在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Neutrophil defensin 3 (DEFA3)

  • 中文名稱:
    Recombinant Human Neutrophil defensin 3(DEFA3)
  • 貨號:
    CSB-YP006655HU
  • 規(guī)格:
    ¥2616
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    DEFA3
  • Uniprot No.:
  • 別名:
    DEFA3; DEF3Neutrophil defensin 3; Defensin; alpha 3; HNP-3; HP-3; HP3) [Cleaved into: HP 3-56; Neutrophil defensin 2; HNP-2; HP-2; HP2)]
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Yeast
  • 分子量:
    8.4 kDa
  • 表達區(qū)域:
    39-94aa
  • 氨基酸序列
    DIPEVVVSLAWDESLAPKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
  • 基因功能參考文獻:
    1. High HNP3 expression is associated with IgA Nephropathy. PMID: 27563166
    2. Elevated DEFA3 levels in diabetes are independent of DEFA3 copy numbers. PMID: 25083086
    3. DEFA3 encodes an antibacterial peptide that is bacteriocidal against S. aureus, E. coli, and P. aeruginosa. PMID: 2997278
    4. alpha-Defensin (DEFA3)was the third most differentially overexpressed gene and may be related to the onset of Bell's palsy and Ramsay Hunt Syndrome. PMID: 22737966
    5. The total amount of gingival crevicular fluid human neutrophil peptide 3 were not different among periodontitis, gingivitis, and health control groups; there was no correlation with clinical periodontal parameters. PMID: 20151808
    6. BPI and HNP 1-3 are accumulated in the synovial cavity of patients with rheumatoid arthritis PMID: 12913926
    7. Aerobic bacteria were 100% susceptible to HBD-2 and HBD-3, whereas only 21.4 and 50% of the anaerobes were susceptible to HBD-2 and HBD-3. PMID: 15004048
    8. HNP-3 is a potentially important regulator of neovascularizaiton, suggesting a new link between inflammation and angiogenesis. PMID: 15208269
    9. We have tested the DEFA3 absence in 697 samples from different human populations. The proportion of subjects lacking DEFA3 varies from 10% to 37%, depending on the population tested, suggesting differences in innate immune function between populations. PMID: 17214878
    10. Clostridium difficile toxin B interacts with high affinity with HNP-3 which may provide a defense mechanism against clostridial glucosylating cytotoxins. PMID: 18435932
    11. Upregulation of HNP3 is associated with colorectal adenomas and carcinomas. PMID: 18957723
    12. Salivary HNP-3concentrations increased following exercise PMID: 19263072
    13. DEFA3 was upregulated in IPF patients with acute exacerbation PMID: 19363140
    14. Studies indicate alpha-defensin, the products of neutrophils wase upregulated at the mRNA and protein levels in SLE patients. PMID: 19758174
    15. Plasma levels of alpha-defensins 1-3 are an indicator of neutrophil activation in pregnant and post-partum women. PMID: 17845323

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Alpha-defensin family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 2762

    OMIM: 604522

    KEGG: hsa:1668

    STRING: 9606.ENSP00000328359

    UniGene: Hs.654448



主站蜘蛛池模板: 美女裸免费观看网站| 国产精品怡红院在线观看| 国产voyeur精品偷窥222| 欧美成人精品午夜免费影视| 久久久久蜜桃精品成人片公司| 天堂а√在线最新版中文在线| 日日碰狠狠躁久久躁96avv| 久久无码中文字幕无码| 自拍偷在线精品自拍偷99| 国产精品国产午夜免费看福利| 国产 | 欧洲野花视频天堂视频p| 久久综合久色欧美综合狠狠| 日韩丰满少妇无吗视频激情内射| 国产白嫩护士在线播放| 肉体裸交137日本大胆摄影| 亚洲精品99久久久久中文字幕| 无码任你躁久久久久久老妇| 满春阁精品a∨在线观看| 亚洲国产精品无码久久秋霞| 99久久99久久精品免费观看 | 2021亚洲国产成a在线| 国产精品久久久久无码av色戒| 中文www新版资源在线| 国产熟妇另类久久久久久| 日本xxxx裸体xxxx视频大全| 亚洲丰满熟女一区二区v| 亚洲精品一区二区三区不卡| 国产亚洲精品久久久久5区| 欧美亚洲色欲色一欲www| 日韩av片无码一区二区不卡电影| 国产亚洲精品久久久网站好莱| 性生交大片免费看l| 久久97久久97精品免视看秋霞| 日本动漫瀑乳h动漫啪啪免费| 粗大的内捧猛烈进出| 欧美性猛交xxxx乱大交极品| 国产精品女同一区二区在线| 在线中文字幕亚洲日韩2020| 18禁裸体女免费观看| 久久精品av麻豆| 成人黄网站高清免费视频 |