在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Pleckstrin homology domain-containing family F member 2 (PLEKHF2)

  • 中文名稱:
    人PLEKHF2重組蛋白
  • 貨號:
    CSB-YP884492HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PLEKHF2重組蛋白
  • 貨號:
    CSB-EP884492HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PLEKHF2重組蛋白
  • 貨號:
    CSB-BP884492HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PLEKHF2重組蛋白
  • 貨號:
    CSB-MP884492HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    110070J07Rik; AA673237; FLJ13187; PH and FYVE domain containing protein 2; PH and FYVE domain-containing protein 2; PH domain containing family F member 2; PH domain-containing family F member 2; Phafin 2; Phafin-2; PHAFIN2; PKHF2_HUMAN; pleckstrin homology domain containing, family F (with FYVE domain) member 2; pleckstrin homology domain containing, family F (with FYVE domain) member2 ; Pleckstrin homology domain-containing family F member 2; Plekhf2; ZFYVE18; Zinc finger FYVE domain containing protein 18 ; Zinc finger FYVE domain-containing protein 18
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-249
  • 氨基酸序列
    MVDRLANSEA NTRRISIVEN CFGAAGQPLT IPGRVLIGEG VLTKLCRKKP KARQFFLFND ILVYGNIVIQ KKKYNKQHII PLENVTIDSI KDEGDLRNGW LIKTPTKSFA VYAATATEKS EWMNHINKCV TDLLSKSGKT PSNEHAAVWV PDSEATVCMR CQKAKFTPVN RRHHCRKCGF VVCGPCSEKR FLLPSQSSKP VRICDFCYDL LSAGDMATCQ PARSDSYSQS LKSPLNDMSD DDDDDDSSD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
  • 基因功能參考文獻:
    1. PtdIns(3)P binding to Phafin2 occurs with high affinity, triggering minor conformational changes in the protein. Taken together, these studies represent a platform for establishing the structural basis of Phafin2 molecular interactions and the role of the two potentially redundant PtdIns(3)P-binding domains of the protein in endomembrane compartments. PMID: 28152563
    2. These findings establish that lysosomal accumulation of Akt and Phafin2 is a critical step in the induction of autophagy via an interaction with phosphatidylinositol 3 phosphate. PMID: 24416124
    3. Phafin2 controls EGFR trafficking through early endosomes by facilitating endosome fusion in concert with EEA1. PMID: 22816767
    4. These results provide a vivid example that an endosome modulator, such as Phafin2, may control the cells' responses to the extracellular cues. PMID: 19995552
    5. Results demonstrate that EAPF/Phafin-2 facilitates TNF-alpha-induced cellular apoptosis through an ER-mitochondrial apoptotic pathway. PMID: 18288467

    顯示更多

    收起更多

  • 亞細胞定位:
    Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum.
  • 組織特異性:
    Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells.
  • 數據庫鏈接:

    HGNC: 20757

    OMIM: 615208

    KEGG: hsa:79666

    STRING: 9606.ENSP00000322373

    UniGene: Hs.29724



主站蜘蛛池模板: 99国产精品人妻噜啊噜| 强插女教师av在线| 亚洲欧美日韩国产综合在线一区 | aaa午夜级特黄日本大片| 亚洲成av人片在线观看高清| 韩国v欧美v亚洲v日本v| 少妇高潮灌满白浆毛片免费看| 久久久婷婷五月亚洲97号色 | 亚洲日韩精品射精日| 鲁一鲁一鲁一鲁一曰综合网| 免费精品国产自在| 亚洲国产精品久久久久久无码 | 久久久日韩精品一区二区三区| 久久婷婷五月综合97色一本一本| 亚在线观看免费视频入口| 国内精品久久久久久久影视| 免费毛片手机在线播放| 免费国产污网站在线观看| 亚洲国产精品va在线看黑人| 丁香五香天堂网| 国产午费午夜福利200集| 国语对白做受xxxxx在| 日本xxxxx片免费观看喷水| 青青草原综合久久大伊人| 国产成人精品综合在线观看| 久久人妻无码aⅴ毛片a片app| 少妇无码av无码一区| 人妻少妇av中文字幕乱码| 巨大黑人极品videos精品| 亚洲国产精品日韩av不卡在线| 精品一卡2卡三卡4卡乱码精品视频| 无码人妻精品一区二区三区蜜桃| 一区二区亚洲精品国产精华液| 国产乱码日产精品bd| 天堂va视频一区二区| 国产欧美精品区一区二区三区| 欧美丰满熟妇xxxxx| 亚洲人成电影网站色迅雷| 加勒比中文无码久久综合色| 欧美顶级少妇做爰hd| 日韩无码电影|