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  4. Recombinant Human Phosphatidylcholine transfer protein (PCTP)

Recombinant Human Phosphatidylcholine transfer protein (PCTP)

  • 中文名稱：
    人PCTP重組蛋白
  • 貨號：
    CSB-YP017651HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PCTP重組蛋白
  • 貨號：
    CSB-EP017651HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PCTP重組蛋白
  • 貨號：
    CSB-EP017651HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PCTP重組蛋白
  • 貨號：
    CSB-BP017651HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PCTP重組蛋白
  • 貨號：
    CSB-MP017651HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PCTP
  • Uniprot No.：
  • 別名：
    PC TP; PC-TP; PCTP; Phosphatidylcholine transfer protein; PPCT_HUMAN; StAR related lipid transfer (START) domain containing 2; StAR related lipid transfer protein 2; StAR-related lipid transfer protein 2; STARD 2; StARD2; START domain containing 2; START domain containing protein 2; START domain-containing protein 2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-214
  • 氨基酸序列
    MELAAGSFSE EQFWEACAEL QQPALAGADW QLLVETSGIS IYRLLDKKTG LYEYKVFGVL EDCSPTLLAD IYMDSDYRKQ WDQYVKELYE QECNGETVVY WEVKYPFPMS NRDYVYLRQR RDLDMEGRKI HVILARSTSM PQLGERSGVI RVKQYKQSLA IESDGKKGSK VFMYYFDNPG GQIPSWLINW AAKNGVPNFL KDMARACQNY LKKT
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule.
  • 基因功能參考文獻：
    1. Identified the variant rs2912553 as contributing to racially differential expression of PCTP. PMID: 28251237
    2. Mutations in PCTP gene is associated with prostate cancer PMID: 26585945
    3. PC-TP contributes to the racial difference in PAR4-mediated platelet activation. PMID: 24216752
    4. crystal structures of human PC-TP in complex with dilinoleoyl-PtdCho or palmitoyl-linoleoyl-PtdCho reveal that a single well-ordered PtdCho molecule occupies a centrally located tunnel PMID: 12055623
    5. phosphatidylcholine transfer protein gene variants are associated with LDL-peak particle size PMID: 17266964

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  • 亞細胞定位：
    Cytoplasm.
  • 組織特異性：
    Highest expression in liver, placenta, testis, kidney and heart. Low levels in brain and lung. No expression detected in thymus.
  • 數據庫鏈接：

    HGNC: 8752

    OMIM: 606055

    KEGG: hsa:58488

    STRING: 9606.ENSP00000268896

    UniGene: Hs.285218



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