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  4. Recombinant Human Homeobox protein BarH-like 2 (BARX2)

Recombinant Human Homeobox protein BarH-like 2 (BARX2)

  • 中文名稱：
    Recombinant Human Homeobox protein BarH-like 2(BARX2)
  • 貨號：
    CSB-YP891557HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Homeobox protein BarH-like 2(BARX2)
  • 貨號：
    CSB-EP891557HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Homeobox protein BarH-like 2(BARX2)
  • 貨號：
    CSB-EP891557HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Homeobox protein BarH-like 2(BARX2)
  • 貨號：
    CSB-BP891557HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Homeobox protein BarH-like 2(BARX2)
  • 貨號：
    CSB-MP891557HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BARX2
  • Uniprot No.：
  • 別名：
    BarH like homeobox 2; BarX 2; BARX homeobox; BARX homeobox 2; Barx2; BARX2_HUMAN; Homeobox protein BarH like 2; Homeobox protein BarH-like 2; MGC133368; MGC133369
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-279
  • 氨基酸序列
    MHCHAELRLS SPGQLKAARR RYKTFMIDEI LSKETCDYFE KLSLYSVCPS LVVRPKPLHS CTGSPSLRAY PLLSVITRQP TVISHLVPAT PGIAQALSCH QVTEAVSAEA PGGEALASSE SETEQPTPRQ KKPRRSRTIF TELQLMGLEK KFQKQKYLST PDRLDLAQSL GLTQLQVKTW YQNRRMKWKK MVLKGGQEAP TKPKGRPKKN SIPTSEEIEA EEKMNSQAQG QEQLEPSQGQ EELCEAQEPK ARDVPLEMAE PPDPPQELPI PSSEPPPLS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia.
  • 基因功能參考文獻：
    1. These findings reveal that Barx2 serving as a tumor suppressor gene could decrease cell proliferation, migration, and aerobic glycolysis through inhibiting the Wnt/beta-catenin signaling pathway, and predicts a good prognosis in non-small cell lung carcinoma PMID: 29341468
    2. these findings indicate that reduction or loss of Barx2 dis-inhibits gastric cancer cell proliferation and invasion, and that reduction in Barx2 could serve as an independent prognostic biomarker for poor outcome in gastric cancer patients PMID: 27533254
    3. Down-regulation of Barx2 is associated with advanced clinical factors of colorectal cancer and predicts poor survival. PMID: 27453340
    4. BARX2 can coordinate the expression of a network of genes that influence the growth of tumor cells PMID: 14744868
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    BAR homeobox family
  • 組織特異性：
    Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta.
  • 數據庫鏈接：

    HGNC: 956

    OMIM: 604823

    KEGG: hsa:8538

    STRING: 9606.ENSP00000281437

    UniGene: Hs.591944



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