在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human NACHT, LRR and PYD domains-containing protein 5 (NLRP5), partial

  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-YP015873HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-EP015873HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-EP015873HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-BP015873HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-MP015873HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CLR19.8; MATER; Mater protein homolog; Maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; NALP5_HUMAN; NLR family, pyrin domain containing 5; NLRP5; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5; PAN11; PYPAF8
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics. Required for the formation of F-actin cytoplasmic lattices (CPL) in oocytes, which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning. Required for the localization of cortical granules to the cortex of oocytes, via association with the cortical actin scaffold. Required for cortical actin clearance prior to oocyte exocytosis. Involved in regulating post-fertilization Ca(2+) release and endoplasmic reticulum (ER) storage via regulation of ER localization. May be involved in the localization of mitochondria to the cytoplasm and perinuclear region in oocytes and early stage embryos, independent of its role in CPL formation.
  • 基因功能參考文獻:
    1. PSMG4 and NLRP5 appear of particular interest as they were found to be associated with more than one clinical phenotype and are implicated in biological processes considered relevant to the pathophysiology of MS. Also, PSMG4 p.W99R and NLRP5 p.R761L were found to correlate with an earlier age of MS clinical onset. Our data suggests PSMG4 and NLPR5 as potential targets for the development of modifying therapies for MS. PMID: 28501589
    2. expression of MATER and NOX4 proteins are closely related to the follicular development and ovulation with particular regard for ovarian aging PMID: 27515505
    3. NLRP5 mutation is associated with multilocus imprinting disorders and reproductive wastage. PMID: 26323243
    4. characterization of the MATER gene and its protein; this provides a basis for investigating their clinical implications in autoimmune premature ovarian failure and infertility in women PMID: 11925379
    5. NALP5 appears to be a tissue-specific autoantigen involved in hypoparathyroidism in patients with APS-1. Autoantibodies against NALP5 appear to be highly specific and may be diagnostic for this prominent component of APS-1 PMID: 18322283
    6. The nuclear, nucleolar and mitochondrial localization hints at a possible role in RNA processing and the metabolic activity of the cell. PMID: 19192343
    7. MATER protein interacts with tPKCepsilon in cumulus cells under physiological conditions. PMID: 19542546

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, Cortical granule. Mitochondrion. Nucleus, nucleolus. Cytoplasm. Golgi apparatus.
  • 蛋白家族:
    NLRP family
  • 組織特異性:
    Expressed in cumulus cells (at protein level). Highly abundant in oocytes and early embryos, however poorly expressed in somatic tissues such as the liver and spinal cord.
  • 數據庫鏈接:

    HGNC: 21269

    OMIM: 609658

    KEGG: hsa:126206

    STRING: 9606.ENSP00000375063

    UniGene: Hs.356872



主站蜘蛛池模板: 精品久久久久久久中文字幕| 亚洲热无码av一区二区东京热av| 高潮毛片无遮挡高清免费视频| 羞羞影院午夜男女爽爽| 免费无遮挡无码永久视频| 色欲人妻aaaaaaa无码| 影音先锋人妻av中文字幕久久 | 免费国产在线一区二区| 护士av无码在线观看| 免费网站观看www在线观看| 日产一区日产2区| 国产综合精品久久丫| 女人摸下面自熨视频在线播放| 国产精品视频一区国模私拍| 亚洲熟妇无码av不卡在线观看| 无码午夜成人1000部免费视频| 成人国产精品无码网站| 久99视频精品免费观看福利| 国产av天堂亚洲国产av麻豆| 国产免费永久精品无码| 成人性生交大片免费看小说| 成人无码视频97免费| 日本免费高清线视频免费| 精品人妻av一区二区三区| 亚洲国产精品不卡av在线| 国内偷窥一区二区三区视频| 成人免费无码大片a毛片小说| 天美麻花果冻视频大全英文版 | 国产成人av无码精品天堂| 亚洲色成人四虎在线观看| 欧美熟妇性xxxx欧美熟人多毛| 波多野结衣在线精品视频| 国产精品人成视频国模| 伊人精品无码av一区二区三区| 青青草大香焦在线综合视频| 色综合av综合无码综合网站| 亚洲人成网站18禁止大| 色噜噜狠狠色综合av| 免费观看羞羞视频网站| 亚洲欧美成人a∨观看| 国产人妻精品一区二区三首|