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  4. Recombinant Human Golgin subfamily A member 3 (GOLGA3), partial

Recombinant Human Golgin subfamily A member 3 (GOLGA3), partial

  • 中文名稱：
    人GOLGA3重組蛋白
  • 貨號：
    CSB-YP600096HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GOLGA3重組蛋白
  • 貨號：
    CSB-EP600096HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GOLGA3重組蛋白
  • 貨號：
    CSB-EP600096HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GOLGA3重組蛋白
  • 貨號：
    CSB-BP600096HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GOLGA3重組蛋白
  • 貨號：
    CSB-MP600096HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    GOLGA3Golgin subfamily A member 3; Golgi complex-associated protein of 170 kDa; GCP170; Golgin-160
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Golgi auto-antigen; probably involved in maintaining Golgi structure.
  • 基因功能參考文獻：
    1. The golgin-160 binds directly to the third intracellular loop of beta1AR and that this binding depends on three basic residues in this loop. PMID: 24566136
    2. Golgi protein golgin160 recruits dynein to Golgi membranes. PMID: 22814606
    3. A common epitope of proteins golgin-160, voltage-gated potassium channel and disulfide isomerase was identified by screening with autoantibodies of a type 1 diabetic patient PMID: 20170975
    4. NH2 terminal domain of Golgin 160 has a role in nuclear transport and Golgi apparatus localization PMID: 12130652
    5. results indicate that GCP16 is the acylated membrane protein, associated with GCP170, and possibly involved in vesicular transport from the Golgi to the cell surface PMID: 14522980
    6. Caspase-resistant GOLGA3 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors. PMID: 15829563
    7. golgin-160 assosiates in an isoform-specific manner with the Golgi-associated protein PIST PMID: 15951434
    8. GCP60 interacts preferentially with one of the golgin-160 caspase cleavage fragments (residues 140-311). This strong interaction prevented the golgin-160 fragment from accumulating in the nucleus when this fragment and GCP60 were overexpressed. PMID: 16870622
    9. golgin-160 may promote efficient surface delivery of a subset of cargo molecules PMID: 17118120
    10. nuclear translocation of golgin-160-(140-311) is a highly coordinated event regulated not only by cleavage of the golgin-160 head but also by the oxidation state of GCP60 PMID: 17711851

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  • 亞細胞定位：
    Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
  • 組織特異性：
    Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.
  • 數據庫鏈接：

    HGNC: 4426

    OMIM: 602581

    KEGG: hsa:2802

    STRING: 9606.ENSP00000204726

    UniGene: Hs.507333



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