在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Mitochondria-eating protein (SPATA18)

  • 中文名稱:
    人SPATA18重組蛋白
  • 貨號:
    CSB-YP840563HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SPATA18重組蛋白
  • 貨號:
    CSB-EP840563HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SPATA18重組蛋白
  • 貨號:
    CSB-EP840563HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SPATA18重組蛋白
  • 貨號:
    CSB-BP840563HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SPATA18重組蛋白
  • 貨號:
    CSB-MP840563HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SPATA18
  • Uniprot No.:
  • 別名:
    1700067I02Rik; FLJ32906; MGC93900; Mieap; mitochondria eating protein; SPATA18; Spermatogenesis associated 18; spermatogenesis associated 18 homolog (rat); Spermatogenesis associated protein 18; Spermatogenesis-associated protein 18; SPETEX1; SPT18_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-538
  • 氨基酸序列
    MAENLKRLVS NETLRTLQEK LDFWLKEYNT NTCDQNLNHC LELIEQVAKV QGQLFGILTA AAQEGGRNDG VETIKSRLLP WLEASFTAAS LGKSVDSKVP SLQDTFDRER HKDPSPRDRD MQQLDSNLNS TRSQCNQVQD DLVETEKNLE ESKNRSAISL LAAEEEINQL KKQLKSLQAQ EDARHRNTDQ RSSENRRSEP WSLEERKREQ WNSLKQNADQ QDTEAMSDYK KQLRNLKEEI AVLSAEKSAL QGRSSRSRSP SPAPRSRSCS RSRSASPSTA VKVRRPSPNR SKLSNVARKA ALLSRFSDSY SQARLDAQCL LRRCIDKAET VQRIIYIATV EAFHVAKMAF RHFKIHVRKS LTPSYVGSND FENAVLDYVI CHLDLYDSQS SVNDVIRAMN VNPKISFPPV VDFCLLSDFI QEICCIAFAM QALEPPLDIA YGADGEVFND CKYRRSYDSD FTAPLVLYHV WPALMENDCV IMKGEAVTRR GAFWNSVRSV SRCRSRSLSP ICPRSQIGLN TMSRSRSPSP IRCGLPRF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade unhealthy mitochondria by accumulating lysosomes. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix.
  • 基因功能參考文獻:
    1. The physical interaction of Mieap, BNIP3 and NIX at the mitochondrial outer membrane may play a critical role in the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. PMID: 22292033
    2. Mieap induces intramitochondrial lysosome-like organella that plays a critical role in mitochondrial quality control by eliminating oxidized mitochondrial proteins PMID: 21264221
    3. Mieap induced vacuole-like structures (designated as MIV for Mieap-induced vacuole), which engulfed and degraded the unhealthy mitochondria by accumulating lysosomes PMID: 21264228
    4. show that SPATA18 transcription is induced by p53 in a variety of cell types of both human and mouse origin PMID: 21300779
    5. beta-sarcoglycan and SPATA18 may have a role in limb-girdle muscular dystrophy type 2E PMID: 16088906

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Mitochondrion outer membrane.
  • 蛋白家族:
    MIEAP family
  • 數據庫鏈接:

    HGNC: 29579

    OMIM: 612814

    KEGG: hsa:132671

    STRING: 9606.ENSP00000295213

    UniGene: Hs.527090



主站蜘蛛池模板: 精品久久人妻av中文字幕| 男人和女人高潮做爰视频| 成 人 网 站不卡在线观看| 大又大又粗又硬又爽少妇毛片 | 亚洲人成电影网站色| 日本高清在线天码一区播放| 亚洲欧美日韩中文在线制服| 麻豆高清免费国产一区| 亚洲国产成人综合一区二区三区| 台湾无码av一区二区三区| 欧美综合在线激情专区| 5566先锋影音夜色资源站在线观看| 在线看片免费人成视频福利 | 99久热re在线精品99re8热视频 | 日本免费人成在线观看网站| 国产内射老熟女aaaa| 豆国产96在线 | 亚洲| 亚洲伊人成综合人影院青青青| 麻豆成人av不卡一二三区| 加勒比无码一区二区三区| 日韩精品无码视频一区二区蜜桃| 国产在线拍揄自揄视频网试看| 无码日韩精品一区二区三区免费| 白天躁晚上躁麻豆视频| 中文字幕av伊人av无码av| 丁香五月激情综合亚洲| 少妇人妻丰满做爰xxx| 97午夜理论片在线影院| 国产粉嫩小泬在线观看泬| 久久久精品94久久精品| 色综合久久无码五十路人妻| 国产熟女亚洲精品麻豆| 日韩无套内射高潮| 真人二十三式性视频(动)| 国产精品无码一区二区三区| 亚洲性色成人av| 国产精品无码久久久久久| 久久久久久毛片免费播放| 久久精品成人欧美大片| 精品一区二区三区四区五区六区| 少妇厨房愉情理9仑片视频|