在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Peptide deformylase, mitochondrial (PDF)

Recombinant Human Peptide deformylase, mitochondrial (PDF)

  • 中文名稱：
    人PDF重組蛋白
  • 貨號：
    CSB-YP872538HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PDF重組蛋白
  • 貨號：
    CSB-EP872538HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PDF重組蛋白
  • 貨號：
    CSB-BP872538HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PDF重組蛋白
  • 貨號：
    CSB-MP872538HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PDF
  • Uniprot No.：
  • 別名：
    PDF; PDF1A; Peptide deformylase; mitochondrial; EC 3.5.1.88; Polypeptide deformylase
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    40-243
  • 氨基酸序列
    E GPALRRSYWR HLRRLVLGPP EPPFSHVCQV GDPVLRGVAA PVERAQLGGP ELQRLTQRLV QVMRRRRCVG LSAPQLGVPR QVLALELPEA LCRECPPRQR ALRQMEPFPL RVFVNPSLRV LDSRLVTFPE GCESVAGFLA CVPRFQAVQI SGLDPNGEQV VWQASGWAAR IIQHEMDHLQ GCLFIDKMDS RTFTNVYWMK VND
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Removes the formyl group from the N-terminal Met of newly synthesized proteins.
  • 基因功能參考文獻(xiàn)：
    1. compound M7594_0037 exhibited potent anticancer activities against HeLa, A549 and MCF-7 cell lines with IC50s of 35.26, 29.63 and 24.63 muM, respectively. Molecular docking studies suggested that M7594_0037 and its three derivatives could interact with Human peptide deformylase by several conserved hydrogen bonds. PMID: 27023495
    2. c-myc regulated the expression of human PDF. PMID: 24675470
    3. This is the first report showing that PDF is over-expressed in breast, colon, and lung cancers PMID: 23815882
    4. these data reveals that PDF has several transcription start sites, the most important of which only 18 bp from the initiation codon. PMID: 22554513
    5. the origin, evolution and preservation of the COG8/PDF same-strand overlap follow similar mechanistic steps as those documented for antisense overlaps where gain and/or loss of splice sites and polyadenylation signals seems to drive the process. PMID: 21805148
    6. The inhibition of HsPDF may provide an explanation for the mechanism by which actinonin is cytotoxic against various human tumor cell lines. PMID: 14637138
    7. Despite the lack of true S2' and S3' binding pockets, confirmed through peptide binding modeling, enzyme kinetics suggest a combined contribution from P2'and P3' positions of a formylated peptide substrate to turnover. PMID: 19236878

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    Polypeptide deformylase family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30012

    KEGG: hsa:64146

    STRING: 9606.ENSP00000288022

    UniGene: Hs.130849



主站蜘蛛池模板： 国产无套内射普通话对白| 99久久国产亚洲高清观看| 少妇无码av无码一区| 最新在线精品国自产拍视频| 午夜丰满少妇性开放视频| 无码中文字幕日韩专区视频| 久久久无码人妻精品无码| 国产精品白丝av在线观看播放| 国产+成+人+亚洲欧洲自线| 在线a久青草视频在线观看 | 久久人人爽人人爽人人片av高清| 国产精品一品二区三区的使用体验| 爆爽久久久一区二区又大又黄又嫩| 日产精品卡二卡三卡四卡乱码视频| 欧洲丰满少妇a毛片| 少妇的丰满人妻hd高清| 人妻丰满熟妇av无码区免| 亚洲乱亚洲乱妇中文影视| 变态另类牲交乱| 狠狠色丁香久久婷婷综合蜜芽五月 | 丰满少妇人妻无码专区| 99这里只有精品| 成人午夜亚洲精品无码区毛片| 在线观看的av免费网站| 久久亚洲熟女cc98cm| 欧洲亚洲色一区二区色99| 免费国产va在线观看| 秋秋影视午夜福利高清| 无码一区二区三区av在线播放| 玩弄japan白嫩少妇hd小说| 精产国品一二三产区蘑菇视频| 西西人体大胆扒开下部337卩| 欧美写真视频在线观看| 精品少妇人妻av免费久久久| 国产日产欧产精品精品| 亚洲手机在线人成网站| 精品人妻少妇一区二区三区| 少妇又紧又色又爽又刺激视频| 天堂在线www资源在线| 日韩精品久久久久久免费| 国产精品无码无需播放器|