在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Isthmin-1 (ISM1)

In Stock
  • 中文名稱(chēng):
    人ISM1重組蛋白
  • 貨號(hào):
    CSB-EP011850HU
  • 規(guī)格:
    ¥1536
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    ISM1
  • Uniprot No.:
  • 別名:
    ISM1; C20orf82; ISM; Isthmin-1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 來(lái)源:
    E.coli
  • 分子量:
    69.1 kDa
  • 表達(dá)區(qū)域:
    30-464aa
  • 氨基酸序列
    ADGPDAAAGNASQAQLQNNLNVGSDTTSETSFSLSKEAPREHLDHQAAHQPFPRPRFRQETGHPSLQRDFPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEADKDQHPENKPSWSVPSPDWRAWWQRSLSLARANSGDQDYKYDSTSDDSNFLNPPRGWDHTAPGHRTFETKDQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPNCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVMNDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDVLPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述:

    Recombinant Human ISM1 protein is a prokaryotic system E.coli expressed protein (Full Length of Mature Protein). To make this ISM1 recombinant protein, the ISM1 gene is synthesized and cloned into the E.coli system expression vector, and then it was transformed into protein-expressing host E Coli for expression, the other steps are testing for the identification of recombinant protein, large scale production and target protein Isolation and purification. The purity of the final ISM1 protein is 85%+ as determined by SDS-PAGE.

    ISM1 (also known as ISM or C20f82) is a protein encoding gene that provides an instruction in making a protein named Isthmin-1. isthmin-1 is a 52-kDa secreted protein with a thrombospondin type 1 repeat (TSR) domain, containing two consensus C-mannosylation sequences at Trp223 and Trp226 in human. This protein has a dual role in increasing adipose glucose uptake while suppressing hepatic lipid synthesis as an adipokine. It is also essential during organ development and active in parts of the immune response.

     

  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Acts as an angiogenesis inhibitor.
  • 基因功能參考文獻(xiàn):
    1. Our study demonstrates a successful pipeline from CNV identification of a candidate gene to functional validation in a vertebrate model system, and reveals Isthmin 1 as both a new human clefting locus as well as a key craniofacial patterning gene. PMID: 29162626
    2. Given that ISM1 has been reported to have anti-angiogenic properties, these observations suggest that ISM1 is a mediator of lymphocyte effector functions and may participate in both innate and acquired immune responses. PMID: 24956034
    3. Isthmin unexpectedly has both a pro-survival and death-promoting effect on endothelial cells depending on its physical state. PMID: 21544092
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Isthmin family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 16213

    OMIM: 615793

    KEGG: hsa:140862

    STRING: 9606.ENSP00000262487

    UniGene: Hs.559353



主站蜘蛛池模板: 丰满熟女人妻一区二区三 | 亚洲欧美在线一区中文字幕| 一区二区三区乱码在线 | 欧洲| 国产毛片久久久久久国产毛片| 解开人妻的裙子猛烈进入| 狼人亚洲国内精品自在线| 香蕉eeww99国产精选免费| 成人性生交大免费看| 亚洲精品久久久久久中文字幕 | 麻豆精品一区二区综合av| 色一情一乱一伦一区二区三区| 日本一道本高清一区二区| 少妇人妻无码专区在线视频| 国产偷亚洲偷欧美偷精品| 内射人妻视频国内| 97国产超碰一区二区三区| 精品免费国产一区二区三区四区介绍 | 少妇粉嫩小泬喷水视频www| 天堂资源中文网| 午夜无码性爽快影院6080| 美国人性欧美xxxx| 国产精品久久久影视青草| 国产成人综合久久精品推下载| 久久亚洲精品无码av宋| 亚洲综合色区中文字幕| 久久天天躁狠狠躁夜夜躁2014| a在线亚洲男人的天堂| 肉体裸交137日本大胆摄影| 欧美乱妇日本无乱码特黄大片| 亚洲国产精品无码专区| 国产区精品一区二区不卡中文| 99久久国产综合精品成人影院| 狠狠色噜噜狠狠狠888米奇视频 | 精品999日本久久久影院| 国产亚洲美女精品久久久2020| 亚洲妇熟xxxx妇色黄| 国产福利日本一区二区三区| 亚洲精品中文字幕一区二区三区| 乱中年女人伦| 国产成人欧美亚洲日韩电影| 国产制服丝袜欧美在线观看|