在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Nitric oxide synthase-interacting protein (NOSIP)

Recombinant Human Nitric oxide synthase-interacting protein (NOSIP)

  • 中文名稱：
    人NOSIP重組蛋白
  • 貨號：
    CSB-YP897477HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人NOSIP重組蛋白
  • 貨號：
    CSB-EP897477HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人NOSIP重組蛋白
  • 貨號：
    CSB-EP897477HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人NOSIP重組蛋白
  • 貨號：
    CSB-BP897477HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人NOSIP重組蛋白
  • 貨號：
    CSB-MP897477HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NOSIP
  • Uniprot No.：
  • 別名：
    NOSIP; CGI-25; Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase NOSIP; EC 2.3.2.27; RING-type E3 ubiquitin transferase NOSIP; eNOS-interacting protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-301
  • 氨基酸序列
    MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QNIRLSRDAV KDFDCCCLSL QPCHDPVVTP DGYLYEREAI LEYILHQKKE IARQMKAYEK QRGTRREEQK ELQRAASQDH VRGFLEKESA IVSRPLNPFT AKALSGTSPD DVQPGPSVGP PSKDKDKVLP SFWIPSLTPE AKATKLEKPS RTVTCPMSGK PLRMSDLTPV HFTPLDSSVD RVGLITRSER YVCAVTRDSL SNATPCAVLR PSGAVVTLEC VEKLIRKDMV DPVTGDKLTD RDIIVLQRGG TGFAGSGVKL QAEKSRPVMQ A
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
  • 基因功能參考文獻：
    1. While NOSIP expression was increased in Hirschsprung's disease (HSCR) vs. non- HSCR patients, no significant difference was observed in patients with Hirschsprung's associated enterocolitis. The increased expression of NOSIP in the aganglionic and ganglionic bowel of HSCR may contribute to the development of enterocolitis by inhibiting local nitric oxide production in patients with Hirschsprung's disease. PMID: 28196663
    2. Endogenous NOSIP reduces the enzymatic capacity of eNOS, specifically in the G(2) phase of the cell cycle by targeting eNOS to the actin cytoskeleton. PMID: 16135813
    3. endothelial nitric oxide synthase (eNOS) interacting protein (NOSIP), modulator of eNOS activity by alteration of eNOS subcellular localisation; high expression levels in endothelial cells and vascularized tissue. PMID: 11149895
  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle (PubMed:16135813).
  • 蛋白家族：
    NOSIP family
  • 組織特異性：
    Expressed in heart, brain and lung. Present in endothelial cells (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17946

    OMIM: 616759

    KEGG: hsa:51070

    STRING: 9606.ENSP00000375726

    UniGene: Hs.7236



主站蜘蛛池模板： 国产成人无码av一区二区| 久久亚洲色www成人男男| 亚洲欧美中文日韩在线视频一| 夜夜澡人摸人人添人人看| 国产精品女主播在线视频| 老司机午夜福利av无码特黄a| 秋霞午夜成人久久电影网| 精产国品一二三产区蘑菇视频| 亚洲 欧美 日产 综合 在线| 亚洲va综合va国产产va中| 国产午夜精品久久久久免费视| 成人无码av片在线观看| 国产成人免费ā片在线观看老同学 | 久久精品午夜福利| 国产精品无码av天天爽播放器| 中文字幕亚洲精品乱码| 韩国国内大量揄拍精品视频| 精品国产污污免费网站入口| 风流老熟女一区二区三区| 亚洲国产高清av网站| 欧美极品色午夜在线视频| 少妇仑乱a毛片| 色偷偷av男人的天堂| 久久午夜私人影院| 男人边吃奶边做好爽免费视频| 一本一本久久aa综合精品| 正在播放东北夫妻内射| 亚洲一线产区二线产区分布 | 日日夜夜撸啊撸| 一本本月无码-| 亚洲精品色播一区二区| 欧美潮喷少妇100| 国产精品久久久久久久久久久久午夜片 | 免费无码又爽又刺激软件下载直播| 风韵丰满熟妇啪啪区老老熟妇 | 亚洲成a人片在线观看你懂的| 色综合久久久久久久久久| 国产精品自产拍在线18禁| 人妻无码熟妇乱又伦精品视频| 337p粉嫩大胆色噜噜噜| 免费观看性行为视频的网站|