在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Hyaluronidase-3 (HYAL3)

  • 中文名稱:
    人HYAL3重組蛋白
  • 貨號(hào):
    CSB-YP010920HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人HYAL3重組蛋白
  • 貨號(hào):
    CSB-EP010920HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人HYAL3重組蛋白
  • 貨號(hào):
    CSB-EP010920HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人HYAL3重組蛋白
  • 貨號(hào):
    CSB-BP010920HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人HYAL3重組蛋白
  • 貨號(hào):
    CSB-MP010920HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    HYAL3
  • Uniprot No.:
  • 別名:
    Hyal-3; HYAL3; HYAL3_HUMAN; Hyaluronidase 3; Hyaluronidase-3; Hyaluronoglucosaminidase 3; Hyaluronoglucosaminidase-3; LUCA-3; LUCA14 ; LUCA3 ; Lung carcinoma protein 3; Minna14
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達(dá)區(qū)域:
    21-417
  • 氨基酸序列
    QPLPQVPERP FSVLWNVPSA HCEARFGVHL PLNALGIIAN RGQHFHGQNM TIFYKNQLGL YPYFGPRGTA HNGGIPQALP LDRHLALAAY QIHHSLRPGF AGPAVLDWEE WCPLWAGNWG RRRAYQAASW AWAQQVFPDL DPQEQLYKAY TGFEQAARAL MEDTLRVAQA LRPHGLWGFY HYPACGNGWH SMASNYTGRC HAATLARNTQ LHWLWAASSA LFPSIYLPPR LPPAHHQAFV RHRLEEAFRV ALVGHRHPLP VLAYVRLTHR RSGRFLSQDD LVQSIGVSAA LGAAGVVLWG DLSLSSSEEE CWHLHDYLVD TLGPYVINVT RAAMACSHQR CHGHGRCARR DPGQMEAFLH LWPDGSLGDW KSFSCHCYWG WAGPTCQEPR PGPKEAV
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Has no hyaluronidase activity in embryonic fibroblasts in vitro. Has no hyaluronidase activity in granulosa cells in vitro.
  • 基因功能參考文獻(xiàn):
    1. the relative expression of hyalurosome (CD44, HAS3, HB-EGF) genes was found to be reduced in patients prior to topical treatment and to be notably increased following treatment. PMID: 25138066
    2. mutations of the HYAL3 gene are rare in Chinese lung squamous cell carcinoma patients and might contribute to lymph node metastasis PMID: 23549009
    3. polymorphisms in HYAL3 are potentially involved in glaucomatous neurodegeneration. PMID: 22960332
    4. Nodular basal cell carcinoma is associated with increased levels of hyaluronic acid concomitant with upregulation of gene expression of HAS3, HYAL3 and RHAMM, when compared with normal adjacent skin. PMID: 20849445
    5. Overexpression of HYAL3 is associated with colorectal cancer. PMID: 20849597
    6. Hyal3 null sperm showed delayed cumulus penetration and reduced acrosomal exocytosis. PMID: 20586096
    7. Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3. PMID: 11929860
    8. Alternative mRNA splicing controls cellular expression of enzymatically active hyaluronidase. PMID: 12084718
    9. Down-regulation of HYAL3 is associated with small cell lung cancer and glioma PMID: 12684632

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted. Cell membrane. Cytoplasmic vesicle, secretory vesicle, acrosome. Endoplasmic reticulum. Early endosome.
  • 蛋白家族:
    Glycosyl hydrolase 56 family
  • 組織特異性:
    Expressed in sperm. Highly expressed in epidermis of the skin, where it is expressed intracellularily in the deep horny layer (at protein level). Bone marrow, testis and kidney.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5322

    OMIM: 604038

    KEGG: hsa:8372

    STRING: 9606.ENSP00000337425

    UniGene: Hs.129910



主站蜘蛛池模板: 亚洲色精品三区二区一区| 无码国内精品久久人妻| 日本乱子伦一区二区三区| 成 年 人 黄 色 大 片大 全| 精品无码中文视频在线观看| 日韩乱码人妻无码系列中文字幕| 久久久久久妓女精品影院| 国产一区二区无码蜜芽精品| 国产日产欧产精品精品app| 中文字幕在线不卡精品视频99 | 久久综合狠狠综合久久激情| 毛片免费全部播放无码| 级毛片内射视频| 国产日韩欧美久久久精品图片| 十八禁无码精品a∨在线观看| 超碰97人人让你爽| 亚洲一区二区三区四区五区六| 久久这里只精品国产免费10| 亚洲熟女综合一区二区三区| 成人无码精品一区二区三区| 国产综合有码无码中文字幕| 国产网红女主播精品视频| av在线播放日韩亚洲欧| 国产欧美精品一区二区三区-老狼| 少妇激情av一区二区三区 | 天天躁日日躁狠狠躁欧美老妇 | 国产福利在线视频蜜芽tv| 亚洲人成在线观看影院牛大爷| 国产亚洲日韩欧美另类丝瓜app | 在线成人精品国产区免费| 中文字幕乱码免费看电影| 猫咪www免费人成网站无码| 黄网站免费永久在线观看下载| 亚洲一区二区三区日本久久九| 国产激情久久久久久熟女老人| 三级在线看中文字幕完整版| 国产日产欧产精品精品免费| 深夜爽爽动态图无遮无挡| 亚洲情综合五月天| 欧美老熟妇喷水| 久久www成人看片免费不卡|