在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Intraflagellar transport protein 88 homolog (IFT88), partial

Recombinant Human Intraflagellar transport protein 88 homolog (IFT88), partial

  • 中文名稱：
    人IFT88重組蛋白
  • 貨號：
    CSB-YP618756HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人IFT88重組蛋白
  • 貨號：
    CSB-EP618756HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人IFT88重組蛋白
  • 貨號：
    CSB-EP618756HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人IFT88重組蛋白
  • 貨號：
    CSB-BP618756HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人IFT88重組蛋白
  • 貨號：
    CSB-MP618756HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    IFT88
  • Uniprot No.：
  • 別名：
    D13S1056E; DAF19; hTg737; Ift88; IFT88_HUMAN; Intraflagellar transport 88 homolog; Intraflagellar transport protein 88 homolog; MGC26259; Polaris homolog; Probe hTg737 (polycystic kidney disease; autosomal recessive); Recessive polycystic kidney disease protein Tg737 homolog; RP11-172H24.2; Tetratricopeptide repeat domain 10; Tetratricopeptide repeat protein 10; TG737; TPR repeat protein 10; TTC10
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
  • 基因功能參考文獻：
    1. BFGF also upregulated the mRNA and protein expression of IFT88 in primary cultured chondrocytes. PMID: 28901443
    2. Data suggest that the function of the fusion transcript crystallin, lambda 1 protein - intraflagellar transport 88 (CRYL1-IFT88) is closed to CRYL1 because it contained most of domain of CRYL1. PMID: 28489570
    3. multivariate Cox regression analyses demonstrated that Tg737 expression was an independent factor for predicting the overall survival of hepatocellular carcinoma patients PMID: 28663060
    4. MiR-548a-5p negatively regulates the tumor inhibitor gene Tg737 and promotes tumorigenesis in vitro and in vivo, indicating its potential as a novel therapeutic target for hepatocellular carcinoma. PMID: 27340352
    5. subtle regulation of IFT and associated cilia structure, tunes the wnt response controlling stem cell differentiation. PMID: 24346024
    6. this work suggests that Tg737 is involved in the invasion and migration of hepatoma cells under hypoxia, with the involvement of the polycystin-1, IL-8, and TGF-beta1 signaling pathway PMID: 22974282
    7. A mutation in IFT88 causes a hitherto unknown human ciliopathy. PMID: 22941275
    8. Data show that IFT88 depletion induces mitotic defects in human cultured cells, in kidney cells from the IFT88 mouse mutant Tg737(orpk) and in zebrafish embryos. PMID: 21441926
    9. The results indicate that loss of heterozygosity of the tumor suppressor gene Tg737 may play an important role in the carcinogenetic mechanism of liver cancer stem cells. PMID: 20300861
    10. IFT88 is a centrosomal protein regulating G1-S transition in non-ciliated cells. PMID: 17264151

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cell projection, cilium, flagellum.
  • 組織特異性：
    Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
  • 數據庫鏈接：

    HGNC: 20606

    OMIM: 600595

    KEGG: hsa:8100

    STRING: 9606.ENSP00000323580

    UniGene: Hs.187376



主站蜘蛛池模板： 乱子轮熟睡1区| 国产熟妇疯狂4p交在线播放| 香港台湾经典三级a视频| 99视频精品国产免费观看| 永久免费无码国产| 国产成人精品视频国产| 国产精品禁18久久久夂久| 精品国产三级a∨在线欧美| 亚洲狠狠婷婷综合久久| 69久久精品无码一区二区| 婷婷色婷婷开心五月| 中文字幕乱人伦高清视频| 色欲天天婬色婬香视频综合网| 国产精品一区二区 尿失禁| 无码人妻精品中文字幕免费东京热| 凸凹人妻人人澡人人添| 亚洲国产精品18久久久久久| 亚洲欧美成人综合图区| 国产在线观看免费人成视频| 被灌满精子的波多野结衣| 真实国产老熟女无套中出| 蜜桃视频一区二区在线观看| 丁香五月激情综合色婷婷| 在线va无卡无码高清| 亚洲精品国产一区二区的区别| 正在播放老肥熟妇露脸| 亚洲a片国产av一区无码| 国产 校园 另类 小说区| 免费国产污网站在线观看| av免费网站在线观看| 一本一道波多野结衣av黑人| 亚洲色自偷自拍另类小说| 久久综合狠狠综合久久综| 久久国产亚洲精选av| 人妻巨大乳一二三区| 久久发布国产伦子伦精品| 亚洲国产成人精品福利| 国产精品自在线拍亚洲另类| 国产老妇伦国产熟女老妇高清 | 成人爽a毛片免费网站| 伊人久久大香线蕉av仙人|