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  4. Recombinant Human Phospholipase B1, membrane-associated (PLB1), partial

Recombinant Human Phospholipase B1, membrane-associated (PLB1), partial

  • 中文名稱(chēng)：
    人PLB1重組蛋白
  • 貨號(hào)：
    CSB-YP761273HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    人PLB1重組蛋白
  • 貨號(hào)：
    CSB-EP761273HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    人PLB1重組蛋白
  • 貨號(hào)：
    CSB-EP761273HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    人PLB1重組蛋白
  • 貨號(hào)：
    CSB-BP761273HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    人PLB1重組蛋白
  • 貨號(hào)：
    CSB-MP761273HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    PLB1; PLB; Phospholipase B1; membrane-associated; Phospholipase B; hPLB; Phospholipase B/lipase; PLB/LIP) [Includes: Phospholipase A2; EC 3.1.1.4); Lysophospholipase; EC 3.1.1.5)]
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity). Has dual phospholipase and lysophospholipase activities toward diacylphospholipids. Preferentially cleaves sn-2 ester bonds over sn-1 bonds. Acts as a lipase toward glycerolipid substrates. Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity. May also hydrolyze long chain retinyl esters such as retinyl palmitate. May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border.
  • 基因功能參考文獻(xiàn)：
    1. rs117512489 in gene phospholipase B1 gene is associated with Non-Small Cell Lung Cancer. PMID: 28104536
    2. PLB1 is a candidate risk gene for rheumatoid arthritis. PMID: 24520335
    3. identification of epidermis as a site of expression PMID: 12150957
  • 亞細(xì)胞定位：
    Apical cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    'GDSL' lipolytic enzyme family, Phospholipase B1 subfamily
  • 組織特異性：
    Expressed in the epidermis (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30041

    OMIM: 610179

    KEGG: hsa:151056

    STRING: 9606.ENSP00000330442

    UniGene: Hs.444933



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