在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human G-protein coupled receptor 15 (GPR15), partial

Recombinant Human G-protein coupled receptor 15 (GPR15), partial

  • 中文名稱：
    人GPR15重組蛋白
  • 貨號：
    CSB-YP009764HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GPR15重組蛋白
  • 貨號：
    CSB-EP009764HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GPR15重組蛋白
  • 貨號：
    CSB-EP009764HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GPR15重組蛋白
  • 貨號：
    CSB-BP009764HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GPR15重組蛋白
  • 貨號：
    CSB-MP009764HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    GPR15; G-protein coupled receptor 15; Brother of Bonzo; BoB
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.
  • 基因功能參考文獻：
    1. we for the first time demonstrated that TM binds to GPR15 via its EGF-like domain and exerts angiogenesis and cytoprotective function in vascular ECs. PMID: 28386128
    2. Results suggested that Ser-357 phosphorylation critically controls the ligand-independent endocytosis of GPR15. The functional role of Ser-357 in endocytosis was distinct from that of a conserved Ser/Thr cluster in the more proximal C-terminus, which was responsible for the beta-arrestin- and GPCR kinase-dependent endocytosis of GPR15. PMID: 28615320
    3. Analysis of GPR15 methylation identified significantly greater hypomethylation in smokers compared with that in never-smokers. PMID: 26348578
    4. infection-induced up-regulation of GPR15 expression through TLR3 could increase susceptibility of CD4(+) T cells to HIV infection and target cell availability in the gut in some infected individuals PMID: 24558379
    5. Data indicate that orphan receptor GPR15/BOB is expressed by macrophages in synovial tissue and on monocytes and neutrophils in peripheral blood, and expression is up-regulated in arthritis (RA)patients PMID: 24725539
    6. GPR15 expression was minimal in lymphocytes from the blood and the small intestine; however, it was expressed at high levels in lymphocytes from the large intestine PMID: 23661644
    7. C-terminal membrane-proximal basic residues have a role in cell surface trafficking of HIV coreceptor GPR15 protein PMID: 23430259
    8. 14-3-3 proteins play multiple roles in biogenesis and trafficking of an HIV co-receptor GPR15 to control its cell surface density in response to the phosphorylation signal PMID: 21189250
    9. role of GPR15-HIV1 gp120 interactions in gp120 binding to intestinal epithelial cells and gp120-induced cytopathic effects PMID: 12566994
    10. HIV-2 isolates from aviremic and viremic individuals commonly use as coreceptors CCR5, GPR15, and CXCR6 PMID: 15650194

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：

    HGNC: 4469

    OMIM: 601166

    KEGG: hsa:2838

    STRING: 9606.ENSP00000284311

    UniGene: Hs.162987



主站蜘蛛池模板： 蜜桃av亚洲精品一区二区| √最新版天堂资源网在线下载 | 国产人与禽zoz0性伦| 久久久久国产精品人妻aⅴ天堂 | 无码人妻久久一区二区三区 | 日韩成人一区二区三区在线观看| 成人区精品一区二区婷婷| 亚洲高清无码加勒比| 免费大片av手机看片不卡| 18禁又污又黄又爽的网站不卡| 99在线在线视频观看| 人妻少妇一区二区三区| 亚洲va中文字幕无码久久| 成人爽a毛片免费看| 国产下药迷倒白嫩美女网站| 最新日韩精品中文字幕| 久久天天躁狠狠躁夜夜网站| 日本丰满少妇高潮呻吟| 国产精品毛片在线完整版| 中日产幕无线码一区| 在线播放免费人成视频在线观看| 小雪尝禁果又粗又大的视频| 亚洲伊人久久大香线蕉| 亚洲乱码卡一卡二卡新区仙踪木木| 午夜福利92国语| 精品av无码国产一区二区| 99麻豆久久久国产精品免费| 国内精品久久久久影院网站| 嫩草国产露脸精品国产软件| 欧洲精品码一区二区三区免费看| aa片在线观看视频在线播放| 久久久久免费看成人影片| 国产成人综合一区人人| 一边吃奶一边做动态图| 亚洲精品一区二区| 亚洲卡1卡2卡新区网站| 综合久久—本道中文字幕| 久久国产色av免费观看| 欧美国产成人精品一区二区三区 | 国产又色又爽无遮挡免费动态图| 在线亚洲综合欧美网站首页|