在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Exosome complex component RRP4 (EXOSC2)

  • 中文名稱:
    人EXOSC2重組蛋白
  • 貨號:
    CSB-YP613428HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人EXOSC2重組蛋白
  • 貨號:
    CSB-EP613428HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人EXOSC2重組蛋白
  • 貨號:
    CSB-EP613428HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人EXOSC2重組蛋白
  • 貨號:
    CSB-BP613428HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人EXOSC2重組蛋白
  • 貨號:
    CSB-MP613428HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    EXOSC2; RRP4Exosome complex component RRP4; Exosome component 2; Ribosomal RNA-processing protein 4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-293
  • 氨基酸序列
    MAMEMRLPVA RKPLSERLGR DTKKHLVVPG DTITTDTGFM RGHGTYMGEE KLIASVAGSV ERVNKLICVK ALKTRYIGEV GDIVVGRITE VQQKRWKVET NSRLDSVLLL SSMNLPGGEL RRRSAEDELA MRGFLQEGDL ISAEVQAVFS DGAVSLHTRS LKYGKLGQGV LVQVSPSLVK RQKTHFHDLP CGASVILGNN GFIWIYPTPE HKEEEAGGFI ANLEPVSLAD REVISRLRNC IISLVTQRMM LYDTSILYCY EASLPHQIKD ILKPEIMEEI VMETRQRLLE QEG
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.
  • 基因功能參考文獻:
    1. The EXOSC2-associated phenotype shows only minimal overlap with the previously reported diseases associated with mutations. PMID: 26843489
    2. Knock-down of hRrp41p or hRrp4p but not PM/Scl-100 or PM/Scl-75 leads to codepletion of other subunits. PMID: 17545563
  • 亞細胞定位:
    Cytoplasm. Nucleus, nucleolus. Nucleus.
  • 蛋白家族:
    RRP4 family
  • 數據庫鏈接:

    HGNC: 17097

    OMIM: 602238

    KEGG: hsa:23404

    STRING: 9606.ENSP00000361433

    UniGene: Hs.654643



主站蜘蛛池模板: 女子spa高潮呻吟抽搐| 韩国美女视频黄是免费| 一本加勒比hezyo无码资源网| 亚洲最大日夜无码中文字幕| 精品国产小视频在线观看| 97人妻无码一区| 亚洲精品一线二线三线区别大吗 | 四川丰满少妇被弄到高潮| 艳妇乳肉豪妇荡乳| 亚洲色大成网站www永久一区| 国产成人av国语在线观看| av国産精品毛片一区二区视频| 无码人妻黑人中文字幕| 无码一区二区三区亚洲人妻| 久久久久欧美精品| 久久天天躁夜夜躁狠狠i女人| 亚洲乱码日产精品bd在线| 国产精品久久自在自线不| 国产成人免费一区二区三区| 一性一交一口添一摸视频| 亚洲人成电影网站色迅雷| 亚洲人成小说网站色在线观看| 欧美群妇大交群| 女被男啪到哭的视频网站| 88久久精品无码一区二区毛片| 十八禁无码精品a∨在线观看| 2023国产精品一卡2卡三卡4卡 | 国产裸体歌舞一区二区| 北条麻妃在线一区二区| 中文字幕一区二区人妻| 天天爽天天摸天天碰| 日韩免费无码成人久久久久久片 | 无码av大香线蕉伊人久久| 少妇与黑人一二三区无码| 国色天香网www在线观看| 亚瑟av亚洲精品一区二区| 国产午夜激无码av毛片不卡| 夜夜爽夜夜叫夜夜高潮漏水 | 少妇粉嫩小泬白浆流出| 免费看男女做爰爽爽视频| 越猛烈欧美xx00动态图|