在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human PRELI domain-containing protein 1, mitochondrial (PRELID1)

In Stock
  • 中文名稱:
    人PRELID1重組蛋白
  • 貨號:
    CSB-EP896867HU
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    PRELID1
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    33.9 kDa
  • 表達區域:
    36-219aa
  • 氨基酸序列
    TEDIVHREVTPDQKLLSRRLLTKTNRMPRWAERLFPANVAHSVYVLEDSIVDPQNQTMTTFTWNINHARLMVVEERCVYCVNSDNSGWTEIRREAWVSSSLFGVSRAVQEFGLARFKSNVTKTMKGFEYILAKLQGEAPSKTLVETAKEAKEKAKETALAATEKAKDLASKAATKKQQQQQQFV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-SUMO-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.
  • 基因功能參考文獻:
    1. This study suggests that the regulation of PRELID1 expression, by alternative polyadenylation and other mechanisms, plays a role in mitochondrial ROS signaling and represents a novel prognostic factor and therapeutic target in cancer PMID: 28912168
    2. PRELI plays an important role in the suppression of apoptosis in HepG2 cells in response to oxidative stress. PMID: 26275693
    3. Loss of TRIAP1 or PRELI impairs the accumulation of Cardiolipin, facilitates the release of cytochrome c, and renders cells vulnerable to apoptosis upon intrinsic and extrinsic stimulation. PMID: 23931759
    4. PRELI is a vital LEA B cell protein with failsafe genetics PMID: 22666421
    5. PRELI interacts with OPA1 to maintain mitochondria structures intact, sustain balanced ion(-)/proton(+) gradients, promote oxidative phosphorylation reactions, regulate pro- and antiapoptotic protein traffic and enable cell responses to induced death. PMID: 21364629

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion. Mitochondrion intermembrane space.
  • 組織特異性:
    Highly expressed in fetal liver; less expressed in fetal brain, lung, and kidney. At the adult stage, expression is drastically reduced in the liver but highly expressed in the spleen, brain, lung, lymph nodes and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 30255

    OMIM: 605733

    KEGG: hsa:27166

    STRING: 9606.ENSP00000302114

    UniGene: Hs.744904



主站蜘蛛池模板: 亚洲卡1卡2卡新区网站| 内射人妻无码色ab麻豆| 久久精品国产精品国产精品污| 精品国产欧美一区二区| 青草内射中出高潮| 国产精品亚洲五月天高清| 久久亚洲日韩av一区二区三区| 亚洲国产精品一区二区制服| 性欧美老妇另类xxxx| 免费无码在线播放av| 亚洲 欧洲 日韩 综合av| 亚洲一区二区三区四区| 99精品无人区乱码在线观看| 欧美亚洲偷图色综合| 天堂√最新版中文在线天堂| 日韩99在线 | 中文| 屁屁影院ccyy备用地址| 97在线视频人妻无码| 欧美大屁股流白浆xxxx| 99视频精品全部免费免费观看| 女人与牲口性恔配视频免费| 国产精品免费久久久久软件| 久久免费看少妇高潮v片特黄| 精品久久亚洲中文无码| 两个人日本www免费版| 国产传媒麻豆剧精品av国产| 亚洲精品国男人在线视频| 国产男女猛烈无遮挡免费视频| 国产网友自拍在线视频| 在线 | 麻豆国产传媒61国产免费 视频在线+欧美十亚洲曰本 | 色妞ww精品视频7777| 成人aaa片一区国产精品| 极品尤物被啪到呻吟喷水| 久久精品国产99久久丝袜蜜桃| 4480yy私人精品国产| 99久久国产综合精品五月天喷水| 无码少妇一区二区三区| 青青国产线免观| 久久国产精品99久久久久久口爆| 99这里有精品视频视频| 国产精品久久久|