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  4. Recombinant Human Methionine aminopeptidase 1D, mitochondrial (METAP1D)

Recombinant Human Methionine aminopeptidase 1D, mitochondrial (METAP1D)

  • 中文名稱：
    人METAP1D重組蛋白
  • 貨號：
    CSB-YP747607HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人METAP1D重組蛋白
  • 貨號：
    CSB-EP747607HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人METAP1D重組蛋白
  • 貨號：
    CSB-EP747607HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人METAP1D重組蛋白
  • 貨號：
    CSB-BP747607HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人METAP1D重組蛋白
  • 貨號：
    CSB-MP747607HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    METAP1D
  • Uniprot No.：
  • 別名：
    METAP1D; MAP1DMethionine aminopeptidase 1D; mitochondrial; MAP 1D; MetAP 1D; EC 3.4.11.18; Methionyl aminopeptidase type 1D; mitochondrial; Peptidase M 1D
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    20-335
  • 氨基酸序列
    S SPLNHIYLHK QSSSQQRRNF FFRRQRDISH SIVLPAAVSS AHPVPKHIKK PDYVTTGIVP DWGDSIEVKN EDQIQGLHQA CQLARHVLLL AGKSLKVDMT TEEIDALVHR EIISHNAYPS PLGYGGFPKS VCTSVNNVLC HGIPDSRPLQ DGDIINIDVT VYYNGYHGDT SETFLVGNVD ECGKKLVEVA RRCRDEAIAA CRAGAPFSVI GNTISHITHQ NGFQVCPHFV GHGIGSYFHG HPEIWHHAND SDLPMEEGMA FTIEPIITEG SPEFKVLEDA WTVVSLDNQR SAQFEHTVLI TSRGAQILTK LPHEA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. May play a role in colon tumorigenesis.
  • 基因功能參考文獻：
    1. Observational study of gene-disease association. (HuGE Navigator) PMID: 20877624
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    3. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
    4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    5. MAP1D is a potentially oncogenic, novel member of the MAP gene family that may play an important role in colon tumorigenesis PMID: 16568094

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  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Peptidase M24A family, Methionine aminopeptidase type 1 subfamily
  • 組織特異性：
    Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level).
  • 數據庫鏈接：

    HGNC: 32583

    OMIM: 610267

    KEGG: hsa:254042

    STRING: 9606.ENSP00000315152

    UniGene: Hs.298250



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