在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Pancreatic secretory granule membrane major glycoprotein GP2 (GP2)

Recombinant Human Pancreatic secretory granule membrane major glycoprotein GP2 (GP2)

  • 中文名稱：
    人GP2重組蛋白
  • 貨號：
    CSB-YP009687HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GP2重組蛋白
  • 貨號：
    CSB-EP009687HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GP2重組蛋白
  • 貨號：
    CSB-EP009687HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GP2重組蛋白
  • 貨號：
    CSB-BP009687HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GP2重組蛋白
  • 貨號：
    CSB-MP009687HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    DKFZp779K0533; Glycoprotein 2 (zymogen granule membrane); GP2; GP2_HUMAN; Pancreatic secretory granule membrane major glycoprotein GP2; Pancreatic zymogen granule membrane associated protein GP2; Pancreatic zymogen granule membrane protein GP-2; ZAP75
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    29-512
  • 氨基酸序列
    VQ RGYGNPIEAS SYGLDLDCGA PGTPEAHVCF DPCQNYTLLD EPFRSTENSA GSQGCDKNMS GWYRFVGEGG VRMSETCVQV HRCQTDAPMW LNGTHPALGD GITNHTACAH WSGNCCFWKT EVLVKACPGG YHVYRLEGTP WCNLRYCTVP RDPSTVEDKC EKACRPEEEC LALNSTWGCF CRQDLNSSDV HSLQPQLDCG PREIKVKVDK CLLGGLGLGE EVIAYLRDPN CSSILQTEER NWVSVTSPVQ ASACRNILER NQTHAIYKNT LSLVNDFIIR DTILNINFQC AYPLDMKVSL QAALQPIVSS LNVSVDGNGE FIVRMALFQD QNYTNPYEGD AVELSVESVL YVGAILEQGD TSRFNLVLRN CYATPTEDKA DLVKYFIIRN SCSNQRDSTI HVEENGQSSE SRFSVQMFMF AGHYDLVFLH CEIHLCDSLN EQCQPSCSRS QVRSEVPAID LARVLDLGPI TRRGAQSPGV MN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Functions as an intestinal M-cells transcytotic receptor specific of type-I-piliated bacteria that participate in the mucosal immune response toward these bacteria. At the apical membrane of M-cells binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to ellicit a mucosal immune response.
  • 基因功能參考文獻：
    1. Data indicate the secretory granule membrane glycoprotein 2 as a marker for PDX1+/NKX6-1+ pancreatic progenitors (PPs). PMID: 28835709
    2. Totals of 12.4% and 20.8% of Crohn's disease patients were positive for IgA/IgG type of anti-GP2 and anti-CUZD1, respectively. Positivity for anti-pancreatic autoantibodies predicted a faster progression towards complicated disease course. PMID: 25968583
    3. Anti-GP2 antibody positive CD patients had higher ASCA titres compared to seronegative cases. PMID: 23118780
    4. A novel role for GP2 in immune regulation could provide a platform for new therapeutic interventions in the treatment of Crohn disease. PMID: 22891285
    5. GP2 is a binding partner of the scavenger receptor expressed on endothelial cells I (SREC-I) but not of SR-AI and SR-BI. Dendritic cells express SREC-I and also bind and internalize GP2. PMID: 21190681
    6. GP2 gene is unlikely to play a major role in the etiology of chronic pancreatitis. PMID: 20335779
    7. Data suggest that GP2 alterations do not alter the risk for the development of chronic pancreatitis. PMID: 19959969
    8. This study represents the first detailed analysis of any variation in the GP2 gene and gives some support to the putative association of c.1275A>G with chronic pancreatitis disease protection. PMID: 19919903
    9. GP2 binds to Type 1 fimbria, a bacterial adhesin that is commonly expressed by members of the Enterobacteriacae family. PMID: 19627615
    10. glycoprotein 2 (GP2), specifically expressed on the apical plasma membrane of M cells among enterocytes, serves as a transcytotic receptor for mucosal antigens PMID: 19907495
    11. According to human genome blasts for Build 35.1, this gene is located on 16p12 not 9q21 as described in this paper. PMID: 9605860

    顯示更多

    收起更多

  • 亞細胞定位：
    Zymogen granule membrane; Lipid-anchor, GPI-anchor. Secreted. Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane; Lipid-anchor, GPI-anchor. Membrane raft; Lipid-anchor, GPI-anchor. Endosome.
  • 組織特異性：
    Expressed in pancreas (at protein level). Specifically expressed by M (microfold) cells which are atypical epithelial cells of the intestine (at protein level).
  • 數據庫鏈接：

    HGNC: 4441

    OMIM: 602977

    KEGG: hsa:2813

    STRING: 9606.ENSP00000370767

    UniGene: Hs.53985



主站蜘蛛池模板： 婷婷色五月开心五月| 国内精品国产成人国产三级| 国精品人妻无码一区二区三区喝尿| 国产欧美精品一区二区三区-老狼| 日韩国产高清一区二区| 久久亚洲精品情侣| 熟女丝袜潮喷内裤视频网站| 亚洲色欲色欲www在线看| 日韩免费视频| 国产高清成人免费视频在线观看| 成人无码www在线看免费| 亚洲大色堂人在线无码| 一边摸一边叫床一边爽av| 国产日产久久高清欧美一区| 久久婷婷五月综合色丁香| 人人爽久久涩噜噜噜av| h漫全彩纯肉无码网站| 国产精品无套呻吟在线| 国产精品自在在线午夜出白浆| 亚洲熟女乱综合一区二区在线| av区无码字幕中文色| 在线观看国产精品普通话对白精品| yy111111少妇无码影院| 久久综合色之久久综合| 午夜美女裸体福利视频| 亚洲欧美成人久久一区| 亚洲学生妹高清av| 久久妇女高潮喷水多| 成年女人免费v片| 日产精品卡2卡三卡乱码网站| 少妇高潮大叫好爽| 9l国产精品久久久久尤物| 中国女人大白屁股ass| 免费两性的视频网站| 日韩99在线 | 中文| 无套中出极品少妇白浆| 好大好湿好硬顶到了好爽视频| 成人亚洲一区无码久久| 国产精品久久人妻无码| 欧美 变态 另类 人妖| 国产高清亚洲精品视bt天堂频|