在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial

Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial

  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-YP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-EP863164HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-BP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-MP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PITPNM3
  • Uniprot No.：
  • 別名：
    CORD5; Membrane associated phosphatidylinositol transfer protein 3; membrane-associated 3; Membrane-associated phosphatidylinositol transfer protein 3; MGC157740; MGC157741; NIR 1; NIR-1; NIR1; Phosphatidylinositol transfer protein; Phosphatidylinositol transfer protein, membrane-associated 3; PITM3_HUMAN; PITPnm 3; PITPNM; PITPNM family member 3; Pitpnm3; PYK2 N terminal domain interacting receptor 1; Pyk2 N-terminal domain-interacting receptor 1; RDGBA3; Retinal degeneration B alpha 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions.
  • 基因功能參考文獻(xiàn)：
    1. CCL18 can increase the invasive ability of non-small cell lung cancer cells by binding to its receptor Nir1. PMID: 26756176
    2. CCL18 enhances hepatocellular carcinoma (HCC) cell migration, invasion, and epithelial-mesenchymal transition (EMT) through the expression of PITPNM3 and the activation of the NF-kappaB signaling pathway. PMID: 26449829
    3. Data indicate that PYK2 N-terminal domain interacting receptor 1 (Nir1) could induce epithelial-mesenchymal transition by stabilising Snail via the PI3K/Akt/GSK3beta/Snail signalling pathway through binding to CCL18. PMID: 24001613
    4. Our observations of the PITPNM3 p.Q626H mutation carriers confirm that CORD5 is a disease not to mix with other retinal degenerations mapped to 17p13. PMID: 22405330
    5. CCL18 derived from Tumor-associated macrophages (TAMs) lays a critical role in promoting breast cancer metastasis via its receptor, PITPNM3. PMID: 21481794
    6. Thus, mutations in PITPNM3 do not appear to be a major cause of cone or cone-rod dystrophy. PMID: 20590364
    7. Our finding on the first mutation in the human homologue of Drosophila rdgB indicates novel pathways and a potential important role of the PITPNM3 in mammalian phototransduction. PMID: 17377520
    8. Mutation in the PYK2-binding domain of PITPNM3 causes autosomal dominant cone dystrophy (CORD5) in two Swedish families. PMID: 18188949

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Cone-rod dystrophy 5 (CORD5)
  • 亞細(xì)胞定位：
    Endomembrane system; Peripheral membrane protein.
  • 蛋白家族：
    PtdIns transfer protein family, PI transfer class IIA subfamily
  • 組織特異性：
    Detected in brain and spleen, and at low levels in ovary.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21043

    OMIM: 600977

    KEGG: hsa:83394

    STRING: 9606.ENSP00000262483

    UniGene: Hs.183983



主站蜘蛛池模板： 手机看片福利一区二区三区| 久久99精品久久久久子伦| 综合 欧美 亚洲日本| 小辣椒福利视频导航| 玩肥熟老妇bbw视频| 国产超级va在线观看视频| 黑人巨大精品欧美| 国产亚洲精品久久久久婷婷瑜伽| 伊人久久大香线蕉亚洲| 无码少妇一区二区浪潮免费| 免费观看男女性高视频| 久久成人国产精品| 色哟哟国产精品免费观看| 国产白丝精品爽爽久久蜜臀| 青青草99久久精品国产综合| 久久久久成人精品| 国产欧美久久一区二区三区| 男男女女爽爽爽免费视频| 亚洲精品久久久久国产剧8| 欧美成人一区二区三区片免费 | 欧美欧洲成本大片免费| 国产精品三级在线观看无码| 亚洲中文字幕无码mv| 亚洲男人的天堂在线va| 亚洲性猛交xxxx| 国产又大又粗又爽的毛片| 人人妻人人爽人人澡av| 中文无码人妻影音先锋| www污污污抽搐喷潮com| 亚洲精品无码久久千人斩| 精品免费国偷自产在线视频| 四虎国产精品永久在线观看| 狠狠五月深爱婷婷网| 无码中文字幕va精品影院| 成人毛片18女人毛片免费| 中文字幕欧美人妻精品一区| 另类国产精品一区二区| 久久麻豆成人精品av| 好湿好紧太硬了我太爽了视频| 美女被张开双腿日出白浆| 高潮迭起av乳颜射后入|