在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Kinesin-like protein KIF13B (KIF13B), partial

  • 中文名稱:
    人KIF13B重組蛋白
  • 貨號:
    CSB-YP873625HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人KIF13B重組蛋白
  • 貨號:
    CSB-EP873625HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人KIF13B重組蛋白
  • 貨號:
    CSB-EP873625HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人KIF13B重組蛋白
  • 貨號:
    CSB-BP873625HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人KIF13B重組蛋白
  • 貨號:
    CSB-MP873625HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    GAKIN; Guanylate kinase associated kinesin; KI13B_HUMAN; KIAA0639; KIF 13B; KIF13B; Kinesin 13B; Kinesin family member 13B; Kinesin like protein GAKIN; Kinesin like protein KIF13B; Kinesin-like protein GAKIN; Kinesin-like protein KIF13B; OTTHUMP00000225649
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes.
  • 基因功能參考文獻:
    1. Study provides evidence that KIF13B and NPHP4 are both required for establishment of a specialized caveolin-1 membrane microdomain at the ciliary transition zone, which is essential for Shh-induced accumulation of SMO in the primary cilium as well as for activation of GLI-mediated target gene expression. PMID: 28134340
    2. Findings show that the high-affinity binding of KIF13B to DLG guanylate kinase (GK) domain does not require phosphorylation of KIF13B and that DLG binds to an unphosphorylated and autonomously folded domain within its stalk region (MAGUK binding stalk [MBS] domain) with high specificity and affinity. PMID: 27642159
    3. lnc-KIF13B-1, a long non-coding RNA (rs6434720) is associated with corticobasal degeneration. PMID: 26077951
    4. KIF13B is an essential molecular motor required for the trafficking of VEGFR2 from the Golgi, and its delivery to the endothelial cell surface mediates angiogenesis. PMID: 25128562
    5. Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. PMID: 21057110
    6. These results reveal that GAKIN/KIF13B is a key intermediate linking Par1b to the regulation of axon formation. PMID: 20194617
    7. These results suggest that, in neurons, the GAKIN-PIP3BP complex transports PIP3 to the neurite ends and regulates neuronal polarity formation. PMID: 16864656
    8. Binding of the SH3-I3-GUK module of hDlg to GAKIN activates the microtubule-stimulated ATPase activity of GAKIN by approximately 10-fold. We propose: the cargo-mediated regulation of motor activity is a general paradigm for the activation of kinesins. PMID: 17696365

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell projection, axon. Note=accumulates at the distal part of the microtubules in the tips of axons, but not of dendrites.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 14405

    OMIM: 607350

    KEGG: hsa:23303

    STRING: 9606.ENSP00000427900

    UniGene: Hs.444767



主站蜘蛛池模板: 国产精品一区二区 尿失禁| 99久热re在线精品视频| 免费无遮挡在线观看网站| 中国女人内谢69xxxx免费视频| 人妻丰满被色诱中文字幕| 精品国产综合成人亚洲区| 东京热无码一区二区三区av| 中文字幕有码无码av| 三级4级全黄60分钟| 国产yw8825免费观看网站| 少妇人妻陈艳和黑人教练| 黄瓜视频在线观看网址| 全部免费毛片在线播放| 亚洲乱码日产精品bd在线看| 最近中文字幕mv在线视频看| 中文无码久久精品| 人人妻人人做人人爽| 尹人香蕉久久99天天拍欧美p7| 精品免费看国产一区二区| 亚洲区日韩精品中文字幕| 国产精品不卡无码av在线播放| 狠狠色老熟妇老熟女| 久久久国产精品人人片| 国产乱人伦在线播放| 蕾丝av无码专区在线观看| 日本亚洲欧美综合在线| 无码精品人妻一区二区三区影院 | 国产做爰又粗又大又爽动漫| 男人狂躁进女人下面免费视频| 成人国产亚洲精品a区天堂| 99re6热在线精品视频观看| 337p日本大胆欧美裸体艺术| 久久久久免费看黄a片app| 精品人伦一区二区三区潘金莲| 麻豆丰满少妇chinese| 两性色午夜视频免费无码| 天堂中文最新版在线官网在线| 后进式无遮挡啪啪摇乳动态图 | 真实人与人性恔配视频| 欧美日韩亚洲国产欧美电影| 日韩精品一区二区三区免费视频 |