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  4. Recombinant Human Peroxiredoxin-like 2A (PRXL2A)

Recombinant Human Peroxiredoxin-like 2A (PRXL2A)

  • 中文名稱：
    人FAM213A重組蛋白
  • 貨號(hào)：
    CSB-YP883589HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人FAM213A重組蛋白
  • 貨號(hào)：
    CSB-EP883589HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人FAM213A重組蛋白
  • 貨號(hào)：
    CSB-BP883589HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人FAM213A重組蛋白
  • 貨號(hào)：
    CSB-MP883589HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FAM213A
  • Uniprot No.：
  • 別名：
    C10orf58; CJ058_HUMAN; UPF0765 protein C10orf58
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-229
  • 氨基酸序列
    MSFLQDPSFF TMGMWSIGAG ALGAAALALL LANTDVFLSK PQKAALEYLE DIDLKTLEKE PRTFKAKELW EKNGAVIMAV RRPGCFLCRE EAADLSSLKS MLDQLGVPLY AVVKEHIRTE VKDFQPYFKG EIFLDEKKKF YGPQRRKMMF MGFIRLGVWY NFFRAWNGGF SGNLEGEGFI LGGVFVVGSG KQGILLEHRE KEFGDKVNLL SVLEAAKMIK PQTLASEKK
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.
  • 基因功能參考文獻(xiàn)：
    1. Antioxidant stress induces PAMM mRNA expression in human peripheral blood mononuclear cells . PMID: 26402163
    2. results suggest that adipocyte-derived PAMM may suppress macrophage activation by inhibiting MAPK signalling pathway. PMID: 26438880
    3. The PAMM is a redox regulatory protein that modulates osteoclast differentiation in vitro. PAMM expression may affect bone resorption in vivo and help to maintain bone mass. PMID: 19951071
  • 亞細(xì)胞定位：
    Cytoplasm. Secreted.
  • 蛋白家族：
    Peroxiredoxin-like FAM213 family, FAM213A subfamily
  • 組織特異性：
    Expressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 28651

    OMIM: 617165

    KEGG: hsa:84293

    STRING: 9606.ENSP00000361254

    UniGene: Hs.500333



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