蛋白
  • 貨號：
    CSB-BP664666HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PLEKHG6重組蛋白
  • 貨號：
    CSB-MP664666HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PLEKHG6
  • Uniprot No.：
  • 別名：
    PLEKHG6; Pleckstrin homology domain-containing family G member 6; PH domain-containing family G member 6; Myosin-interacting guanine nucleotide exchange factor; MyoGEF
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-790
  • 氨基酸序列
    MKAFGPPHEG PLQGLVASRI ETYGGRHRAS AQSTAGRLYP RGYPVLDPSR RRLQQYVPFA RGSGQARGLS PMRLRDPEPE KRHGGHVGAG LLHSPKLKEL TKAHELEVRL HTFSMFGMPR LPPEDRRHWE IGEGGDSGLT IEKSWRELVP GHKEMSQELC HQQEALWELL TTELIYVRKL KIMTDLLAAG LLNLQRVGLL MEVSAETLFG NVPSLIRTHR SFWDEVLGPT LEETRASGQP LDPIGLQSGF LTFGQRFHPY VQYCLRVKQT MAYAREQQET NPLFHAFVQW CEKHKRSGRQ MLCDLLIKPH QRITKYPLLL HAVLKRSPEA RAQEALNAMI EAVESFLRHI NGQVRQGEEQ ESLAAAAQRI GPYEVLEPPS DEVEKNLRPF STLDLTSPML GVASEHTRQL LLEGPVRVKE GREGKLDVYL FLFSDVLLVT KPQRKADKAK VIRPPLMLEK LVCQPLRDPN SFLLIHLTEF QCVSSALLVH CPSPTDRAQW LEKTQQAQAA LQKLKAEEYV QQKRELLTLY RDQDRESPST RPSTPSLEGS QSSAEGRTPE FSTIIPHLVV TEDTDEDAPL VPDDTSDSGY GTLIPGTPTG SRSPLSRLRQ RALRRDPRLT FSTLELRDIP LRPHPPDPQA PQRRSAPELP EGILKGGSLP QEDPPTWSEE EDGASERGNV VVETLHRARL RGQLPSSPTH ADSAGESPWE SSGEEEEEGP LFLKAGHTSL RPMRAEDMLR EIREELASQR IEGAEEPRDS RPRKLTRAQL QRMRGPHIIQ LDTPLSASEV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
  • 基因功能參考文獻：
    1. Intramolecular interactions between MyoGEF domains act as an autoinhibitory mechanism for the regulation of MyoGEF functions. PMID: 25336641
    2. Taken together, these results suggest that aurora B coordinates with Plk1 to regulate MyoGEF activation and localization, thus contributing to the regulation of cytokinesis. PMID: 24482237
    3. GIPC1-MyoGEF complex formation plays an important role in regulating MDA-MB-231 breast cancer cell polarization and invasion. PMID: 20634288
    4. ezrin allows the local activation of RhoG at the apical pole of epithelial cells by recruiting upstream and downstream regulators of RhoG and that both PLEKHG6 and ezrin are required for efficient macropinocytosis PMID: 17881735
    5. Plk1 can regulate MyoGEF activity and localization, contributing to the regulation of cytokinesis PMID: 18694934
    6. MyoGEF cooperates with nonmuscle myosin IIA to regulate the polarity and invasion activity of breast cancer cells through activation of RhoA and RhoC. PMID: 19421144

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, microvillus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cleavage furrow.
  • 組織特異性：
    Highest expression in the placenta. Low levels in small intestine, lung, liver, kidney, thymus and heart.
  • 數據庫鏈接：

    HGNC: 25562

    OMIM: 611743

    KEGG: hsa:55200

    STRING: 9606.ENSP00000011684

    UniGene: Hs.631660



主站蜘蛛池模板： 亚洲天堂2017无码| 亚洲精品少妇30p| 无码人妻精品一区二区蜜桃百度| 亚洲黑人巨大videos| 野花在线无码视频在线播放| 国产免费人成视频在线播放播 | 天天操夜夜操| 天天躁夜夜躁狠狠躁2021| 亚洲成av人片天堂网无码】| 日韩夜夜高潮夜夜爽无码| 国产高清视频一区三区| 亚洲youwu永久无码精品| 国产成人精品手机在线观看| 黑人大荫蒂老太大| 亚洲国产精品无码专区| 中文av伊人av无码av狼人| 精品无码国产自产拍在线观看| 性xxxx搡xxxxx搡欧美| av天堂永久资源网亚洲高清| 欧美成人天天综合在线| 老熟女高潮喷水了| 国产毛多水多高潮高清| 欧美激情猛片xxxⅹ大3| 99精品国产一区二区三区a片 | 日本中文字幕乱码aa高清电影| 中文在线www天堂网| 亚洲日本va午夜中文字幕一区| 成人国产mv免费视频| 亚洲大片av毛片免费| 美女视频黄频a美女大全| 亚洲男女羞羞无遮挡久久丫| 亚洲成a人v欧美综合天堂下载| 综合亚洲综合图区网友自拍| 国偷自产av一区二区三区| 国产免费啪嗒啪嗒视频看看| 婷婷综合缴情亚洲| 国产精品美女久久久久久久久| 久久中文字幕人妻av熟女| 国产熟妇精品高潮一区二区三区| 久久午夜羞羞影院免费观看| 国产一区二区三区四区五区vm|