在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human NACHT, LRR and PYD domains-containing protein 5 (NLRP5), partial

  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-YP015873HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-EP015873HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-EP015873HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-BP015873HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NLRP5重組蛋白
  • 貨號:
    CSB-MP015873HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CLR19.8; MATER; Mater protein homolog; Maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; NALP5_HUMAN; NLR family, pyrin domain containing 5; NLRP5; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5; PAN11; PYPAF8
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics. Required for the formation of F-actin cytoplasmic lattices (CPL) in oocytes, which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning. Required for the localization of cortical granules to the cortex of oocytes, via association with the cortical actin scaffold. Required for cortical actin clearance prior to oocyte exocytosis. Involved in regulating post-fertilization Ca(2+) release and endoplasmic reticulum (ER) storage via regulation of ER localization. May be involved in the localization of mitochondria to the cytoplasm and perinuclear region in oocytes and early stage embryos, independent of its role in CPL formation.
  • 基因功能參考文獻:
    1. PSMG4 and NLRP5 appear of particular interest as they were found to be associated with more than one clinical phenotype and are implicated in biological processes considered relevant to the pathophysiology of MS. Also, PSMG4 p.W99R and NLRP5 p.R761L were found to correlate with an earlier age of MS clinical onset. Our data suggests PSMG4 and NLPR5 as potential targets for the development of modifying therapies for MS. PMID: 28501589
    2. expression of MATER and NOX4 proteins are closely related to the follicular development and ovulation with particular regard for ovarian aging PMID: 27515505
    3. NLRP5 mutation is associated with multilocus imprinting disorders and reproductive wastage. PMID: 26323243
    4. characterization of the MATER gene and its protein; this provides a basis for investigating their clinical implications in autoimmune premature ovarian failure and infertility in women PMID: 11925379
    5. NALP5 appears to be a tissue-specific autoantigen involved in hypoparathyroidism in patients with APS-1. Autoantibodies against NALP5 appear to be highly specific and may be diagnostic for this prominent component of APS-1 PMID: 18322283
    6. The nuclear, nucleolar and mitochondrial localization hints at a possible role in RNA processing and the metabolic activity of the cell. PMID: 19192343
    7. MATER protein interacts with tPKCepsilon in cumulus cells under physiological conditions. PMID: 19542546

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, Cortical granule. Mitochondrion. Nucleus, nucleolus. Cytoplasm. Golgi apparatus.
  • 蛋白家族:
    NLRP family
  • 組織特異性:
    Expressed in cumulus cells (at protein level). Highly abundant in oocytes and early embryos, however poorly expressed in somatic tissues such as the liver and spinal cord.
  • 數據庫鏈接:

    HGNC: 21269

    OMIM: 609658

    KEGG: hsa:126206

    STRING: 9606.ENSP00000375063

    UniGene: Hs.356872



主站蜘蛛池模板: 亚洲精品久久久久中文第一幕| 精品无码专区毛片| 粗大猛烈进出高潮视频免费看| 色欲精品国产一区二区三区av| 狼友av永久网站免费观看孕交| 亚洲国产日韩欧美综合a| 久久综合狠狠综合久久综合88| 亚洲色欲久久久久综合网| 先锋人妻无码av电影| 久久综合给久久狠狠97色| 真人二十三式性视频(动) | 99er热精品视频| 久久成人麻豆午夜电影| 白丝美女被狂躁免费视频网站| 天天爽天天狠久久久综合麻豆| 丰满大肥婆肥奶大屁股| 亚洲欧美日韩精品久久亚洲区| 国产免费啪嗒啪嗒视频看看 | 在线观看无码不卡av中文| 免费人成激情视频在线观看| 插一插射一射视频| 特级无码毛片免费视频| 久久久欧美精品激情| 久久久肥妇熟女ⅹxxx毛片| 欧美极品少妇×xxxbbb| 国产成人无码免费视频在线| 国产精品丝袜亚洲熟女| 国产精品免费看久久久无码| 免费无码毛片一区二三区| 日本www一道久久久免费| 人人超碰人人超级碰国| 欧美丰满熟妇bbbbbb| 伊人情人色综合网站| 一本无码中文字幕在线观| 国产日产久久高清欧美一区| 久久高清内射无套| 国产成人亚洲综合网站小说 | 用舌头去添高潮无码视频| 狠狠五月深爱婷婷网| 另类亚洲小说图片综合区| 色妞ww精品视频7777|