在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Neuroligin-2 (NLGN2), partial

  • 中文名稱:
    人NLGN2重組蛋白
  • 貨號:
    CSB-YP839877HU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NLGN2重組蛋白
  • 貨號:
    CSB-EP839877HU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NLGN2重組蛋白
  • 貨號:
    CSB-EP839877HU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NLGN2重組蛋白
  • 貨號:
    CSB-BP839877HU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NLGN2重組蛋白
  • 貨號:
    CSB-MP839877HU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    NLGN2
  • Uniprot No.:
  • 別名:
    NLGN2; KIAA1366; Neuroligin-2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Promotes clustering of postsynaptic LHFPL4. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing. Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion.
  • 基因功能參考文獻:
    1. nucleus accumbens neuroligin-2 has a role in depression and stress susceptibility PMID: 29339486
    2. This is the first report of an NLGN2 nonsense variant in humans, adding to the accumulating evidence that links synaptic proteins with a spectrum of neurodevelopmental phenotypes. PMID: 27865048
    3. MDGAs regulate the formation of neuroligin-neurexin trans-synaptic bridges by sterically blocking access of neurexins to neuroligins. PMID: 28641112
    4. Neuroligin-2 was down-regulated in aganglionic colonic segments from Hirschsprung's disease patients. PMID: 24842555
    5. Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic beta cell function PMID: 22528485
    6. Data identified the R215H mutant as a loss-of-function mutant in inducing GABAergic synaptogenesis. Data also suggests that defects in GABAergic synapse formation in the brain may be an important contributing factor for the onset of schizophrenia. PMID: 21551456

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, presynaptic cell membrane.
  • 蛋白家族:
    Type-B carboxylesterase/lipase family
  • 組織特異性:
    Expressed in the blood vessel walls. Detected in colon, brain and pancreas islets of Langerhans (at protein level). Detected in brain, and at lower levels in pancreas islet beta cells.
  • 數據庫鏈接:

    HGNC: 14290

    OMIM: 606479

    KEGG: hsa:57555

    STRING: 9606.ENSP00000305288

    UniGene: Hs.26229



主站蜘蛛池模板: 国产精品无码av片在线观看播| 国产日韩在线时看高清视频| 免费观看全黄做爰的视频| 日本边添边摸边做边爱喷水| 国产成人亚洲综合精品| 国产永久免费观看的黄网站| 蜜臀av 国内精品久久久| 亚洲蜜桃v妇女| 成人免费无码av| 国产青草视频在线观看| 成年美女黄的视频网站| 真人啪啪高潮喷水呻吟无遮挡| 精品无码av一区二区三区不卡 | 在线天堂资源www中文| 水蜜桃亚洲一二三四在线| 国产成人无码18禁午夜福利p| 欧洲美熟女乱又伦av影片| 国产成人午夜福利在线小电影| 亚洲男人的天堂一区二区| 天堂资源最新在线| 18禁裸体女免费观看| 2021国产精品一卡2卡三卡4卡| 色欲天天天综合网| 国产成人小说视频在线观看| 污污污www精品国产网站| 国产成人vr精品a视频| 午夜亚洲乱码伦小说区69堂| 骚虎成人免费99xx| 精品国偷自产在线视频| 99久久人妻精品免费二区| 国产激情无码视频在线播放| 亚洲国产老鸭窝一区二区三区| 人人爽人人爽人人片av亚洲 | 午夜福利国产成人无码gif动图| 亚洲国产激情一区二区三区| 久久性色av亚洲电影| 久久久日韩精品一区二区 | 黄网站成人片免费视频| 国产产在线精品亚洲aavv| 欧美精品黑人粗大视频| 女邻居的大乳中文字幕|