在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial

Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial

  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-YP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-EP863164HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-BP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-MP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PITPNM3
  • Uniprot No.：
  • 別名：
    CORD5; Membrane associated phosphatidylinositol transfer protein 3; membrane-associated 3; Membrane-associated phosphatidylinositol transfer protein 3; MGC157740; MGC157741; NIR 1; NIR-1; NIR1; Phosphatidylinositol transfer protein; Phosphatidylinositol transfer protein, membrane-associated 3; PITM3_HUMAN; PITPnm 3; PITPNM; PITPNM family member 3; Pitpnm3; PYK2 N terminal domain interacting receptor 1; Pyk2 N-terminal domain-interacting receptor 1; RDGBA3; Retinal degeneration B alpha 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions.
  • 基因功能參考文獻(xiàn)：
    1. CCL18 can increase the invasive ability of non-small cell lung cancer cells by binding to its receptor Nir1. PMID: 26756176
    2. CCL18 enhances hepatocellular carcinoma (HCC) cell migration, invasion, and epithelial-mesenchymal transition (EMT) through the expression of PITPNM3 and the activation of the NF-kappaB signaling pathway. PMID: 26449829
    3. Data indicate that PYK2 N-terminal domain interacting receptor 1 (Nir1) could induce epithelial-mesenchymal transition by stabilising Snail via the PI3K/Akt/GSK3beta/Snail signalling pathway through binding to CCL18. PMID: 24001613
    4. Our observations of the PITPNM3 p.Q626H mutation carriers confirm that CORD5 is a disease not to mix with other retinal degenerations mapped to 17p13. PMID: 22405330
    5. CCL18 derived from Tumor-associated macrophages (TAMs) lays a critical role in promoting breast cancer metastasis via its receptor, PITPNM3. PMID: 21481794
    6. Thus, mutations in PITPNM3 do not appear to be a major cause of cone or cone-rod dystrophy. PMID: 20590364
    7. Our finding on the first mutation in the human homologue of Drosophila rdgB indicates novel pathways and a potential important role of the PITPNM3 in mammalian phototransduction. PMID: 17377520
    8. Mutation in the PYK2-binding domain of PITPNM3 causes autosomal dominant cone dystrophy (CORD5) in two Swedish families. PMID: 18188949

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Cone-rod dystrophy 5 (CORD5)
  • 亞細(xì)胞定位：
    Endomembrane system; Peripheral membrane protein.
  • 蛋白家族：
    PtdIns transfer protein family, PI transfer class IIA subfamily
  • 組織特異性：
    Detected in brain and spleen, and at low levels in ovary.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21043

    OMIM: 600977

    KEGG: hsa:83394

    STRING: 9606.ENSP00000262483

    UniGene: Hs.183983



主站蜘蛛池模板： 香港三日本三级少妇三级66| 国产在线98福利播放视频| 国产肉体xxxx裸体784大胆| 国产内射爽爽大片视频社区在线| 日本乱偷互换人妻中文字幕| 国产成人av片无码免费| 狠日狠干日日射| 婷婷五月综合缴情在线视频| 边啃奶头边躁狠狠躁| 国产在线观看免费观看不卡| 国产av无码专区影视| 波多野结衣中文字幕一区二区三区| 亚洲国产综合精品 在线 一区 | 无码人妻斩一区二区三区| 亚洲综合久久一区二区| 日本真人做爰免费的视频| 任你躁久久精品6| 色在线亚洲视频www| 国产精品爽爽久久久久久蜜臀| 国产妇女馒头高清泬20p多| 97精品一区二区视频在线观看| 天天天天做夜夜夜夜做无码| 人人爽人人爽人人片a免费| 国产精品99久久久久久董美香| 国产69精品久久久久久妇女迅雷| 艳妇乳肉豪妇荡乳| 久久人人爽人人爽人人爽| 日本高清色www网站色噜噜噜| 欧美黑人xxxx性高清版| 国产精品久久久久久久久久久久午夜片 | 日韩成人大屁股内射喷水| 亚洲日韩精品欧美一区二区一| 色欲天天婬色婬香综合网完整| 中文午夜人妻无码看片| 色狠狠成人综合网| 无码区日韩特区永久免费系列| 国内精品自线在拍2020不卡| 色婷婷综合久色aⅴ五区最新| 人人妻人人藻人人爽欧美一区| 性男女做视频观看网站| 被灌满精子的波多野结衣|