在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Homogentisate 1,2-dioxygenase (HGD)

In Stock
  • 中文名稱:
    人HGD重組蛋白
  • 貨號:
    CSB-EP842354HU
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    HGD
  • Uniprot No.:
  • 別名:
    2-dioxygenase; AKU; FLJ94126; hgd; HGD_HUMAN; HGO; Homogentisate 1 2 dioxygenase; Homogentisate 1; Homogentisate oxidase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    54.0 kDa
  • 表達區域:
    1-445aa
  • 氨基酸序列
    MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSWLYRILPSVSHKPFESIDEGQVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLKSHFTPNSRNPAEPN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Twelve novel HGD gene variants have been identified in 99 alkaptonuria patients affecting the bones. PMID: 25804398
    2. A novel alkaptonuria mutation, c.87 + 1G > A, shows a significant founder effect and high prevalence in a nomadic Indian population. PMID: 24575791
    3. study described two novel HGD mutations in a Chinese alkaptonuria family, the splicing mutation of IVS7 1G>C, a donor splice site of exon 7, and a missense mutation of F329C in exon 12 PMID: 23353776
    4. Report mutations of the HGD gene in Jordanian alkaptonuria patients. PMID: 21437689
    5. The observed increase of HGD expression in Alkaptonuria cells is probably due to a compensatory mechanism to overcome the almost null catalytic activity of the deficient enzyme PMID: 22105303
    6. An update on molecular genetics of Alkaptonuria (AKU).(review) PMID: 21720873
    7. Familiar ochronotic arthropathy is caused by a gene mutation of the homogentisic acid 1,2-dioxygenase (HGD) gene traced three hundred years in a Hungarian family. PMID: 20462779
    8. A comprehensive mutation analysis of 93 patients enrolled in this study, as well as an extensive update of all previously published HGD mutations associated with alkaptonuria, is reported. PMID: 19862842
    9. Turkish mutation shares an homogentisate 1,2-dioxygenase haplotype with the mutation found in Finland, Slovakia and India, suggesting that R58fs is an old alkaptonuria mutation that probably originated in central Asia PMID: 12872836
    10. Four different mutations of the HGD gene were found in alkaptonuria and ochronotic arthropathy diagnoses. PMID: 16085442
    11. A single nucleotide deletion located in exon 3 resulted in a frameshift mutation in HGD gene in family with alkaptonuria. PMID: 18945288

    顯示更多

    收起更多

  • 相關疾病:
    Alkaptonuria (AKU)
  • 蛋白家族:
    Homogentisate dioxygenase family
  • 組織特異性:
    Highest expression in the prostate, small intestine, colon, kidney and liver.
  • 數據庫鏈接:

    HGNC: 4892

    OMIM: 203500

    KEGG: hsa:3081

    STRING: 9606.ENSP00000283871

    UniGene: Hs.368254



主站蜘蛛池模板: 青青草99久久精品国产综合| 欧美黑人性暴力猛交喷水黑人巨大| 尤物av无码国产在线看| 精品无码一区在线观看| 中国熟妇人妻xxxxx| 少妇熟女高潮流白浆| 在线观看黄a∨免费无毒网站 | 色欲一区二区三区精品a片| 十八禁真人啪啪免费网站| 国内精品久久久久久影院8f | 一道久久爱综合久久爱| 男人av无码天堂| 国产一区二区三区精品av| 亚洲.欧美.在线视频| 黑人巨大精品欧美| 欧美xxxxx高潮喷水麻豆| 少妇mm被擦出白浆液视频| aⅴ亚洲 日韩 色 图网站 播放| 中文字幕丰满乱子伦无码专区| 免费观看的av在线播放| 欧美极品video粗暴| 丁香五月激情综合亚洲| 少妇人妻丰满做爰xxx| 亚洲中文字幕无码爆乳app| 饥渴少妇做私密保健视频| 一区二区三区无码按摩精油| 国产亚洲成av人片在线观黄桃| 久久99精品国产99久久6尤物| 亚洲欧洲自拍拍偷精品网| 无码潮喷a片无码高潮视频| 精品无码无人网站免费视频| 中文字幕三级人妻无码视频| 国产av无码专区亚洲aⅴ| 人妻无码中文久久久久专区| 国产高清av在线播放| 高清av熟女一区| 又大又硬又黄的免费视频| 成人免费的视频| 久久九九有精品国产23百花影院 | 国产97在线 | 免费| 亚洲综合色区另类小说|