Recombinant Human Fc receptor-like protein 1 (FCRL1), partial

中文名稱(chēng)：

人FCRL1重組蛋白
貨號(hào)：

CSB-YP836248HU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

人FCRL1重組蛋白
貨號(hào)：

CSB-EP836248HU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

人FCRL1重組蛋白
貨號(hào)：

CSB-EP836248HU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

人FCRL1重組蛋白
貨號(hào)：

CSB-BP836248HU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

人FCRL1重組蛋白
貨號(hào)：

CSB-MP836248HU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

FCRL1
Uniprot No.：

Q96LA6
別名：

CD307a; Fc receptor homolog 1; Fc receptor like protein 1; Fc receptor-like protein 1; FcR like protein 1; FcR-like protein 1; FCRH 1; FcRH1; FCRL 1; FcRL1; FCRL1_HUMAN; hIFGP 1; hIFGP1; IFGP 1; IFGP family protein 1; IFGP1; Immune receptor translocation associated protein 5; Immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA 5 ; IRTA5 ; RP11 367J7.7
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.
基因功能參考文獻(xiàn)：
1. FCRL1 gene expression down-regulates in both Hashimoto and Graves disease patients compared to normal subjects. PMID: 25738996
2. Data show the Differences in high resolution melting analysis in promoters of tumor markers neuronal membrane glycoprotein M6-B, melanoma antigen family A12 and immunoglobulin superfamily Fc receptor indicated invasiveness of hepatocellular carcinoma. PMID: 23950870
3. Expression level of FCRL1 gene in peripheral blood B-lymphocytes is significantly higher in patients with autoimmune diseases. PMID: 22888639
4. FcRH1 thus has the potential to serve as an activating coreceptor on B cells. PMID: 15479727
5. Down-regulation of FCRL1 is associated with acute lymphoblastic leukemia. PMID: 18802695
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亞細(xì)胞定位：

Cell membrane; Single-pass type I membrane protein.
組織特異性：

Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus mem
數(shù)據(jù)庫(kù)鏈接：

HGNC: 18509

OMIM: 606508

KEGG: hsa:115350

STRING: 9606.ENSP00000357158

UniGene: Hs.656112