在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Golgi SNAP receptor complex member 1 (GOSR1), partial

  • 中文名稱:
    人GOSR1重組蛋白
  • 貨號:
    CSB-YP009677HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GOSR1重組蛋白
  • 貨號:
    CSB-EP009677HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GOSR1重組蛋白
  • 貨號:
    CSB-EP009677HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GOSR1重組蛋白
  • 貨號:
    CSB-BP009677HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GOSR1重組蛋白
  • 貨號:
    CSB-MP009677HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GOSR1
  • Uniprot No.:
  • 別名:
    GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
  • 基因功能參考文獻:
    1. these results indicate that GS28 nuclear predominant expression could serve as a prognostic marker for colorectal cancer (CRC) and may help in identifying aggressive forms of CRC PMID: 28638266
    2. High nuclear expression of GS28 is associated with poor prognosis in early-stage cervical cancer patients. GS28 might be a novel prognostic marker and a potential therapeutic target in cervical cancer treatment. PMID: 27611086
    3. Golgi vesicles, presumably with COPI, serve to inhibit intra-Golgi transport by the extraction of GS27 and GS28 from the Golgi cisternae, which blocks the formation of inter-cisternal connections PMID: 23387339
    4. GS28 may potentiate cells to DNA-damage-induced apoptosis by inhibiting the ubiquitination and degradation of p53. PMID: 22397410
    5. ORP7 negatively regulates GS28 protein stability via sequestration of GATE-16, and may mediate the effect of 25-OH on GS28 and Golgi function. PMID: 21669198
    6. Apolipoprotein E, growth factor receptor-bound protein 2, Golgi SNAP receptor complex member 1, and glucosidase, beta, acid may play a neurodegenerative role in stress urinary incontinence development. PMID: 20700730
    7. Data suggest that GS15 exists in a distinct SNARE complex that contains syntaxin5, GS28, and Ykt6, and may be involved in both ER-to-Golgi and intra-Golgi transport. PMID: 12388752

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus membrane; Single-pass type IV membrane protein.
  • 蛋白家族:
    GOSR1 family
  • 數據庫鏈接:

    HGNC: 4430

    OMIM: 604026

    KEGG: hsa:9527

    STRING: 9606.ENSP00000225724

    UniGene: Hs.462680



主站蜘蛛池模板: 茄子视频国产在线观看| 乱中年女人伦av二区| 精品无码久久久久国产电影| 久久久亚洲欧洲日产国码二区| 国产色秀视频在线播放| 亚洲成a∨人片在线观看不卡| 影音先锋男人站| 国产在线观看免费视频软件| 99热在线精品国产观看| 人人插人人插人人爽| 国产一区二区三区四区五区vm| 国产精品麻豆成人av网| 无码av专区丝袜专区| wwww亚洲熟妇久久久久| 精品无码一区二区三区爱欲| 成人做爰视频www网站| 国产午夜鲁丝片av无码| 性色av无码一区二区三区人妻| 亚洲乱码无码永久不卡在线| 国产成人亚洲精品无码最新| 宝宝好涨水快流出来免费视频| 亚洲成a人v影院色老汉影院| 久久亚洲精品国产精品777777| 国产在线精品欧美日韩电影| 中国极品少妇videossexhd| 看成年女人午夜毛片免费| 69成人免费视频无码专区| 日韩乱码人妻无码中文视频| 97色偷偷色噜噜狠狠爱网站| 狠狠做深爱婷婷丁香综合| 52综合精品国产二区无码| 午夜福利电影| 成人做爰视频www网站小优视频| 噜噜噜av久久| 国产玉足榨精视频在线观看| 熟妇人妻久久中文字幕| 蜜色欲多人av久久无码| 中国老熟女重囗味hdxx| 欧美性受xxxx黑人xyx性爽| 国产性―交―乱―色―情人 | 国内无遮挡18禁无码网站免费|