Recombinant Human MOB kinase activator 2 (MOB2)

中文名稱：

人MOB2重組蛋白
貨號：

CSB-YP765110HU
規格：
來源：

Yeast
其他：

中文名稱：

人MOB2重組蛋白
貨號：

CSB-EP765110HU
規格：
來源：

E.coli
其他：

中文名稱：

人MOB2重組蛋白
貨號：

CSB-EP765110HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MOB2重組蛋白
貨號：

CSB-BP765110HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人MOB2重組蛋白
貨號：

CSB-MP765110HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MOB2
Uniprot No.：

Q70IA6
別名：

HCCA2; HCCA2 gene; HCCA2 protein; MOB kinase activator 2; MOB2; Mob2 homolog; MOB2 Mps One Binder homolog; MOB2_HUMAN; Mps one binder kinase activator like 2; Mps one binder kinase activator-like 2
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-237
氨基酸序列

MDWLMGKSKA KPNGKKPAAE ERKAYLEPEH TKARITDFQF KELVVLPREI DLNEWLASNT TTFFHHINLQ YSTISEFCTG ETCQTMAVCN TQYYWYDERG KKVKCTAPQY VDFVMSSVQK LVTDEDVFPT KYGREFPSSF ESLVRKICRH LFHVLAHIYW AHFKETLALE LHGHLNTLYV HFILFAREFN LLDPKETAIM DDLTEVLCSG AGGVHSGGSG DGAGSGGPGA QNHVKER
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.
基因功能參考文獻：
1. The altered cell-matrix adhesion and cell motility induced by hMOB2 expression was caused by the assembly of focal adhesions. PMID: 25779224
2. hMOB2 interacts with RAD50, facilitating the recruitment of the MRE11-RAD50-NBS1 (MRN) DNA damage sensor complex and activated ATM to DNA damaged chromatin. PMID: 25460043
3. MOB2 overexpression induces apoptosis and inhibits the growth of human hepatic cancer cells PMID: 23326134
4. Data indicate that human MOB2 is a negative regulator of human NDR kinases in biochemical and biological settings. PMID: 20624913
5. Binds to and stimulates the kinase activity of the related human serine-threonine kinases NDR1 and NDR2. PMID: 15067004
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亞細胞定位：

Nucleus. Cytoplasm, perinuclear region.
蛋白家族：

MOB1/phocein family
數據庫鏈接：

HGNC: 24904

OMIM: 611969

KEGG: hsa:81532

STRING: 9606.ENSP00000328694

UniGene: Hs.370360