在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial

Recombinant Human Membrane-associated phosphatidylinositol transfer protein 3 (PITPNM3), partial

  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-YP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-EP863164HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-BP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PITPNM3重組蛋白
  • 貨號(hào)：
    CSB-MP863164HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PITPNM3
  • Uniprot No.：
  • 別名：
    CORD5; Membrane associated phosphatidylinositol transfer protein 3; membrane-associated 3; Membrane-associated phosphatidylinositol transfer protein 3; MGC157740; MGC157741; NIR 1; NIR-1; NIR1; Phosphatidylinositol transfer protein; Phosphatidylinositol transfer protein, membrane-associated 3; PITM3_HUMAN; PITPnm 3; PITPNM; PITPNM family member 3; Pitpnm3; PYK2 N terminal domain interacting receptor 1; Pyk2 N-terminal domain-interacting receptor 1; RDGBA3; Retinal degeneration B alpha 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions.
  • 基因功能參考文獻(xiàn)：
    1. CCL18 can increase the invasive ability of non-small cell lung cancer cells by binding to its receptor Nir1. PMID: 26756176
    2. CCL18 enhances hepatocellular carcinoma (HCC) cell migration, invasion, and epithelial-mesenchymal transition (EMT) through the expression of PITPNM3 and the activation of the NF-kappaB signaling pathway. PMID: 26449829
    3. Data indicate that PYK2 N-terminal domain interacting receptor 1 (Nir1) could induce epithelial-mesenchymal transition by stabilising Snail via the PI3K/Akt/GSK3beta/Snail signalling pathway through binding to CCL18. PMID: 24001613
    4. Our observations of the PITPNM3 p.Q626H mutation carriers confirm that CORD5 is a disease not to mix with other retinal degenerations mapped to 17p13. PMID: 22405330
    5. CCL18 derived from Tumor-associated macrophages (TAMs) lays a critical role in promoting breast cancer metastasis via its receptor, PITPNM3. PMID: 21481794
    6. Thus, mutations in PITPNM3 do not appear to be a major cause of cone or cone-rod dystrophy. PMID: 20590364
    7. Our finding on the first mutation in the human homologue of Drosophila rdgB indicates novel pathways and a potential important role of the PITPNM3 in mammalian phototransduction. PMID: 17377520
    8. Mutation in the PYK2-binding domain of PITPNM3 causes autosomal dominant cone dystrophy (CORD5) in two Swedish families. PMID: 18188949

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Cone-rod dystrophy 5 (CORD5)
  • 亞細(xì)胞定位：
    Endomembrane system; Peripheral membrane protein.
  • 蛋白家族：
    PtdIns transfer protein family, PI transfer class IIA subfamily
  • 組織特異性：
    Detected in brain and spleen, and at low levels in ovary.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21043

    OMIM: 600977

    KEGG: hsa:83394

    STRING: 9606.ENSP00000262483

    UniGene: Hs.183983



主站蜘蛛池模板： 伊人久久大香线蕉av五月天宝贝| 中文天堂国产最新| 性人久久网av| 亚洲国产精品18久久久久久 | 精品国产一区二区三区久久狼| 亚洲 欧美 中文 日韩aⅴ| 国产成人精品a视频免费福利| 亚洲国产精品自产在线播放| 欧美一夜爽爽爽爽爽爽| 99精品国产福利在线观看| 最新亚洲伦理中文字幕| 熟妇人妻不卡中文字幕| 精品1卡二卡三卡四卡老狼| 精品久久久久久久免费人妻| 精产国品一二三产区9977| 国产av偷闻女邻居内裤被发现| 好男人社区www在线观看| 狠狠色综合网丁香五月| 香港台湾经典三级a视频| 午夜成人影院网站18进| 无码潮喷a片无码高潮视频| 国产亚洲精品精华液| 国产精品情侣呻吟对白视频| 尤物av无码国产在线看| 中国凸偷窥xxxx自由视频| 内射人妻少妇无码一本一道| 国产乱人伦av在线无码| 宅男666在线永久免费观看| 麻婆豆传媒一区二区三区| 国产亚洲日韩在线a不卡| 中文字幕亚洲综合久久菠萝蜜| 久久精品天天中文字幕人妻| 欧美老妇bbbwwbbbww| 日日摸日日碰夜夜爽无码| 99久久精品视香蕉蕉| 男受被做哭激烈娇喘gv视频| 日本一区二区三区免费视频| 精品av一区二区久久久| 欧美人与物videos另类| 国产亚洲色婷婷久久99精品| 亚洲美女视频高清在线看|