在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human MICOS complex subunit MIC19 (CHCHD3)

  • 中文名稱:
    Recombinant Human MICOS complex subunit MIC19(CHCHD3)
  • 貨號:
    CSB-YP873679HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human MICOS complex subunit MIC19(CHCHD3)
  • 貨號:
    CSB-EP873679HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human MICOS complex subunit MIC19(CHCHD3)
  • 貨號:
    CSB-BP873679HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human MICOS complex subunit MIC19(CHCHD3)
  • 貨號:
    CSB-MP873679HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CHCHD3
  • Uniprot No.:
  • 別名:
    CHCH3_HUMAN; CHCHD 3; Chchd3; Coiled coil helix coiled coil helix domain containing 3; Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial; Coiled-coil-helix-coiled-coil-helix domain-containing protein 3; FLJ20420; MINOS3; mitochondrial; Mitochondrial inner membrane organizing system 3; PPP1R22; Protein phosphatase 1 regulatory subunit 22
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-227
  • 氨基酸序列
    MGGTTSTRRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQKAAEEVEAKFKRYESHPVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHAKQSMLEKGG
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
  • 基因功能參考文獻:
    1. Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50. PMID: 28808085
    2. The findings suggest that Mic19 is a redox-dependent regulator of mitochondrial contact site and crista organizing system complex function. PMID: 26416881
    3. both the myristoylation and the CHCH domain are essential for the import and mitochondrial localization of ChChd3. Once imported, ChChd3 binds to Mia40 for further folding and assembly into macromolecular complexes. PMID: 23019327
    4. ChChd3 is a scaffolding protein that stabilizes protein complexes involved in maintaining crista architecture and protein import and is thus essential for maintaining mitochondrial structure and function. PMID: 21081504
    5. mitofilin helps regulate mitochondrial morphology and at least four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import PMID: 17624330

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion inner membrane; Lipid-anchor; Intermembrane side. Cytoplasm. Nucleus. Mitochondrion.
  • 蛋白家族:
    MICOS complex subunit Mic19 family, Metazoan Mic19 subfamily
  • 組織特異性:
    Detected at low levels in brain, placenta, lung, liver, kidney and pancreas with increased levels in heart and skeletal muscle. Higher expression in primary lung cancers than in normal lung tissue.
  • 數據庫鏈接:

    HGNC: 21906

    OMIM: 613748

    KEGG: hsa:54927

    STRING: 9606.ENSP00000262570

    UniGene: Hs.655010



主站蜘蛛池模板: 成品人视频ww入口| 亚洲色大成网站www久久九九| 韩国日本三级在线观看| 50岁退休熟女露脸高潮| 国产人妻大战黑人第1集| 高潮好爽视频在线观看| 影音先锋男人av鲁色资源网| 婷婷四房综合激情五月| 亚洲另类欧美综合在线| 亚洲成a人片在线观看的电影| 无限看片在线版免费视频大全 | 好男人www社区| 人妻少妇精品视频无码综合| 18禁精品久久久国产精品久久久| 国产良妇出轨视频在线观看| 日本肥老妇色xxxxx日本老妇| 人妻精品制服丝袜久久久| 久9视频这里只有精品试看| 亚洲色成人网站www永久| 国产精品久免费的黄网站| 国产高潮又爽又刺激的视频| 18禁黄久久久aaa片| 人妻去按摩店被黑人按中出| 欧美大片va欧美在线播放| 动漫成人无码精品一区二区三区| 奇米777四色影视在线看| 色依依av在线| 色综合 图片区 小说区| 亚洲va综合va国产产va中| 亚洲精品色午夜无码专区日韩 | 日韩成人无码毛片一区二区| 精品综合久久久久久97| 人妻av中文系列| 丰满少妇作爱视频免费观看| 国产成人亚洲精品无码车a| 国产9 9在线 | 欧洲| 国产老熟女网站| 无码高潮喷吹在线观看 | 无遮无挡三级动态图| 亚洲中文有码字幕日本| 国产精品日本一区二区不卡视频|