在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Ninein-like protein (NINL), partial

Recombinant Human Ninein-like protein (NINL), partial

  • 中文名稱：
    人NINL重組蛋白
  • 貨號(hào)：
    CSB-YP896492HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人NINL重組蛋白
  • 貨號(hào)：
    CSB-EP896492HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人NINL重組蛋白
  • 貨號(hào)：
    CSB-EP896492HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人NINL重組蛋白
  • 貨號(hào)：
    CSB-BP896492HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人NINL重組蛋白
  • 貨號(hào)：
    CSB-MP896492HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    NINL; KIAA0980; NLP; Ninein-like protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Upon UVC radiation, Nlp interacts with XPA and ERCC1, and enhances their association PMID: 26805762
    2. these data support a model where CC2D2A associates with NINL to provide a docking point for cilia-directed cargo vesicles, suggesting a mechanism by which transition zone proteins can control the protein content of the ciliary compartment. PMID: 26485645
    3. Overexpression of ninein and the ninein-like protein NIP induces fragmentation of the Golgi and causes lysosomes to disperse toward the cell periphery. PMID: 16254247
    4. Breast cancer patients with high expression of Nlp were likely resistant to the treatment of paclitaxel. PMID: 22353935
    5. This review summarises our current knowledge of physiological roles of Nlp, with an emphasis on its potentials in tumourigenesis. PMID: 21505454
    6. findings demonstrate that Cdc2/cyclin B1 is a key regulator in maintaining appropriate degradation and subcellular localization of Nlp, providing novel insights into understanding on the role of Cdc2/cyclin B1 in mitotic progression PMID: 20890132
    7. regulation of Nlp by Aurora B is critical for the completion of cytokinesis, providing novel insights into understanding the machinery of cell cycle progression. PMID: 20864540
    8. Nlp abnormalities may contribute to genomic instability and tumorigenesis and might serve as a potential biomarker for clinical diagnosis and as a therapeutic target. PMID: 20093778
    9. results indicate that ninein-like protein expression is cell cycle-dependent and regulated by anaphase-promoting cyclosome complex-mediated protein degradation PMID: 17403670
    10. Overexpression of Nlp in ovarian tumors raises the possibility that Nlp may play a role in ovarian carcinogenesis. PMID: 18538832
    11. Nlp(isoB)interacts with USH2A and lebercilin. PMID: 18826961
    12. BRCA1 interaction of Nlp might be required for the successful mitotic progression, and abnormalities of Nlp lead to genomic instability. PMID: 19509300
    13. Nlp overexpression might contribute to the development of head and neck squamous cell carcinoma PMID: 19724857

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Note=In interphase cells, NINL is transported to the centrosomes by the dynein-dynactin motor complex (PubMed:16254247). During centrosome maturation, PLK1 directly phosphorylates NINL resulting in its release into the cytoplasm (PubMed:16254247).
  • 組織特異性：
    Expressed in KYSE-150 esophageal carcinoma, HeLa cervical carcinoma and U2OS osteosarcoma cells. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase (at protein level). Expressed in fetal heart, skeletal muscle, liver, lun
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29163

    OMIM: 609580

    KEGG: hsa:22981

    STRING: 9606.ENSP00000278886

    UniGene: Hs.631508



主站蜘蛛池模板： 色婷婷我要去我去也| 久久99精品国产麻豆| 内射人妻视频国内| 国产精品特黄aaaa片在线观看| 国产在线98福利播放视频| 强行糟蹋人妻hd中文| 日本老妇人乱xxy| 伊人无码精品久久一区二区| 亚洲欧美午夜理论电影在线观看 | 青青青国产在线观看资源| 欧美亚洲日本国产其他| 久久精品国产69国产精品亚洲| 欧美一区内射最近更新| 无码h肉动漫在线观看免费| 无码免费中文字幕视频| 精品国产av一二三四区| 国产av国片偷人妻麻豆| 亚洲乱色伦图片区小说| 国产精品18禁污污网站| 亚洲第一aaaaa片| 亚洲最大的imax影院| 天天摸天天做天天添欧美| 三级国产三级在线| 一本本月无码-| 137裸交肉体摄影| 欧美日产成人高清视频| 亚洲乱妇老熟女爽到高潮的片| 日韩乱码人妻无码系列中文字幕| 亚洲精品国产美女久久久| 国产欧美日韩中文久久| а天堂8中文最新版在线官网 | 国产又黄又爽胸又大免费视频| 人妻 日韩 欧美 综合 制服| 中文字幕日韩精品亚洲一区| 免费不卡无码av在线观看| 色偷偷色噜噜狠狠网站久久 | 97影院在线午夜| 国产内射在线激情一区| 日日鲁鲁鲁夜夜爽爽狠狠视频97| 老子午夜精品无码| 玩弄丰满奶水的女邻居|