在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4),partial

In Stock
  • 中文名稱:
    人ITIH4重組蛋白
  • 貨號(hào):
    CSB-YP617923HU
  • 規(guī)格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP617923HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) ITIH4.
    • Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP617923HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) ITIH4.
    • The purity of ITIH4 was greater than 90% as determined by SEC-HPLC
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
    Greater than 90% as determined by SEC-HPLC.
  • 基因名:
  • Uniprot No.:
  • 別名:
    35 kDa inter-alpha-trypsin inhibitor heavy chain H4; gp120; H4P; IHRP; Inter-alpha-inhibitor heavy chain 4; Inter-alpha-trypsin inhibitor family heavy chain-related protein; Inter-alpha-trypsin inhibitor heavy chain H4; inter-alpha-trypsin inhibitor, heavy chain-like, 1; ITI heavy chain H4; ITI-HC4; ITIH4; ITIH4_HUMAN; ITIHL1; OTTHUMP00000197120; OTTHUMP00000197121; OTTHUMP00000213834; OTTHUMP00000213869; PK-120; PK120; Plasma kallikrein sensitive glycoprotein 120; PRO1851
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 來(lái)源:
    Yeast
  • 分子量:
    28.9 kDa
  • 表達(dá)區(qū)域:
    689-930aa
  • 氨基酸序列
    RLAILPASAPPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEGLRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDYQEGPPGVEISCWSVEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述:

    The fusion tag N-terminal 6xHis tag gene was added to the gene sequence corresponding to the yeast of the human ITIH4 protein to form the recombinant DNA. The recombinant DNA was cloned into the expression vector and then transfected into the yeast cells for expression. Following purification, the product is the recombinant human ITIH4 protein carrying N-terminal 6xHis tag. The SDS-PAGE assessed the purity of this recombinant ITIH4 protein up to 85%. It had an apparent molecular weight of approximately 30 kDa.

    ITIH4 is a gene encoding a protein called inter-alpha-trypsin inhibitor heavy chain H4 in human and belongs to ITIH family, which was associated with inflammation and carcinogenesis. This gene is located in a cluster of related inter alpha trypsin inhibitor genes on chromosome 14. The protein encoded by this gene is a 120 kDa acute-phase glycoprotein produced primarily in the liver. ITIH4 is involved in liver development and stabilization of the extracellular matrix (ECM), and its expression is altered in liver disease.

  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
  • 基因功能參考文獻(xiàn):
    1. Low ITIH4 expression is associated with Hepatocellular Carcinoma. PMID: 28828637
    2. this report has further supported for associations of genetic variants in the ITIH4 and CALN1 genes with schizophrenia and provided the first evidence that the variants regulate ITIH4 AND CALN1 expression in the dorsolateral prefrontal cortex PMID: 26991396
    3. ITIH4 peptide isoform as a preterm birth biomarker and its associated SNP implications PMID: 26408095
    4. Serum ITIH4 may be a PM10-specific biomarker in COPD and may be related to inflammation. PMID: 25977605
    5. Four novel body mass index-associated loci near the KCNQ1(rs2237892), ALDH2/MYL2 (rs671, rs12229654), ITIH4 (rs2535633) and NT5C2 (rs11191580) genes are identified in East Asian-ancestry populations. PMID: 24861553
    6. Worse survival among HCC patients with low ITIH4. PMID: 24836184
    7. Isoform-specific ITIH4 glycosylation and utilization of O-glycosylation sites on ITIH4 differs between cell lines and serum. PMID: 24884609
    8. Expression of the 85 kDa ITIH4 was substantial in amyotrophic lateral sclerosis compared with controls or patients with muscular dystrophy, Alzheimer diseases, or Parkinson diseases PMID: 23436019
    9. A truncated fragment of inter-alpha-trypsin inhibitor heavy chain 4 was the sole protein found to be significantly enhanced in the prostate cancer patients compared to the controls. PMID: 23417432
    10. Findings suggest that ITI-H4 expression may be used as a biomarker, which could facilitate the development of novel diagnostic and therapeutic tools. PMID: 21331437
    11. Genetic variation at ITIH4 locus is one of the likely candidate determinants for plasma cholesterol metabolisms PMID: 14661079
    12. ITIH4 and MTJ1 co-immunoprecipitate from total liver protein extracts and SANT domain of HTJ1 protects the ITIH4(588-930) recombinant fragment PMID: 16271702
    13. The inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) protein was significantly present more in interstial cystitis than controls PMID: 18455532
    14. ITIH4 is an anti-inflammatory protein, and suggests that further investigation into its potential use in the diagnosis and prognosis of acute ischemic stroke is warranted. PMID: 19263524

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    ITIH family
  • 組織特異性:
    Liver specific.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 6169

    OMIM: 600564

    KEGG: hsa:3700

    STRING: 9606.ENSP00000266041

    UniGene: Hs.709406



主站蜘蛛池模板: 720lu国产刺激无码| 中国精品少妇hd| 丰满诱人的人妻3| 99国产在线精品视频| 欧美婷婷六月丁香综合| 18禁美女裸体无遮挡免费观看国产| 欧美喷潮久久久xxxxx| 99久久国产热无码精品免费| 人妻无码中文字幕| 天天影视网天天综合色| 九九热爱视频精品视频16| 国产欧美va欧美va香蕉在线| 久久久无码一区二区三区| 男人扒开女人内裤强吻桶进去| 青青青国产在线视频在线观看 | 久久精品一本到东京热| 亚洲国产精品美女久久久久| 亚洲熟妇国产熟妇肥婆| 夜色福利院在线观看免费| 中文字幕精品亚洲无线码vr| 手机看片久久国产免费| 女人高潮内射99精品| 成人视频在线观看| 99热精品国自产拍天天拍| 午夜少妇性影院私人影院在线 | 国产乱子伦在线一区二区| 日韩欧美猛交xxxxx无码| 成人性做爰aaa片免费看| 女狠狠噜天天噜日日噜 | 国产三级做爰在线播放| 成年女人a毛片免费视频| 国产成人一区二区精品视频 | 狠狠色成人一区二区三区| 国产拍揄自揄免费观看| 无码人妻h动漫中文字幕| 中文字幕无码中文字幕有码| 亚洲 丝袜 制服 欧美 另类| 亚洲熟妇av日韩熟妇av| 夜夜添无码一区二区三区| av午夜久久蜜桃传媒软件| 午夜成人无码片在线观看影院|