在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Krueppel-like factor 17 (KLF17)

  • 中文名稱:
    人KLF17重組蛋白
  • 貨號:
    CSB-YP686385HU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人KLF17重組蛋白
  • 貨號:
    CSB-EP686385HU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人KLF17重組蛋白
  • 貨號:
    CSB-EP686385HU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人KLF17重組蛋白
  • 貨號:
    CSB-BP686385HU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人KLF17重組蛋白
  • 貨號:
    CSB-MP686385HU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    KLF17
  • Uniprot No.:
  • 別名:
    FLJ40160; KLF17; KLF17_HUMAN; Krueppel like factor 17; Krueppel-like factor 17; Novel zinc finger protein; RP4 675G8.1; RP4675G8.1; Zfp393; Zinc finger protein 393; ZNF393
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-389
  • 氨基酸序列
    MYGRPQAEME QEAGELSRWQ AAHQAAQDNE NSAPILNMSS SSGSSGVHTS WNQGLPSIQH FPHSAEMLGS PLVSVEAPGQ NVNEGGPQFS MPLPERGMSY CPQATLTPSR MIYCQRMSPP QQEMTIFSGP QLMPVGEPNI PRVARPFGGN LRMPPNGLPV SASTGIPIMS HTGNPPVPYP GLSTVPSDET LLGPTVPSTE AQAVLPSMAQ MLPPQDAHDL GMPPAESQSL LVLGSQDSLV SQPDSQEGPF LPEQPGPAPQ TVEKNSRPQE GTGRRGSSEA RPYCCNYENC GKAYTKRSHL VSHQRKHTGE RPYSCNWESC SWSFFRSDEL RRHMRVHTRY RPYKCDQCSR EFMRSDHLKQ HQKTHRPGPS DPQANNNNGE QDSPPAAGP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

相關產品

靶點詳情

  • 功能:
    Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
  • 基因功能參考文獻:
    1. Low Expressions of KLF17 is associated with lung adenocarcinoma. PMID: 28454121
    2. Suggest that KLF17 inhibits esophageal carcinoma development and may serve as a potential therapeutic target. PMID: 26617836
    3. Enhanced KLF17 expression sensitizes ERalpha-positive breast cancer cells to endocrine therapy.KLF17-ERalpha interaction plays a potential role in inhibition of ERalpha-dependent breast cancer progression. PMID: 27107895
    4. KLF17 empowers TGF-beta/Smad signaling by targeting Smad3-dependent pathway to suppress tumor growth and metastasis during cancer progression. PMID: 25766320
    5. Tumor-suppressive p53 signaling is critical for KLF17 to inhibit cancer metastasis in Non-small Cell Lung Cancer. PMID: 25911104
    6. A small subset of Myoepithelial tumors harbor FUS rearrangements, two thirds of them being associated with KLF17 fusion. PMID: 25706482
    7. In this review, we focus on the functions, roles, and regulatory networks of these five KLFs in HCC, summarize key pathways, and propose areas for further investigation PMID: 25652467
    8. The reduced expression of KLF17 promoted the motility and proliferation ability of TPC1 cells by altering the expression of tight junction protein 1 and Snai1, and activating the AKT pathway by upregulating inhibitor of DNA binding 1. PMID: 25109837
    9. mutant p53 enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells PMID: 25111898
    10. The reduced expression of KLF17 protein in gastric cancer was correlated with tumor size, pN stage and lymphovascular invasion and was an independent predictor for poor survival in patients undergoing surgery for gastric cancer. PMID: 24947617
    11. KLF17 might be one of the downstream signalling molecules of DJ-1. PMID: 24504364
    12. KLF17 may have an oncogenic role during EEC progression via initiating EMT through the regulation of TWIST1 PMID: 24220291
    13. Overall, these findings suggest a repressing role of KLF17 in tumor invasion PMID: 23325444
    14. it is possible that KLF17 inhibits tumor growth in lung adenocarcinoma. PMID: 22240024
    15. KLF17 has a role in transcriptional regulation of metastasis by Id1 [review] PMID: 19951400
    16. KLF17 is a new member of the Sp/KLF family of transcription factors. PMID: 16460907
    17. demonstrate that KLF17 expression is significantly downregulated in primary human breast cancer samples and that the combined expression pattern of KLF17 and Id1 can serve as a potential biomarker for lymph node metastasis in breast cancer PMID: 19801974

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Sp1 C2H2-type zinc-finger protein family
  • 數據庫鏈接:

    HGNC: 18830

    OMIM: 609602

    KEGG: hsa:128209

    STRING: 9606.ENSP00000361373

    UniGene: Hs.567674



主站蜘蛛池模板: 天天做天天爱天天综合网2021| 2021久久精品国产99国产精品| 亚洲国产成人极品综合| 久久精品成人免费观看三| 日产欧美国产日韩精品| 久久99精品久久久久久蜜芽 | 亚洲 欧美 日韩 国产综合 在线| 动漫精品啪啪一区二区三区| 国产av国片偷人妻麻豆| 亚洲国产最大av| 中文字幕无码专区人妻系列| 国内精品2020情侣视频| 久久久久无码精品国产| 国产老熟女伦老熟妇露脸| 大学生高潮无套内谢视频| 精品无码日韩一区二区三区不卡| 国产尤物人成免费观看| 好想被狂躁无码视频在线观看| 国自产偷精品不卡在线| 亚洲日韩乱码一区二区三区四区| 色欲精品国产一区二区三区av| 成人无码嫩草影院| 国产精品久久国产精麻豆99网站| 少妇一晚三次一区二区三区| 无码中文字幕日韩专区视频| 亚洲精品电影院| 国产爆乳无码av在线播放| 无码日日模日日碰夜夜爽| 早起邻居人妻奶罩太松av| 免费大片黄在线观看| 人人妻人人妻人人片av| 午夜无码性爽快影院6080| 日本xxxx18野外无毒不卡| 国产亚洲精品精品国产亚洲综合| 欧美日本国产va高清cabal | 大学生久久香蕉国产线看观看| 国产超碰人人做人人爱一二区视品| 欧美亚洲日本高清不卡| 国产人妻精品久久久久野外| 国产色诱视频在线观看| 国产婷婷丁香五月缴情成人网|