在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B)

  • 中文名稱:
    人IDH3B重組蛋白
  • 貨號:
    CSB-YP010992HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人IDH3B重組蛋白
  • 貨號:
    CSB-EP010992HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人IDH3B重組蛋白
  • 貨號:
    CSB-BP010992HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人IDH3B重組蛋白
  • 貨號:
    CSB-MP010992HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    IDH3B
  • Uniprot No.:
  • 別名:
    FLJ11043; H-IDHB; Idh3B; IDH3B_HUMAN; Isocitrate dehydrogenase [NAD] subunit beta; Isocitrate dehydrogenase [NAD] subunit beta; mitochondrial ; isocitrate dehydrogenase 3; beta subunit ; Isocitric dehydrogenase; Isocitric dehydrogenase subunit beta; MGC903; mitochondrial; NAD(+)-specific ICDH; NAD(+)-specific ICDH subunit beta; NAD+-specific isocitrate dehydrogenase b subunit ; NAD+-specific isocitrate dehydrogenase beta ; OTTHUMP00000030023; OTTHUMP00000030024; RP46
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    35-385
  • 氨基酸序列
    ASRSQA EDVRVEGSFP VTMLPGDGVG PELMHAVKEV FKAAAVPVEF QEHHLSEVQN MASEEKLEQV LSSMKENKVA IIGKIHTPME YKGELASYDM RLRRKLDLFA NVVHVKSLPG YMTRHNNLDL VIIREQTEGE YSSLEHESAR GVIECLKIVT RAKSQRIAKF AFDYATKKGR GKVTAVHKAN IMKLGDGLFL QCCEEVAELY PKIKFETMII DNCCMQLVQN PYQFDVLVMP NLYGNIIDNL AAGLVGGAGV VPGESYSAEY AVFETGARHP FAQAVGRNIA NPTAMLLSAS NMLRHLNLEY HSSMIADAVK KVIKVGKVRT RDMGGYSTTT DFIKSVIGHL QTKGS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
  • 基因功能參考文獻:
    1. Human NAD-dependent isocitrate dehydrogenase (IDH) is a heterotetrameric mitochondrial enzyme with 2alpha:1beta:1gamma subunit ratio subunits shich share 40-52% identity in amino acid sequence. PMID: 20435888
    2. IDPm activity appears to be modulated through enzymatic glutathionylation and deglutathionylation during oxidative stress PMID: 15653693
    3. Asp192 is needed for optimal affinity of IDH beta subunit for nicotinamide-adenine dinucleotide (NAD) substrate, but is not critical for catalysis. PMID: 17432878
    4. Homozygous for loss-of-function mutations in IDH3B is associated with retinitis pigmentosa. PMID: 18806796
    5. The point mutations of isocitrate dehydrogenase are essentially unique to gliomas. PMID: 19498431

    顯示更多

    收起更多

  • 相關疾病:
    Retinitis pigmentosa 46 (RP46)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    Isocitrate and isopropylmalate dehydrogenases family
  • 數據庫鏈接:

    HGNC: 5385

    OMIM: 604526

    KEGG: hsa:3420

    STRING: 9606.ENSP00000370223

    UniGene: Hs.436405



主站蜘蛛池模板: 欧洲熟妇色xxxx欧美老妇| 欧美成人看片一区二区| 天天躁夜夜躁狠狠是什么心态| 天堂va欧美va亚洲va好看va| 亚洲爆乳www无码专区| 国产999精品成人网站| 99re6热在线精品视频播放| 综合色就爱涩涩涩综合婷婷| 乱人伦视频中文字幕| 久久熟妇人妻午夜寂寞影院| 国产无遮挡又黄又爽又色| 可以直接免费观看的av网站| 都市激综合小说区另类区 | 女人被狂躁到高潮视频免费软件| 亚洲精品乱码久久久久蜜桃| 国内精品乱码卡一卡2卡麻豆| 日日av色欲香天天综合网| 亚洲成熟女人毛毛耸耸多| 老熟妇高潮一区二区三区| 亚洲综合久久一区二区| 综合图区亚洲欧美另类图片| 久精品视频在线观看免费 | 性欧美高清come| 在线欧美中文字幕农村电影| 夜夜躁狠狠躁日日躁2022| 国产乱人伦偷精品视频免| 污污又黄又爽免费的网站| 国产亚洲无线码一区二区| 欧美老熟妇又粗又大| 99精品偷自拍| 亚洲国产精品久久一线不卡| 一本一道久久a久久精品综合| 亚洲人精品亚洲人成在线| 久久人人97超碰国产精品| 三级理论中文字幕在线播放| 国产在线精品一区二区三区直播| 久久五月丁香激情综合| 在线高清亚洲精品二区| 久久久国产成人一区二区| 婷婷五月婷婷五月| 成人aa免费视频在线播放|