在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Importin-4 (IPO4), partial

Recombinant Human Importin-4 (IPO4), partial

  • 中文名稱：
    人IPO4重組蛋白
  • 貨號(hào)：
    CSB-YP823474HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人IPO4重組蛋白
  • 貨號(hào)：
    CSB-EP823474HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人IPO4重組蛋白
  • 貨號(hào)：
    CSB-EP823474HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人IPO4重組蛋白
  • 貨號(hào)：
    CSB-BP823474HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人IPO4重組蛋白
  • 貨號(hào)：
    CSB-MP823474HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    IPO4
  • Uniprot No.：
  • 別名：
    Imp4; Imp4b; Importin 4; Importin 4b; Importin-4; Importin-4b; Ipo4; IPO4_HUMAN; Ran binding protein 4; Ran-binding protein 4; RanBP4
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
  • 基因功能參考文獻(xiàn)：
    1. Importins, Impbeta, Kapbeta2, Imp4, Imp5, Imp7, Imp9, and Impalpha, show the H3 tail binding more tightly than the H4 tail. The H3 tail binds Kapbeta2 and Imp5 with KD values of 77 and 57 nm, respectively, and binds the other five Importins more weakly. PMID: 27528606
    2. Study identified a core region encompassing nt - 118 to + 108 of IPO4 gene that is necessary for its promoter activity. Transcription factors binding to this region were screened, resulting in the identification of two members of the Ets family, Ets-like transcription factor-1 and GA binding protein, which repress or activate its promoter activity, respectively. PMID: 28254634
    3. report a function of IPO4 and nuclear import in the Fanconi anemia pathway of DNA repair PMID: 20805509
    4. demonstrated that vitamin D receptor (VDR) has two nuclear import systems: ligand-dependent & ligand-independent pathways, & that importin 4 fulfills the ligand-independent nuclear transport through the interaction with the amino terminus of VDR PMID: 16207705
    5. importins 4 and 7 accomplish nuclear import of HIF-1alpha more efficiently than the classical importin alpha/beta NLS receptor. PMID: 19788888

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Importin beta family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19426

    KEGG: hsa:79711

    STRING: 9606.ENSP00000346453

    UniGene: Hs.411865



主站蜘蛛池模板： 中文字幕乱码熟女人妻水蜜桃| 国产福利免费视频不卡| 日韩一区二区三区北条麻妃| 久久天天躁狠狠躁夜夜网站| 国产亚洲精品久久无码98| 久久精品囯产精品亚洲| 女人色极品影院| 国产激情久久久久久熟女老人| 狠狠色色综合网站| 亚州日本乱码一区二区三区| 国模冰莲自慰肥美胞极品人体图| 日韩人妻不卡一区二区三区| 久热这里只精品99国产6-99re视…| 国产成人精品男人的天堂| 国内精品人妻无码久久久影院蜜桃| 久久97超碰色中文字幕蜜芽| 日本少妇内射视频播放舔| 综合久久国产九一剧情麻豆| 乱子轮熟睡1区| 一个人看的日本hd免费| 无码丰满少妇2在线观看| 中文字幕精品av乱码在线| 99久久亚洲综合精品成人| 亚洲一区波多野结衣在线| 国精产品999一区二区三区有限| 无码人妻精品中文字幕| 国产精品a无线| 亚洲美女又黄又爽在线观看| 亚洲6080yy久久无码产自国产 | yy111111少妇无码影院| 亚洲日本在线电影| 高清一区二区三区免费视频| 亚洲国产精品久久久久秋霞小说| 日本午夜精品一区二区三区电影| 日本三级理论久久人妻电影| 国产亚洲精品aaaa片小说| 无码日韩精品一区二区人妻| 草草久久久无码国产专区| 人人妻人人澡av天堂香蕉| 国产精品爽爽va吃奶在线观看| 精品久久久久久无码人妻vr|