在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human F-box/SPRY domain-containing protein 1 (FBXO45)

  • 中文名稱:
    人FBXO45重組蛋白
  • 貨號:
    CSB-YP008510HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人FBXO45重組蛋白
  • 貨號:
    CSB-EP008510HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人FBXO45重組蛋白
  • 貨號:
    CSB-EP008510HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人FBXO45重組蛋白
  • 貨號:
    CSB-BP008510HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人FBXO45重組蛋白
  • 貨號:
    CSB-MP008510HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    FBXO45
  • Uniprot No.:
  • 別名:
    F box protein 45; F-box only protein 45; F-box/SPRY domain-containing protein 1; FBSP1_HUMAN; FBX45; fbxo45; hFbxo45
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    2-286
  • 氨基酸序列
    AAPAPGAGA ASGGAGCSGG GAGAGAGSGS GAAGAGGRLP SRVLELVFSY LELSELRSCA LVCKHWYRCL HGDENSEVWR SLCARSLAEE ALRTDILCNL PSYKAKIRAF QHAFSTNDCS RNVYIKKNGF TLHRNPIAQS TDGARTKIGF SEGRHAWEVW WEGPLGTVAV IGIATKRAPM QCQGYVALLG SDDQSWGWNL VDNNLLHNGE VNGSFPQCNN APKYQIGERI RVILDMEDKT LAFERGYEFL GVAFRGLPKV CLYPAVSAVY GNTEVTLVYL GKPLDG
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons. May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.
  • 基因功能參考文獻:
    1. Relatively low FBXO45 expression in gastric cancer tissues is associated with cancer progression and constitutes an independent prognostic factor PMID: 28011490
    2. Data show that epithelial-mesenchymal transition (EMT)-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 (SPFFbxo45). PMID: 25460509
    3. Fbxo45 is the substrate-receptor subunit of a functional E3 ligase for Par-4 that has a critical role in cancer cell survival. PMID: 24992930
    4. Study found that the R108C mutation in FBXO45 is a rare variant with a modest effect on schizophrenia risk that may disrupt the structure and function of the FBXO45 protein PMID: 24878430
    5. FBXO45 gene consisting of 3 exons, and the vicinity of the transcriptional start site had several estrogen receptor binding consensus sequences. PMID: 16012741
    6. FBXO45 promotes the proteasome-dependent degradation of p73. PMID: 19581926

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, presynaptic cell membrane.
  • 蛋白家族:
    FBXO45/Fsn family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 29148

    OMIM: 609112

    KEGG: hsa:200933

    STRING: 9606.ENSP00000310332

    UniGene: Hs.169815



主站蜘蛛池模板: 性少妇无码播放| 中文无码精品a∨在线| 色综合久久久无码网中文| 中国精学生妹品射精久久| av免费网址在线观看| 欧美精品18videosex性欧美| 欧美亚洲人成网站在线观看 | 香蕉久久久久久久av网站| 在线 亚洲 国产 欧美| 9lporm自拍视频区| 5d肉蒲团之性战奶水| 日本特黄特色特爽大片| 国产成人精品一区二区三区免费看 | 国内精品卡一卡二卡三| 国产尤物人成免费观看| 国产激情高中生呻吟视频| 亚洲a∨国产av综合av下载| 国产精品无码素人福利| 久久午夜色播影院| 精品无码成人片一区二区98| 色翁荡熄又大又硬又粗又视频图片| 丁香五月亚洲综合深深爱| 成人免费网站视频www| 精品无人码麻豆乱码1区2区| 九九热在线视频观看这里只有精品| 亚洲日韩一区二区一无码| 国产精品香蕉视频在线| 国产成人拍精品视频午夜网站| 国产偷抇久久精品a片69 | 狼友网精品视频在线观看| 一本色道久久99一综合| 婷婷无套内射影院| 老司机在线精品视频网站| 欧美国产日韩a在线视频下载 | 国内嫩模私拍精品视频| 欧美人与动人物牲交免费观看久久 | 亚洲精品乱码久久久久久蜜桃 | 国产午夜永久福利视频在线观看| 奇米影视第四色首页| 亚洲美女精品免费视频| 在线播放国产麻豆va剧情|