在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Myotubularin-related protein 9 (MTMR9)

  • 中文名稱:
    人MTMR9重組蛋白
  • 貨號:
    CSB-YP847211HU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人MTMR9重組蛋白
  • 貨號:
    CSB-EP847211HU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人MTMR9重組蛋白
  • 貨號:
    CSB-EP847211HU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MTMR9重組蛋白
  • 貨號:
    CSB-BP847211HU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MTMR9重組蛋白
  • 貨號:
    CSB-MP847211HU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MTMR9
  • Uniprot No.:
  • 別名:
    MTMR9; C8orf9; MTMR8; Myotubularin-related protein 9; Inactive phosphatidylinositol 3-phosphatase 9
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-549
  • 氨基酸序列
    MEFAELIKTP RVDNVVLHRP FYPAVEGTLC LTGHHLILSS RQDNTEELWL LHSNIDAIDK RFVGSLGTII IKCKDFRIIQ LDIPGMEECL NIASSIEALS TLDSITLMYP FFYRPMFEVI EDGWHSFLPE QEFELYSSAT SEWRLSYVNK EFAVCPSYPP IVTVPKSIDD EALRKVATFR HGGRFPVLSY YHKKNGMVIM RSGQPLTGTN GRRCKEDEKL INATLRAGKR GYIIDTRSLN VAQQTRAKGG GFEQEAHYPQ WRRIHKSIER YHILQESLIK LVEACNDQTH NMDRWLSKLE ASNWLTHIKE ILTTACLAAQ CIDREGASIL IHGTEGTDST LQVTSLAQII LEPRSRTIRG FEALIEREWL QAGHPFQQRC AQSAYCNTKQ KWEAPVFLLF LDCVWQILRQ FPCSFEFNEN FLIMLFEHAY ASQFGTFLGN NESERCKLKL QQKTMSLWSW VNQPSELSKF TNPLFEANNL VIWPSVAPQS LPLWEGIFLR WNRSSKYLDE AYEEMVNIIE YNKELQAKVN ILRRQLAELE TEDGMQESP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as an adapter for myotubularin-related phosphatases. Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate and MTMR6 binding affinity for phosphorylated phosphatidylinositols. Positively regulates lipid phosphatase MTMR7 catalytic activity. Increases MTMR8 catalytic activity towards phosphatidylinositol 3-phosphate. The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels. Stabilizes MTMR8 protein levels. Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles. Negatively regulates autophagy, in part via its association with MTMR8. Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6. Does not bind mono-, di- and tri-phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine.
  • 基因功能參考文獻:
    1. Polymorphism of rs2293855 in MTMR9 is associated with measures of glucose tolerance, indices of insulin secretion and indices of insulin sensitivity. PMID: 24937802
    2. MTMR6, which dephosphorylates PI(3)P to PI, and its binding partner MTMR9, are required for macropinocytosis. PMID: 24591580
    3. Our data suggest that genetic variations in the FTO, SCG3 and MTMR9 genes independently influence the risk of metabolic syndrome. PMID: 21796137
    4. Association of single-nucleotide polymorphisms in MTMR9 gene with obesity. PMID: 17855449
    5. MTMR9 greatly enhances the functions of MTMR6 PMID: 19038970

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Endoplasmic reticulum.
  • 蛋白家族:
    Protein-tyrosine phosphatase family, Non-receptor class myotubularin subfamily
  • 組織特異性:
    Expressed in many tissues.
  • 數據庫鏈接:

    HGNC: 14596

    OMIM: 606260

    KEGG: hsa:66036

    STRING: 9606.ENSP00000221086

    UniGene: Hs.591395



主站蜘蛛池模板: 国产欧美丝袜在线二区| 国产午夜精品久久精品电影| 综合久久久久6亚洲综合| 蜜桃视频在线观看免费网址入口| 久久久精品人妻无码专区不卡| 久久电影网午夜鲁丝片免费| 国产mv在线天堂mv免费观看| 亚洲成av人片在线观看一区二区三区 | 亚洲中文字幕无码av| 久久午夜私人影院| 亚洲色欲色欲www在线看| www一区二区www免费| 成人免费无遮挡无码黄漫视频| 小小拗女性bbwxxxx国产| 巨大巨粗巨长 黑人长吊| 无码区国产区在线播放| 99re6热精品视频在线观看| 久久天天躁狠狠躁夜夜2020老熟妇 | 国产主播一区二区三区在线观看| 色99久久久久高潮综合影院| 特黄特色大片免费播放| 三上悠亚精品一区二区久久| 激情文学小说区另类小说同性| 青青草原精品99久久精品66| 亚洲一区二区三区香蕉| 国产白嫩护士在线播放| 日韩视频 中文字幕 视频一区| 国模无码大尺度一区二区三区 | 亚洲国产中文在线视频| 成人性生交大片免费看视频app| 国产国语毛片在线看国产| 乱子伦国产对白在线播放| 67194熟妇在线观看线路1 | 久久久无码精品午夜| 2019精品国自产拍在线不卡| 欧美超级乱婬视频播放| 亚洲欧美综合区丁香五月小说| 天堂√最新版中文在线天堂| 好爽好黄的视频| 亚洲精品国产品国语在线观看| 亚洲成av人在线观看天堂无码|