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  4. Recombinant Human Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3)

Recombinant Human Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3)

  • 中文名稱：
    人PPIL3重組蛋白
  • 貨號：
    CSB-YP863962HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PPIL3重組蛋白
  • 貨號：
    CSB-EP863962HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PPIL3重組蛋白
  • 貨號：
    CSB-EP863962HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PPIL3重組蛋白
  • 貨號：
    CSB-BP863962HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PPIL3重組蛋白
  • 貨號：
    CSB-MP863962HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    2310076N22Rik; 2510026K04Rik; Ccyclophilin like protein; Cyclophilin J; Cyclophilin like 3; Cyclophilin like protein 3; Cyclophilin like protein PPIL3; Cyclophilin-like protein PPIL3; Cyp10l; CyPJ; MGC105285; Peptidyl prolyl cis trans isomerase like 3; Peptidyl-prolyl cis-trans isomerase-like 3; Peptidylprolyl cis trans isomerase like protein 3; Peptidylprolyl isomerase (cyclophilin) like 3; Peptidylprolyl isomerase like 3; PPIase; PPIase like protein 3; Ppil3; PPIL3_HUMAN; Rotamase; Rotamase PPIL3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-161
  • 氨基酸序列
    SVTLHTDVG DIKIEVFCER TPKTCENFLA LCASNYYNGC IFHRNIKGFM VQTGDPTGTG RGGNSIWGKK FEDEYSEYLK HNVRGVVSMA NNGPNTNGSQ FFITYGKQPH LDMKYTVFGK VIDGLETLDE LEKLPVNEKT YRPLNDVHIK DITIHANPFA Q
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.
  • 基因功能參考文獻：
    1. Cyclophilin J expression was up-regulated in gastric carcinoma compared to normal gastric tissues. PMID: 28739742
    2. CYPJ structurally resembles CYPA. It is sensitive to inhibition by CsA and plays a role in regulating cell growth, proliferation, and apoptosis. PMID: 26977013
    3. Suppression of CYPJ could repress the growth of HCC, which makes CYPJ a potential target for the development of new strategies to treat this malignancy. PMID: 26020957
    4. The novel full-length gene of human PPIL3 may be correlated with the formation of human glioma. PMID: 15989758
    5. Human cyclophilin J, a new member of the cyclophilin family, has been expressed and crystallized. PMID: 16510998
    6. Human peptidyl-prolyl isomerase-like 3 (Ppil3) is one of the Apoptin-associated proteins. PMID: 18474220

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  • 蛋白家族：
    Cyclophilin-type PPIase family, PPIL3 subfamily
  • 組織特異性：
    Ubiquitous. Detected at low levels.
  • 數據庫鏈接：

    HGNC: 9262

    OMIM: 615811

    KEGG: hsa:53938

    UniGene: Hs.121076



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