在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Glycine dehydrogenase [decarboxylating], mitochondrial (GLDC), partial

Recombinant Human Glycine dehydrogenase [decarboxylating], mitochondrial (GLDC), partial

  • 中文名稱：
    人GLDC重組蛋白
  • 貨號：
    CSB-YP328400HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GLDC重組蛋白
  • 貨號：
    CSB-EP328400HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GLDC重組蛋白
  • 貨號：
    CSB-EP328400HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GLDC重組蛋白
  • 貨號：
    CSB-BP328400HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GLDC重組蛋白
  • 貨號：
    CSB-MP328400HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GLDC
  • Uniprot No.：
  • 別名：
    GCE; GCSP; GCSP_HUMAN; GLDC; Glycine cleavage system P protein; glycine cleavage system protein P; Glycine decarboxylase; glycine decarboxylase P protein ; Glycine dehydrogenase (decarboxylating) mitochondrial; Glycine dehydrogenase [decarboxylating]; mitochondrial; Gycine dehydrogenase (decarboxylating); HYGN1; MGC138198; MGC138200; NKH
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH).
  • 基因功能參考文獻：
    1. A novel compound heterozygous variant was identified in the GLDC gene in a Chinese family with non-ketotic hyperglycinemia PMID: 29304759
    2. it was concluded that elevated serum GLDC may increase lung cancer risk, and that smoking, GLDC, the miR29 family and DNMT signaling pathways may serve an important role in early malignant transformation during the development of lung cancer. PMID: 29956770
    3. a comprehensive functional and structural analysis of 19 GLDC missense variants identified in a cohort of 26 nonketotic hyperglycinemia patients was performed PMID: 28244183
    4. The position and frequency of the breakpoint for CNVs correlated with intron size and presence of Alu elements. Missense mutations, most often recurring, were the most common type of disease-causing mutation in AMT PMID: 27362913
    5. We show that the combination of GLDC and HIF-1alpha expression is an independent prognostic factor in early-stage lung non-small cell cancer PMID: 28062918
    6. study reports a novel mutation, c.2296G>T (p.Gly766Cys), in exon 19 of the glycine decarboxylase (GLDC) gene in a consanguineous Indian couple with a history of 4 neonatal deaths PMID: 23349517
    7. Identification of a splice acceptor site mutation and five different non-synonymous variants in GLDC were found in patients with neural tube defects. PMID: 22171071
    8. Study shows that glycine metabolism and the metabolic enzyme glycine decarboxylase (GLDC) drive tumor-initiating cells and tumorigenesis in non-small cell lung cancer. PMID: 22225612
    9. Heterozygous GLDC gene mutation in transient neonatal hyperglycinemia. PMID: 12402263
    10. Missense and nonsense mutations found in glycine encephalopathy PMID: 14552331
    11. Three adults with mild hyperglycinemia, infantile hypotonia, mental retardation, behavioral hyperirritability, and aggressive outbursts were screened for glycine decarboxylase mutations; two novel missense mutations were found. PMID: 15824356
    12. The mutation in this nonketotic hyperglycinemia kindred led to missplicing and reduced GLDC (glycine decarboxylase) expression. PMID: 15851735
    13. Single nucleotide substitution that abolishes the initiator methionine codon of the GLDC gene is associated with glycine encephalopathy PMID: 15864413
    14. the nonketotic hyperglycinemia is due to a novel GLDC mutation. PMID: 16404748
    15. forty different gene alterations in the GLDC gene were identified in patients with glycine encephalopathy PMID: 16601880
    16. A screening system for GLDC deletions by multiplex ligation-dependent probe amplification identified 14 deletions of different length & Alu-mediated recombination in non-ketotic hyperglycinaemia patients. PMID: 17361008
    17. a histidine-to-aspartic acid change at amino acid position 371 (p. His371Asp mutation) in the glycine decarboxylase in a non-ketotic hyperglycemia patient. PMID: 18581728

    顯示更多

    收起更多

  • 相關疾病：
    Non-ketotic hyperglycinemia (NKH)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    GcvP family
  • 數據庫鏈接：

    HGNC: 4313

    OMIM: 238300

    KEGG: hsa:2731

    STRING: 9606.ENSP00000370737

    UniGene: Hs.584238



主站蜘蛛池模板： 欧美日本国产va高清cabal| 色偷偷色噜噜狠狠网站年轻人 | а√在线中文网新版地址在线 | 好爽…又高潮了免费毛片| 中国国产野外1级毛片视频| 国产超薄肉色丝袜视频| 爆乳护士一区二区三区在线播放| 亚洲国内成人精品网| √天堂中文官网8在线| 亚洲h在线播放在线观看h| 亚洲妇女行蜜桃av网网站| 国产精品毛片在线完整版| 小13箩利洗澡无码视频网站| 久久久久成人精品免费播放动漫 | 久热中文字幕无码视频| 欧美综合在线激情专区| 国产精品特级毛片一区二区三区 | 亚洲大乳高潮日本专区| 日本熟妇美熟bbw| 小宝极品内射国产在线| 欧美性xxxx狂欢老少配| 亚洲色成人网站永久| 亚洲成年轻人电影网站www| 加勒比久久综合网天天| 精品久久久久久无码国产| 男人和女人高潮做爰视频| 精品无码一区二区三区的天堂| 巨胸不知火舞露双奶头无遮挡| 黑人大战中国av女叫惨了| 人人澡人人澡人人看添av| 99re6热在线精品视频播放| 色综合99久久久无码国产精品| 秋霞最新高清无码鲁丝片| 亚洲精品国产av成拍色拍婷婷 | 18成禁人视频免费| 欧精国精产品一区| 亚洲经典三级| 婷婷五月俺也去人妻| 午夜亚洲国产理论片中文| 色欲国产麻豆一精品一av一免费| 少妇熟女视频一区二区三区|