在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human GDP-mannose 4,6 dehydratase (GMDS)

  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-YP009569HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-EP009569HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-EP009569HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-BP009569HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GMDS重組蛋白
  • 貨號:
    CSB-MP009569HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GMDS
  • Uniprot No.:
  • 別名:
    GDP D mannose dehydratase; GDP mannose 4 6 dehydratase; GDP-D-mannose dehydratase; GDP-mannose 4,6 dehydratase; GMD; Gmds; GMDS_HUMAN; OTTHUMP00000017756; OTTHUMP00000232770; SDR3E1; Short chain dehydrogenase/reductase family 3E member 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-372
  • 氨基酸序列
    AHAPARCPS ARGSGDGEMG KPRNVALITG ITGQDGSYLA EFLLEKGYEV HGIVRRSSSF NTGRIEHLYK NPQAHIEGNM KLHYGDLTDS TCLVKIINEV KPTEIYNLGA QSHVKISFDL AEYTADVDGV GTLRLLDAVK TCGLINSVKF YQASTSELYG KVQEIPQKET TPFYPRSPYG AAKLYAYWIV VNFREAYNLF AVNGILFNHE SPRRGANFVT RKISRSVAKI YLGQLECFSL GNLDAKRDWG HAKDYVEAMW LMLQNDEPED FVIATGEVHS VREFVEKSFL HIGKTIVWEG KNENEVGRCK ETGKVHVTVD LKYYRPTEVD FLQGDCTKAK QKLNWKPRVA FDELVREMVH ADVELMRTNP NA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
  • 基因功能參考文獻:
    1. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS). PMID: 25173105
    2. These data demonstrate involvement of GMDS mutation in the progression of colorectal cancer. PMID: 23922970
    3. Fx enzyme and GDP-L-Fuc Tr overexpression in the tumur tissue of colorectal cancer (CRC) patients suggests that GDP-L-Fuc transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC. PMID: 23730929
    4. GMD inhibits tankyrase 1 poly(ADP-ribose) polymerase activity in vitro, dependent on the GMD tankyrase 1 binding motif. In vivo, depletion of GMD led to degradation of tankyrase 1, dependent on the catalytic PARP activity of tankyrase 1. PMID: 22645305
    5. Results indicate that GMDS regulates the formation of secondary complex II from the primary DISC independent of direct fucosylation of death receptors. PMID: 22027835
    6. FX takes part in the cascade of events leading to the extravasation of activated lymphocytes. PMID: 11831876
    7. Deficiency of GMDS leads to escape from natural killer cell-mediated tumor surveillance through modulation of TRAIL signaling. PMID: 19361506

    顯示更多

    收起更多

  • 蛋白家族:
    NAD(P)-dependent epimerase/dehydratase family, GDP-mannose 4,6-dehydratase subfamily
  • 數據庫鏈接:

    HGNC: 4369

    OMIM: 602884

    KEGG: hsa:2762

    STRING: 9606.ENSP00000370194

    UniGene: Hs.144496



主站蜘蛛池模板: 亚洲欧洲日产最新| 日本成本人片免费网站 | 亚洲国产中文在线二区三区免 | 无码av永久免费专区麻豆| 色婷婷综合缴情综免费观看| 肥老熟妇伦子伦456视频| 无码中文av有码中文av| 亚洲熟女精品中文字幕| 麻豆成人久久精品二区三区免费| 亚洲欧美国产国产一区二区三区 | 77se77亚洲欧美在线| 国产午夜鲁丝片av无码免费| 久久久久人妻一区精品| 在线永久免费观看黄网站| 天堂俺去俺来也www色官网| 中文字幕av无码人妻| 国产内射爽爽大片| 少妇私密会所按摩到高潮呻吟| 无码午夜成人1000部免费视频| 国产精品亚洲二区在线播放| 欧美精品亚洲精品日韩专区一乛方| 国产成年无码v片在线| av无码精品一区二区三区| 亚欧免费无码aⅴ在线观看蜜桃 | 亚洲精品久久久一二三区| 狂野欧美激情性xxxx在线观看| 内射人妻少妇无码一本一道| 奇米影视第4色| 色妞精品av一区二区三区| 国产美女视频免费观看网址| 免费拍拍拍网站| 国产精品视频白浆免费视频| 粗大的内捧猛烈进出少妇视频| 欧美丰满老熟妇乱叫| 女人另类牲交zozozo| 狠狠色噜噜狠狠狠888米奇视频| 18禁勿入网站入口永久| 欧美成人高清视频a在线看| 国产欧美日韩一区二区三区| 欧美亚洲一区二区三区| 西西444www大胆无码视频|