在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human GDP-mannose 4,6 dehydratase (GMDS)

  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-YP009569HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-EP009569HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-EP009569HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-BP009569HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-MP009569HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GMDS
  • Uniprot No.:
  • 別名:
    GDP D mannose dehydratase; GDP mannose 4 6 dehydratase; GDP-D-mannose dehydratase; GDP-mannose 4,6 dehydratase; GMD; Gmds; GMDS_HUMAN; OTTHUMP00000017756; OTTHUMP00000232770; SDR3E1; Short chain dehydrogenase/reductase family 3E member 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-372
  • 氨基酸序列
    AHAPARCPS ARGSGDGEMG KPRNVALITG ITGQDGSYLA EFLLEKGYEV HGIVRRSSSF NTGRIEHLYK NPQAHIEGNM KLHYGDLTDS TCLVKIINEV KPTEIYNLGA QSHVKISFDL AEYTADVDGV GTLRLLDAVK TCGLINSVKF YQASTSELYG KVQEIPQKET TPFYPRSPYG AAKLYAYWIV VNFREAYNLF AVNGILFNHE SPRRGANFVT RKISRSVAKI YLGQLECFSL GNLDAKRDWG HAKDYVEAMW LMLQNDEPED FVIATGEVHS VREFVEKSFL HIGKTIVWEG KNENEVGRCK ETGKVHVTVD LKYYRPTEVD FLQGDCTKAK QKLNWKPRVA FDELVREMVH ADVELMRTNP NA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
  • 基因功能參考文獻:
    1. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS). PMID: 25173105
    2. These data demonstrate involvement of GMDS mutation in the progression of colorectal cancer. PMID: 23922970
    3. Fx enzyme and GDP-L-Fuc Tr overexpression in the tumur tissue of colorectal cancer (CRC) patients suggests that GDP-L-Fuc transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC. PMID: 23730929
    4. GMD inhibits tankyrase 1 poly(ADP-ribose) polymerase activity in vitro, dependent on the GMD tankyrase 1 binding motif. In vivo, depletion of GMD led to degradation of tankyrase 1, dependent on the catalytic PARP activity of tankyrase 1. PMID: 22645305
    5. Results indicate that GMDS regulates the formation of secondary complex II from the primary DISC independent of direct fucosylation of death receptors. PMID: 22027835
    6. FX takes part in the cascade of events leading to the extravasation of activated lymphocytes. PMID: 11831876
    7. Deficiency of GMDS leads to escape from natural killer cell-mediated tumor surveillance through modulation of TRAIL signaling. PMID: 19361506

    顯示更多

    收起更多

  • 蛋白家族:
    NAD(P)-dependent epimerase/dehydratase family, GDP-mannose 4,6-dehydratase subfamily
  • 數據庫鏈接:

    HGNC: 4369

    OMIM: 602884

    KEGG: hsa:2762

    STRING: 9606.ENSP00000370194

    UniGene: Hs.144496



主站蜘蛛池模板: 久久无码中文字幕无码| 国偷自产av一区二区三区| 亚洲中文字幕久久无码精品| 亚洲日韩国产精品乱-久| 国产日韩av一区二区三区五区| 国产精品无码一区二区三区在| 日韩成人一区二区三区在线观看| 国产香蕉尹人在线视频你懂的| 成在人线av无码免费看网站直播| 国产一区二区三区内射高清| 国产乱妇乱子视频在播放| 亚洲另类成人小说综合网 | 中文字幕亂倫免賛視頻| 久久精品无码av| 在线观看免费人成视频色9| 直接观看黄网站免费视频| 无人区一线二线三线乱码| 99久久人妻精品免费一区| 天天弄天天模| 精品久久一区二区乱码| 在线亚洲专区高清中文字幕| 免费裸体美女网站| 色婷婷久久久swag精品| 久久无码超清激情av| 五月丁香综合激情六月久久| 色一情一区二区三区四区| 国产精品自产拍在线18禁| 国产精品极品在线拍| 亚洲精品中文字幕乱码三区| 久久香蕉超碰97国产精品| 亚洲国产超清无码专区| 香蕉久久人人爽人人爽人人片av| 天天天欲色欲色www免费| 大j8黑人w巨大888a片| 日本xxxx片免费观看| 久久99亚洲精品久久99果| 久久熟妇人妻午夜寂寞影院| 人妻系列无码一区二区三区| 欧美老熟妇乱子伦视频| 国产在线观看无码的免费网站| 人狥杂交一区欧美二区|