Recombinant Human GTP-binding protein REM 1 (REM1)

中文名稱：

人REM1重組蛋白
貨號：

CSB-YP019559HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人REM1重組蛋白
貨號：

CSB-EP019559HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人REM1重組蛋白
貨號：

CSB-EP019559HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人REM1重組蛋白
貨號：

CSB-BP019559HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人REM1重組蛋白
貨號：

CSB-MP019559HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

REM1
Uniprot No.：

O75628
別名：

E030011C07Rik; GD:REM; GES; GTP binding protein REM ; GTP binding protein REM 1; GTP binding protein REM1; GTP-binding protein REM 1; GTPase GES; GTPase regulating endothelial cell sprouting; GTPase-regulating endothelial cell sprouting; MGC114556; MGC48669; OTTMUSP00000016855; Rad and Gem like GTP binding protein 1; Rad and Gem-like GTP-binding protein 1; RAS (RAD and GEM) like GTP binding ; RAS like GTP binding; RAS like GTP binding protein REM; REM 1; Rem1; REM1_HUMAN; RP23-35I8.9
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達(dá)區(qū)域：

1-298
氨基酸序列

MTLNTEQEAK TPLHRRASTP LPLSPRGHQP GRLSTVPSTQ SQHPRLGQSA SLNPPTQKPS PAPDDWSSES SDSEGSWEAL YRVVLLGDPG VGKTSLASLF AGKQERDLHE QLGEDVYERT LTVDGEDTTL VVVDTWEAEK LDKSWSQESC LQGGSAYVIV YSIADRGSFE SASELRIQLR RTHQADHVPI ILVGNKADLA RCREVSVEEG RACAVVFDCK FIETSATLQH NVAELFEGVV RQLRLRRRDS AAKEPPAPRR PASLAQRARR FLARLTARSA RRRALKARSK SCHNLAVL
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.
基因功能參考文獻(xiàn)：
1. We conclude that Rem is capable of regulating L-type current, that release of Rem block is modulated by cellular kinase pathways, and that the Ca(V)1.2 COOH terminus contributes to Rem-dependent channel inhibition. PMID: 16648185
2. a role for the Rem C terminus in plasma membrane localization through association with phosphatidylinositol lipids. PMID: 17686775
蛋白家族：

Small GTPase superfamily, RGK family
組織特異性：

Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in
數(shù)據(jù)庫鏈接：

HGNC: 15922

OMIM: 610388

KEGG: hsa:28954

STRING: 9606.ENSP00000201979

UniGene: Hs.247729